FLVCR (Feline Leukemia Virus Subgroup C Receptor-related Protein 1, Feline Leukemia Virus Subgroup C Receptor, hFLVCR, FLVCR1)[FLVCR]

• Catalog number
  MBS648312
• Price
  Please ask
• Size
  NA

• Products_type
  Antibody
• Reactivity
  Human
• Description
  The receptors are ligand binding factors of type 1, 2 or 3 and protein-molecules that receive chemical-signals from outside a cell. When such chemical-signals couple or bind to a receptor, they cause some form of cellular/tissue-response, e.g. a change in the electrical-activity of a cell. In this sense, am olfactory receptor is a protein-molecule that recognizes and responds to endogenous-chemical signals, chemokinesor cytokines e.g. an acetylcholine-receptor recognizes and responds to its endogenous-ligand, acetylcholine. However, sometimes in pharmacology, the term is also used to include other proteins that are drug-targets, such as enzymes, transporters and ion-channels.

• Gene target
  FLVCR   Leukemia   Virus   Subgroup   Receptor-related   Protein   Leukemia   Virus   Subgroup   Receptor   hFLVCR   FLVCR1   [FLVCR]  
• Gene symbol
  FLVCR1, FLVCR1-DT
• Short name
  FLVCR (Feline Leukemia Virus Subgroup C Receptor- Protein 1, Feline Leukemia Virus Subgroup C Receptor, hFLVCR, FLVCR1)[FLVCR]
• Technique
  Feline, felines
• Host
  Rabbit
• Species
  Virus, Sometimes til 5% of an area felines have specific IgGs for the feline retroviral feLV infecting Felidae. Also distemper and leukemia virusses apear in cats and have their specific IgG antibodies that are very stable. All cats used for producing immunoglobulins are screened and tested virus negative. Cat seras have usually higher IgG tirters than dog serum. Feline range = 10 to 20 mg/ml IgGs. Viruses
• Alternative name
  FLVCR (Feline Leukemia Virus Subgroup C Receptor-related Protein 1, Feline Leukemia Virus Subgroup C Receptor, hFLVCR, feline leukemia virus subgroup C cellular receptor 1)[FLVCR]
• Alternative technique
  cats
• Alternative to gene target
  feline leukemia virus subgroup C cellular receptor 1, FLVCR1 and IDBG-106597 and ENSG00000162769 and 28982, heme transporter activity, Plasma membranes, Mfsd7b and IDBG-208638 and ENSMUSG00000066595 and 226844, FLVCR1 and IDBG-638056 and ENSBTAG00000015974 and 533317
• Virus
  leukemia

Gene info

• Identity
  HGNC:24682
• Gene
  FLVCR1
• Long gene name
  FLVCR heme transporter 1
• Synonyms gene
  • AXPC1
• Synonyms gene name
  • ataxia, posterior column 1, with retinitis pigmentosa
  • feline leukemia virus subgroup C cellular receptor 1
• Synonyms
  • FLVCR
  • MFSD7B
  • PCA
  • SLC49A1
• GenBank acession
  • AF118637
• Locus
  1q32.3
• Discovery year
  2007-05-01
• Entrez gene record
  28982
• Pubmed identfication
  • 10400745
  • 10648427
  • 21070897
• RefSeq identity
  • NM_014053
• Classification
  • Solute carriers
• VEGA ID
  OTTHUMG00000036924

Gene info

• Identity
  HGNC:39077
• Gene
  FLVCR1-DT
• Long gene name
  FLVCR1 divergent transcript
• Synonyms gene
  • NCRNA00292
  • FLVCR1-AS1
• Synonyms gene name
  • non-protein coding RNA 292
  • FLVCR1 antisense RNA 1 (non-protein coding)
  • FLVCR1 antisense RNA 1
  • FLVCR1 antisense RNA 1 (head to head)
• Synonyms
  • LQK1
• Locus
  1q32.3
• Discovery year
  2010-10-05
• Entrez gene record
  642946
• Pubmed identfication
  • 11943475
  • 29574975
• RefSeq identity
  • NR_027285
• Classification
  • Divergent transcripts
• VEGA ID
  OTTHUMG00000036923

MeSH Data

• Name
  Leukemia, Experimental
• Concept
  Scope note: Leukemia induced experimentally in animals by exposure to leukemogenic agents, such as VIRUSES; RADIATION; or by TRANSPLANTATION of leukemic tissues.
• Tree numbers
  • C04.557.337.372
  • C04.619.531
  • E05.598.500.496.500
• Qualifiers
  diagnosis, parasitology, immunology, microbiology, diagnostic imaging, physiopathology, rehabilitation, enzymology, etiology, mortality, epidemiology, blood, cerebrospinal fluid, chemically induced, congenital, diet therapy, drug therapy, therapy, psychology, urine, virology, history, classification, economics, embryology, genetics, nursing, radiotherapy, ethnology, prevention & control, pathology, metabolism, complications, surgery

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