Ferritin, Light Chain (FTL) (Microglia Marker)
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Products_type
Antibody
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Products_short_name
[Ferritin, Light Chain (FTL)]
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Products_name_syn
[Ferritin L chain; Ferritin L subunit; Ferritin light chain; Ferritin light polypeptide; FTL; LFTD; NBIA3]
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Other_names
[ferritin light chain; Ferritin light chain; ferritin light chain; ferritin light chain]
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Products_gene_name
[FTL]
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Other_gene_names
[FTL; FTL; LFTD; NBIA3; Ferritin L subunit]
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Clonality
Monoclonal
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Clone
[FTL/1389]
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Reactivity
Human. Others not known.
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Specificity
Mammalian ferritins consist of 24 subunits made up of 2 types of polypeptide chains, ferritin heavy chain and ferritin light chain. Ferritin heavy chains catalyze the first step in iron storage, the oxidation of Fe (II), whereas ferritin light chains promote the nucleation of ferrihydrite, enabling storage of Fe (III). Light chain ferritin is involved in cataracts by at least two mechanisms, hereditary hyperferritinemia cataract syndrome, in which light chain ferritin is overexpressed, and oxidative stress, an important factor in the development of ageing-related cataracts.
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Form
200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.
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Storage_stability
Antibody with azide - store at 2 to 8 degree C. Antibody without azide - store at -20 to -80 degree C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
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Tested_application
Flow Cytometry (FC/FACS), Immunofluorescence (IF), Immunohistochemistry (IHC) Formalin
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Gene target
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Gene symbol
FTL
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Short name
Ferritin, Light Chain (FTL) (Microglia )
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Technique
light, Component cell markers and DNA bp. markers are genetic markers er genes or DNA sequences with a known location on a chromosome that can be used to identify individuals or species. Protein markers in kDA.
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Host
Mouse
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Isotype
IgG1
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Alternative name
Ferritin, Light epitope (FTL) (Microglia detection labelled)
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Gene info
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Identity
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Gene
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Long gene name
ferritin light chain
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Synonyms gene name
- ferritin, light polypeptide
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year
2001-06-22
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
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VEGA ID
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