GFRA2, CT (GFRA2, GDNFRB, RETL2, TRNR2, GDNF family receptor alpha-2, GDNF receptor beta, Neurturin receptor alpha, RET ligand 2, TGF-beta-related neurotrophic factor receptor 2)
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Catalog number
MBS6002802
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Price
Please ask
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Size
0,2 mL
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Other size
please contact us to order other different size
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Description
The GFRA2, CT (GFRA2, GDNFRB, RETL2, TRNR2, GDNF family receptor alpha-2, GDNF receptor beta, Neurturin receptor alpha, RET ligand 2, TGF-beta- neurotrophic factor receptor 2) is a α- or alpha protein sometimes glycoprotein present in blood. Aplha, transcription related growth factors and stimulating factors or repressing nuclear factors are complex subunits of proteins involved in cell differentiation. Complex subunit associated factors are involved in hybridoma growth, Eosinohils, eritroid proliferation and derived from promotor binding stimulating subunits on the DNA binding complex. NFKB 105 subunit for example is a polypetide gene enhancer of genes in B cells. FAS ligand and other ligands are binding to the receptor for signaling pathways for example in apoptosis or JNK signaling. Receptor agonists are often tested for drug development. The receptors are ligand binding factors of type 1, 2 or 3 and protein-molecules that receive chemical-signals from outside a cell. When such chemical-signals couple or bind to a receptor, they cause some form of cellular/tissue-response, e.g. a change in the electrical-activity of a cell. In this sense, am olfactory receptor is a protein-molecule that recognizes and responds to endogenous-chemical signals, chemokinesor cytokines e.g. an acetylcholine-receptor recognizes and responds to its endogenous-ligand, acetylcholine. However, sometimes in pharmacology, the term is also used to include other proteins that are drug-targets, such as enzymes, transporters and ion-channels.
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Gene target
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Gene symbol
GFRA2, GDNF, GDNF-AS1, GOLGA5, RET
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Short name
GFRA2, CT (GFRA2, GDNFRB, RETL2, TRNR2, GDNF family receptor alpha-2, GDNF receptor beta, Neurturin receptor alpha, RET ligand 2, TGF-beta- neurotrophic factor receptor 2)
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Alternative name
GFRA2, CT (GFRA2, GDNFRB, RETL2, TRNR2, glial cell derived neurotrophic factor family receptor a-2, glial cell derived neurotrophic factor receptor b, Neurturin receptor a, ret proto-oncogene ligand 2, TGF-b-related neurotrophic factor receptor 2)
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Alternative to gene target
glial cell derived neurotrophic factor, ATF1 and ATF2 and HFB1-GDNF and HSCR3, GDNF and IDBG-17169 and ENSG00000168621 and 2668, protein homodimerization activity, Extracellular, Gdnf and IDBG-128378 and ENSMUSG00000022144 and 14573, BT.58072 and IDBG-630047 and ENSBTAG00000005176 and 386587
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Gene info
Gene info
Gene info
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Identity
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Gene
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Long gene name
GDNF antisense RNA 1
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Synonyms gene name
- GDNF antisense RNA 1 (non-protein coding)
- GDNF antisense RNA 1
- GDNF antisense RNA 1 (head to head)
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year
2011-11-16
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
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VEGA ID
Gene info
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Identity
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Gene
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Long gene name
golgin A5
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Synonyms gene name
- golgi autoantigen, golgin subfamily a, 5
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year
1999-04-28
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Entrez gene record
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Pubmed identfication
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Classification
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VEGA ID
Gene info
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Identity
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Gene
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Long gene name
ret proto-oncogene
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Synonyms gene
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Synonyms gene name
- multiple endocrine neoplasia and medullary thyroid carcinoma 1
- Hirschsprung disease 1
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year
1990-07-15
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Cadherin related
- Receptor tyrosine kinases
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VEGA ID
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Locus Specific Databases
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