GOAT ANTI HUMAN CD196

• Catalog number
  MBS223815
• Price
  Please ask
• Size
  5x0.1 mg

• Products_type
  Antibody
• Products_short_name
  [CD196]
• Other_names
  [C-C chemokine receptor type 6 isoform A; C-C chemokine receptor type 6; C-C chemokine receptor type 6; chemokine (C-C motif) receptor 6; KY411; CD_antigen: CD196]
• Products_gene_name
  [CD196]
• Other_gene_names
  [Ccr6; Ccr6; CCR-6; KY411; Cmkbr6; CC-CKR-6; Cmkbr6; C-C CKR-6; CC-CKR-6; CCR-6]
• Clonality
  Polyclonal
• Reactivity
  Mouse
• Specificity
  Goat anti Human CD196 antibody recognizes human CD196, otherwise known as CCR6 (C-C chemokine receptor type 6), a transmembrane glycoprotein and member of the G-protein coupled receptor 1 family, which acts as a specific receptor for the C-C chemokine LARC (Liver and activation-regulated chemokine)/MIP-3alpha, a selective chemoattractant which induces calcium flux in CD196-expressing lymphocytes. CD196 is preferentially expressed by B cells, memory T cells and immature dendritic cells and plays an important role in B lineage maturation and antigen-driven B cell differentiation. CD196 acts as a co-receptor for HIV1 infection, and is selectively expressed by mucosa-associated non-Hodgkin's lymphoma, making the interaction between CD196 and LARC a potential therapeutic target in these malignancies. Goat anti Human CD196 antibody cross-reacts with mouse CD196, where linear epitopes are accessible.
• Form
  Purified Purified IgG - liquid
• Concentration
  IgG concentration 1.0mg/ml
• Storage_stability
  Store at 4 degree C or at -20 degree C if preferred. Storage in frost-free freezers is not recommended. This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use. Shelf Life: 18 months from date of despatch.
• Tested_application
  ELISA (EIA), Immunohistology Paraffin, Western Blot (WB)
• Description
  This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Antibody against the Hu protein or peptide or recombinant supplied in 1 volumes. Ask for quote if you need bulk.
• Latin name
  Capra aegagrus hircus
• Properties
  Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.

• Gene target
  CD196  
• Gene symbol
  CCR6
• Short name
  GOAT ANTI CD196
• Technique
  anti human, anti, Goat, antibody to, anti human antibodies, goats
• Host
  Goat, The goat polyclonal antibodies are directed against human genes or rabbit or mouse IgGs (H +L) chain primary antibodies and conjugated for detection. It are very good secondary antibodies that are affinity purified and have a good affinity themselves too. Often KLH is coupled to the antigen so anti KLH can be present in the vial.
• Isotype
  IgG
• Species
  Human, Goats, Humans
• Alternative name
  caprine antibody to H. sapiens CD196
• Alternative technique
  antibodies, caprine

Gene info

• Identity
  HGNC:1607
• Gene
  CCR6
• Long gene name
  C-C motif chemokine receptor 6
• Synonyms gene
  • STRL22
• Synonyms gene name
  • chemokine (C-C motif) receptor 6
• Synonyms
  • CKR-L3
  • GPR-CY4
  • CMKBR6
  • GPR29
  • DRY-6
  • DCR2
  • BN-1
  • CD196
• GenBank acession
  • U68030
• Locus
  6q27
• Discovery year
  1997-04-21
• Entrez gene record
  1235
• Pubmed identfication
  • 8886020
• Classification
  • C-C motif chemokine receptors
  • CD molecules
• VEGA ID
  OTTHUMG00000016015

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

Product images

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