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Products_type
Antibody
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Products_short_name
[GABA Receptor A, gamma 2]
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Products_name_syn
[Anti -GABA Receptor A, gamma 2 (GAG2)]
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Other_names
[gamma-aminobutyric acid receptor subunit gamma-2 isoform 2; Gamma-aminobutyric acid receptor subunit gamma-2; gamma-aminobutyric acid receptor subunit gamma-2; OTTHUMP00000160873; OTTHUMP00000160874; OTTHUMP00000224398; OTTHUMP00000224400; GABA(A) receptor subunit gamma-2; gamma-aminobutyric acid (GABA) A receptor, gamma 2; GABA(A) receptor subunit gamma-2]
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Other_gene_names
[GABRG2; GABRG2; CAE2; ECA2; GEFSP3]
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Clonality
Polyclonal
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Reactivity
Bovine, Human, Mouse, Rat
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Specificity
Recognizes GABA receptor A, Gama 2. The 30 AA rat control peptide is 100% conserved in bovine, human and mouse GAG2 (2). It is ~80% conserved in chicken GAB2. Significant homology is also seen with rat GAG1 (64%), ratGAG3 (55%). It is not clear if anti-GAG21 actually reacts with other gamma subunits. No significant homology is observed with other GAA subunits (alpha, beta etc.). Antibody crossreactivity of anti-GAG21 in various species has also not been studied.
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Purity
Serum Serum
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Form
Supplied as a liquid, neat serum, 0.05% sodium azide, 40% glycerol.
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Storage_stability
May be stored at 4 degree C for short-term only. For long-term storage and to avoid repeated freezing and thawing, aliquot and add glycerol (40-50%). Freeze at -20 degree C. Aliquots are stable for at least 12 months at -20 degree C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
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Tested_application
ELISA (EL/EIA), Western Blot (WB)
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Description
The receptors are ligand binding factors of type 1, 2 or 3 and protein-molecules that receive chemical-signals from outside a cell. When such chemical-signals couple or bind to a receptor, they cause some form of cellular/tissue-response, e.g. a change in the electrical-activity of a cell. In this sense, am olfactory receptor is a protein-molecule that recognizes and responds to endogenous-chemical signals, chemokinesor cytokines e.g. an acetylcholine-receptor recognizes and responds to its endogenous-ligand, acetylcholine. However, sometimes in pharmacology, the term is also used to include other proteins that are drug-targets, such as enzymes, transporters and ion-channels.
