Flk-1 Receptor Tyrosine Kinase (KDR, VEGFR2) (Biotin)
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Catalog number
MBS600440
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Price
Please ask
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Size
0.1 mg
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Products_type
Antibody
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Products_short_name
[Flk-1 Receptor Tyrosine Kinase]
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Products_name_syn
[Anti -Flk-1 Receptor Tyrosine Kinase (KDR, VEGFR2) (Biotin)]
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Clonality
Monoclonal
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Clone
[7C29]
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Reactivity
Human
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Specificity
Recognizes mouse FLK13-Mb. Reacts specifically with human FLK-1/VEGFR-2/KDR. No crossreactivity with VGFR-1/FLT-1 or FLT-4.
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Purity
Purified Purified by immunoaffinity chromatography.
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Form
Supplied as a liquid in 100mM Tris, pH 7.5, 0.2% BSA, 0.05% sodium azide, before the addition of glycerol to 40%. Labeled with Biotin.
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Storage_stability
May be stored at 4 degree C for short-term only. For long-term storage, store at -20 degree C. Aliquots are stable for at least 6 months at -20 degree C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
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Tested_application
ELISA (EL/EIA)
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Properties
Biotin conjugates can be detected by horseradish peroxidase, alkaline phosphatase substrates or anti biotin conjugated antibodies. Avidin and Streptavidin bind to the small biotin and are couple to HRP or AP for ELISA. To break the streptavidin Biotin bond we suggest to use a 6 molar guanidine HCl solution with acidity of pH 1.6.
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Conjugation
Biotinylated
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Description
The receptors are ligand binding factors of type 1, 2 or 3 and protein-molecules that receive chemical-signals from outside a cell. When such chemical-signals couple or bind to a receptor, they cause some form of cellular/tissue-response, e.g. a change in the electrical-activity of a cell. In this sense, am olfactory receptor is a protein-molecule that recognizes and responds to endogenous-chemical signals, chemokinesor cytokines e.g. an acetylcholine-receptor recognizes and responds to its endogenous-ligand, acetylcholine. However, sometimes in pharmacology, the term is also used to include other proteins that are drug-targets, such as enzymes, transporters and ion-channels.
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Gene target
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Gene symbol
KDR
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Short name
Flk-1 Receptor Tyrosine Kinase (KDR, VEGFR2) ( )
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Host
Rat
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Isotype
IgG
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Label
Biotin
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Alternative name
Flk-1 Receptor Tyrosine phosphorylation catalyst (kinase insert domain receptor (a type III receptor tyrosine kinase), VEGFR2) (biotinilated)
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Alternative to gene target
kinase insert domain receptor (a type III receptor tyrosine kinase), CD309 and FLK1 and VEGFR and VEGFR2, KDR and IDBG-19161 and ENSG00000128052 and 3791, transferase activity, nuclei, Kdr and IDBG-172240 and ENSMUSG00000062960 and 16542, KDR and IDBG-642352 and ENSBTAG00000000782 and 407170
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Gene info
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