GOAT ANTI HUMAN TRIM5 alpha (N-TERMINAL)
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Catalog number
MBS223135
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Price
Please ask
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Size
5x0.1 mg
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Products_type
Antibody
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Products_short_name
[TRIM5 ALPHA]
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Other_names
[tripartite motif-containing protein 5 isoform alpha; Tripartite motif-containing protein 5; tripartite motif-containing protein 5; ring finger protein 88; tripartite motif containing 5 transcript variant iota; tripartite motif containing 5 transcript variant kappa; tripartite motif protein TRIM5; tripartite motif containing 5; RING finger protein 88]
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Products_gene_name
[TRIM5 alpha]
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Other_gene_names
[TRIM5; TRIM5; RNF88; TRIM5alpha; RNF88]
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Clonality
Polyclonal
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Specificity
This item specifically recognises an epitope within the N-terminal (NT) region of human TRIM5alpha, otherwise known as RNF88 (RING finger protein 88), a cytoplasmic protein and member of the TRIM/RBCC family, known to play a vital role in species-specific early defence against retrovirus infection. Studies suggest that it is the association of TRIM5 with specific retroviral capsid sequences which determines the effectiveness of the defence against infection. For example, in Old World monkeys, TRIM5alpha specifically associates with HIV type 1 (HIV-1), whereas in humans TRIM5alpha is not effective against HIV-1, but can inhibit strains of the murine leukaemia virus (MLV).
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Form
Purified Purified IgG - liquid
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Concentration
IgG concentration 0.5mg/ml
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Storage_stability
Store at 4 degree C or at -20 degree C if preferred. Storage in frost-free freezers is not recommended. This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use. Shelf Life: 18 months from date of despatch.
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Tested_application
ELISA (EIA), Immunohistology Paraffin*, Western Blot (WB)
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Description
The GOAT ANTI TRIM5 alpha (N-TERMINAL) is a α- or alpha protein sometimes glycoprotein present in blood. This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Antibody against the Hu protein or peptide or recombinant supplied in 1 volumes. Ask for quote if you need bulk.
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Latin name
Capra aegagrus hircus
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Properties
Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
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Gene target
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Gene symbol
TRIM5
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Short name
GOAT ANTI TRIM5 alpha (N-TERMINAL)
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Technique
anti human, anti, Goat, antibody to, anti human antibodies, goats
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Host
Goat, The goat polyclonal antibodies are directed against human genes or rabbit or mouse IgGs (H +L) chain primary antibodies and conjugated for detection. It are very good secondary antibodies that are affinity purified and have a good affinity themselves too. Often KLH is coupled to the antigen so anti KLH can be present in the vial.
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Isotype
IgG
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Species
Human, Goats, Humans
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Alternative name
caprine antibody to H. sapiens TRIM5 a (N-TERMINAL)
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Alternative technique
antibodies, caprine
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Gene info
MeSH Data
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Name
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Concept
Scope note:
Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
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Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
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Qualifiers
ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data
Product images
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