Germinal Center Kinase (GC Kinase, GCK, B Lymphocyte Serine/threonine-protein Kinase, BL44, Mitogen-activated Protein Kinase Kinase Kinase Kinase 2, MAP4K2, MAPK/ERK Kinase Kinase Kinase 2, MEK Kinase Kinase 2, MEKKK 2, Rab8-interacting Protein, RAB8IP)

• Catalog number
  MBS616639
• Price
  Please ask
• Size
  5x0.1 mL

• Products_type
  Antibody
• Products_short_name
  [Germinal Center Kinase]
• Products_name_syn
  [Anti -Germinal Center Kinase (GC Kinase, GCK, B Lymphocyte Serine/threonine-protein Kinase, BL44, Mitogen-activated Protein Kinase Kinase Kinase Kinase 2, MAP4K2, MAPK/ERK Kinase Kinase Kinase 2, MEK Kinase Kinase 2, MEKKK 2, Rab8-interacting Protein, RAB8IP)]
• Other_names
  [germinal center kinase]
• Clonality
  Polyclonal
• Reactivity
  Human, Monkey, Mouse, Rat
• Specificity
  Recognizes endogenous levels of total human GCK protein at 91kD. Does not crossreact with HPK or other members of the GCK family. Species Crossreactivity: mouse, rat, monkey.
• Purity
  Affinity Purified Purified by protein A and peptide affinity chromatography.
• Form
  Supplied as a liquid in 10mM sodium HEPES, pH 7.5, 150mM sodium chloride, 0.1mg/ml BSA, 50% glycerol.
• Storage_stability
  May be stored at 4 degree C for short-term only. For long-term storage, store at -20 degree C. Aliquots are stable for at least 12 months at -20 degree C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
• Tested_application
  ELISA (EL/EIA), Western Blot (WB), Immunoprecipitation (IP), Immunocytochemistry (ICC), Immunofluorescence (IF)
• Description
  Serine protease, D- or L-serine arginine rich enzyme of serine threonine kinase with serine that is encoded by the codons UCU, UCC, UCA, UCG, AGU and AGC is an ɑ-amino acid that is used in the biosynthesis of proteins. It contains an α-amino group (which is in the protonated −NH+ 3 form under biological conditions), a carboxyl group. It is non-essential in humans, meaning the body can synthesize it.

• Gene target
  Germinal   Center   Kinase   Kinase   GCK   Lymphocyte   Serine/threonine-protein   Kinase   BL44   Mitogen-activated   Protein   Kinase   Kinase   Kinase   Kinase   MAP4K2   MAPK/ERK   Kinase   Kinase   Kinase   MEK   Kinase   Kinase   MEKKK   Rab8-interacting   Protein   RAB8IP  
• Gene symbol
  MAP4K2, GCK, EPHB2, MAPK1
• Short name
  Germinal Center Kinase (GC Kinase, GCK, B Lymphocyte Serine/threonine-protein Kinase, BL44, Mitogen-activated Protein Kinase Kinase Kinase Kinase 2, MAP4K2, MAPK/ERK Kinase Kinase Kinase 2, MEK Kinase Kinase 2, MEKKK 2, Rab8-interacting Protein, RAB8IP)
• Host
  Rabbit
• Isotype
  IgG
• Alternative name
  Germinal central phosphorylation catalyst (GC phosphorylation catalyst, GCK, B Lymphocyte Serine/threonine-protein phosphorylation catalyst, BL44, Mitogen-activated Protein phosphorylation catalyst phosphorylation catalyst phosphorylation catalyst phosphorylation catalyst 2, mitogen-activated protein kinase kinase kinase kinase 2, MAPK/ERK phosphorylation catalyst phosphorylation catalyst phosphorylation catalyst 2, MEK phosphorylation catalyst phosphorylation catalyst 2, MEKKK 2, Rab8-interacting Protein, RAB8IP)
• Alternative to gene target
  mitogen-activated protein kinase kinase kinase kinase 2, BL44 and GCK and RAB8IP, MAP4K2 and IDBG-55181 and ENSG00000168067 and 5871, transferase activity, Plasma membranes, Map4k2 and IDBG-135906 and ENSMUSG00000024948 and 26412, MAP4K2 and IDBG-643979 and ENSBTAG00000001037 and 520058
• Tissue
  lymphocyte

Gene info

• Identity
  HGNC:6864
• Gene
  MAP4K2
• Long gene name
  mitogen-activated protein kinase kinase kinase kinase 2
• Synonyms gene
  • RAB8IP
• Synonyms
  • GCK
  • BL44
• GenBank acession
  • BC047865
• Locus
  11q13.1
• Discovery year
  1997-08-18
• Entrez gene record
  5871
• Pubmed identfication
  • 7515885
• RefSeq identity
  • NM_004579
• Classification
  • Mitogen-activated protein kinase kinase kinase kinases
• VEGA ID
  OTTHUMG00000045328

Gene info

• Identity
  HGNC:4195
• Gene
  GCK
• Long gene name
  glucokinase
• Synonyms gene
  • MODY2
• Synonyms gene name
  • maturity onset diabetes of the young 2
  • glucokinase (hexokinase 4)
• Synonyms
  • HK4
• Synonyms name
  • hexokinase 4
• GenBank acession
  • AF041014
• Locus
  7p13
• Discovery year
  1991-06-05
• Entrez gene record
  2645
• Pubmed identfication
  • 1740341
  • 1502186
• RefSeq identity
  • NM_000162
• VEGA ID
  OTTHUMG00000022903
• Locus Specific Databases
  • Global Variome shared LOVD
  • LRG_1074

Gene info

• Identity
  HGNC:3393
• Gene
  EPHB2
• Long gene name
  EPH receptor B2
• Synonyms gene
  • DRT
  • ERK
  • EPHT3
• Synonyms gene name
  • EphB2
• Synonyms
  • Hek5
  • Tyro5
• GenBank acession
  • AF025304
• Locus
  1p36.12
• Discovery year
  1995-05-09
• Entrez gene record
  2048
• Pubmed identfication
  • 1648701
• RefSeq identity
  • NM_017449
• Classification
  • EPH receptors
  • MicroRNA protein coding host genes
  • Sterile alpha motif domain containing
• VEGA ID
  OTTHUMG00000002881
• Locus Specific Databases
  • LRG_780

Gene info

• Identity
  HGNC:6871
• Gene
  MAPK1
• Long gene name
  mitogen-activated protein kinase 1
• Synonyms gene
  • PRKM2
  • PRKM1
• Synonyms
  • ERK
  • ERK2
  • p41mapk
  • MAPK2
• GenBank acession
  • M84489
• Locus
  22q11.22
• Discovery year
  1993-11-05
• Entrez gene record
  5594
• Classification
  • Mitogen-activated protein kinases
• VEGA ID
  OTTHUMG00000030508
• Locus Specific Databases
  • LRG_786

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