FLASH, NT (FLICE Associated Huge Protein)

Products_type

Antibody
Products_short_name

[FLASH]
Products_name_syn

[Anti -FLASH, NT (FLICE Associated Huge Protein)]
Other_names

[FLASH; CASP8-associated protein 2; CASP8-associated protein 2; human FLASH; OTTHUMP00000016860; FLASH homolog RIP25; FLICE associated huge; CASP8 associated protein 2; FLICE-associated huge protein; caspase 8 associated protein 2; FLICE-associated huge protein]
Other_gene_names

[CASP8AP2; CASP8AP2; CED-4; FLASH; RIP25; FLJ11208; KIAA1315; FLASH; KIAA1315; RIP25]
Clonality

Polyclonal
Specificity

Reacts with the N-terminus of the FLASH protein.
Purity

Affinity Purified Purified by immunoaffinity chromatography.
Form

Supplied as a liquid in PBS, pH 7.2, 0.02% sodium azide.
Storage_stability

May be stored at 4 degree C for short-term only. For long-term storage and to avoid repeated freezing and thawing, aliquot and add glycerol (40-50%). Store at -20 degree C or colder. Aliquots are stable for at least 12 months at -20 degree C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Tested_application

ELISA (EL/EIA), Western Blot (WB)

Identity

HGNC:1500
Gene

CASP10
Long gene name

caspase 10
Synonyms gene name
- caspase 10, apoptosis-related cysteine protease
- caspase 10, apoptosis-related cysteine peptidase
Synonyms
- MCH4
- FLICE-2
Synonyms name
- FAS-associated death domain protein interleukin-1B-converting enzyme 2
GenBank acession
- U60519
Locus

2q33.1
Discovery year

1997-04-21
Entrez gene record

843
Pubmed identfication
- 8755496
RefSeq identity
- NM_032977
Classification
- Caspases
- Death effector domain containing
- Death inducing signaling complex
VEGA ID

OTTHUMG00000132818
Locus Specific Databases
- CASP10base: Mutation registry for Autoimmune lymphoproliferative syndrome, type II (ALPS2)
- LRG_33

Identity

HGNC:1509
Gene

CASP8
Long gene name

caspase 8
Synonyms gene name
- caspase 8, apoptosis-related cysteine protease
- caspase 8, apoptosis-related cysteine peptidase
Synonyms
- MCH5
- MACH
- FLICE
- Casp-8
GenBank acession
- U60520
Locus

2q33.1
Discovery year

1996-11-11
Entrez gene record

841
Pubmed identfication
- 8681376
- 8681377
RefSeq identity
- NM_001228
Classification
- Caspases
- Death effector domain containing
- Death inducing signaling complex
- Ripoptosome
VEGA ID

OTTHUMG00000132821
Locus Specific Databases
- CASP8base: Mutation registry for Caspase 8 deficiency
- LRG_34

Identity

HGNC:1876
Gene

CFLAR
Long gene name

CASP8 and FADD like apoptosis regulator
Synonyms gene
- CASP8AP1
Synonyms gene name
- CASP8 and FADD-like apoptosis regulator
Synonyms
- CASH
- Casper
- CLARP
- FLAME
- FLIP
- I-FLICE
- MRIT
- c-FLIP
- cFLIP
GenBank acession
- AF005774
Locus

2q33.1
Discovery year

1999-05-07
Entrez gene record

8837
Pubmed identfication
- 9208847
- 9217161
RefSeq identity
- NM_003879
Classification
- Receptor ligands
- Death effector domain containing
- Death inducing signaling complex
- Ripoptosome
VEGA ID

OTTHUMG00000132819