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Products_type
Antibody
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Products_short_name
[GABA Receptor A, alpha 1]
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Products_name_syn
[Anti -GABA Receptor A, alpha 1 (Gamma-aminobutyric Acid Receptor Type A alpha 1 Subunit, GABRA)]
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Clonality
Monoclonal
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Clone
[2Q66]
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Reactivity
Bovine, Human
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Specificity
Reacts with the alpha-chain of the GABAA receptor.
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Purity
Purified Purified immunoglobulin.
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Form
Supplied as a liquid in PBS, pH 7.2, 0.1% sodium azide.
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Storage_stability
May be stored at 4 degree C for short-term only. For long-term storage and to avoid repeated freezing and thawing, add glycerol (40-50%) and aliquot. Freeze at -20 degree C. Aliquots are stable for at least 12 months at -20 degree C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
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Tested_application
Western Blot (WB), Immunoprecipitation (IP), Immunohistochemistry (IHC)
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Description
The GABA Receptor A, alpha 1 (Gamma-aminobutyric Acid Receptor A alpha 1 Subunit, GABRA) is a α- or alpha protein sometimes glycoprotein present in blood. The receptors are ligand binding factors of type 1, 2 or 3 and protein-molecules that receive chemical-signals from outside a cell. When such chemical-signals couple or bind to a receptor, they cause some form of cellular/tissue-response, e.g. a change in the electrical-activity of a cell. In this sense, am olfactory receptor is a protein-molecule that recognizes and responds to endogenous-chemical signals, chemokinesor cytokines e.g. an acetylcholine-receptor recognizes and responds to its endogenous-ligand, acetylcholine. However, sometimes in pharmacology, the term is also used to include other proteins that are drug-targets, such as enzymes, transporters and ion-channels.
