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Products_type
Antibody
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Products_short_name
[General Transcription Factor IIH, Polypeptide 1, 62kD]
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Products_name_syn
[Anti -General Transcription Factor IIH, Polypeptide 1, 62kD (GTF2H1)]
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Other_names
[general transcription factor IIH subunit 1; general transcription factor IIH subunit 1; general transcription factor IIH, polypeptide 1]
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Other_gene_names
[Gtf2h1; Gtf2h1]
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Clonality
Monoclonal
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Clone
[8C161]
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Reactivity
Human
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Specificity
Recognizes human General Transcription Factor IIH, Polypeptide 1, 62kD.
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Purity
Affinity Purified Purified by Protein G affinity chromatography.
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Form
Supplied as a sterile-filtered liquid in PBS, pH 7.4, 1% BSA, 0.05% sodium azide.
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Storage_stability
May be stored at 4 degree C for short-term only. For long-term storage and to avoid repeated freezing and thawing, add sterile glycerol (40-50%), aliquot and store at -20 degree C. Aliquots are stable for at least 12 months at -20 degree C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
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Tested_application
Western Blot (WB), Immunoprecipitation (IP)
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Description
Aplha, transcription related growth factors and stimulating factors or repressing nuclear factors are complex subunits of proteins involved in cell differentiation. Complex subunit associated factors are involved in hybridoma growth, Eosinohils, eritroid proliferation and derived from promotor binding stimulating subunits on the DNA binding complex. NFKB 105 subunit for example is a polypetide gene enhancer of genes in B cells. The activation of transcription factor subunits is the first step of gene expression, in which a particular segment of DNA is copied into RNA (mRNA) by the enzyme RNA polymerases. Transcription factors, unites and elongations can be RNA and DNA nucleic acids, base pairs of nucleotides . Converting from DNA to RNA is made by enzymatic reactions. During transcription, a DNA sequence is read by an RNA polymerase, which produces a complementary, anti-parallel RNA strand called a primary transcript. Transcriptions are key functions in signal transduction pathways. Signaling ligand binding transcription factors play an important role in transduction cascades.
