Ferritin, Light Chain (FTL) (Microglia Marker)

Products_type

Antibody
Products_short_name

[Ferritin, Light Chain (FTL)]
Products_name_syn

[Ferritin L chain; Ferritin L subunit; Ferritin light chain; Ferritin light polypeptide; FTL; LFTD; NBIA3]
Other_names

[ferritin light chain; Ferritin light chain; ferritin light chain; ferritin light chain]
Products_gene_name

[FTL]
Other_gene_names

[FTL; FTL; LFTD; NBIA3; Ferritin L subunit]
Clonality

Monoclonal
Clone

[FTL/2338R]
Reactivity

Human. Others not known.
Specificity

Mammalian ferritins consist of 24 subunits made up of 2 types of polypeptide chains, ferritin heavy chain and ferritin light chain. Ferritin heavy chains catalyze the first step in iron storage, the oxidation of Fe (II), whereas ferritin light chains promote the nucleation of ferrihydrite, enabling storage of Fe (III). Light chain ferritin is involved in cataracts by at least two mechanisms, hereditary hyperferritinemia cataract syndrome, in which light chain ferritin is overexpressed, and oxidative stress, an important factor in the development of ageing-related cataracts.
Form

200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.
Storage_stability

Antibody with azide - store at 2 to 8 degree C. Antibody without azide - store at -20 to -80 degree C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
Tested_application

Immunohistochemistry (IHC) Formalin

Gene target

Ferritin Light Chain FTL Microglia
Gene symbol

FTL
Short name

Ferritin, Light Chain (FTL) (Microglia )
Technique

light, Component cell markers and DNA bp. markers are genetic markers er genes or DNA sequences with a known location on a chromosome that can be used to identify individuals or species. Protein markers in kDA.
Host

Rabbit
Isotype

IgG
Alternative name

Ferritin, Light epitope (FTL) (Microglia detection labelled)