FADD, phosphorylated (Ser191) (FADD Protein, FAS-associating Death Domain-containing Protein, FAS-associated Death Domain Protein, Mediator of rEceptor Induced Toxicity, Fadd, Mort1)

• Catalog number
  MBS629271
• Price
  Please ask
• Size
  0.2 mL

• Products_type
  Antibody
• Products_short_name
  [FADD]
• Products_name_syn
  [Anti -FADD, phosphorylated (Ser191) (FADD Protein, FAS-associating Death Domain-containing Protein, FAS-associated Death Domain Protein, Mediator of rEceptor Induced Toxicity, Fadd, Mort1)]
• Other_names
  [FADD; Protein FADD; protein FADD; OTTHUMP00000235551; growth-inhibiting gene 3 protein; mediator of receptor induced toxicity; mediator of receptor-induced toxicity; Fas-associating protein with death domain; Fas-associating death domain-containing protein; Fas (TNFRSF6)-associated via death domain; FAS-associated death domain protein; FAS-associating death domain-containing protein; Growth-inhibiting gene 3 protein; Mediator of receptor induced toxicity]
• Other_gene_names
  [FADD; FADD; GIG3; MORT1; MGC8528; MORT1]
• Clonality
  Polyclonal
• Reactivity
  Mouse
• Specificity
  Recognizes mouse mFADD when phosphorylated at Ser191.
• Purity
  Affinity Purified Purified by immunoaffinity chromatography.
• Form
  Supplied as a liquid in PBS, 0.09% sodium azide.
• Storage_stability
  May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
• Tested_application
  ELISA (EL/EIA), Western Blot (WB), Immunohistochemistry (IHC)
• Description
  Induced protein genes, factors or kinases, increase the production of (an enzyme or other protein) at the level of genetic transcription. The receptors are ligand binding factors of type 1, 2 or 3 and protein-molecules that receive chemical-signals from outside a cell. When such chemical-signals couple or bind to a receptor, they cause some form of cellular/tissue-response, e.g. a change in the electrical-activity of a cell. In this sense, am olfactory receptor is a protein-molecule that recognizes and responds to endogenous-chemical signals, chemokinesor cytokines e.g. an acetylcholine-receptor recognizes and responds to its endogenous-ligand, acetylcholine. However, sometimes in pharmacology, the term is also used to include other proteins that are drug-targets, such as enzymes, transporters and ion-channels.

• Gene target
  FADD   phosphorylated   Ser191   FADD   Protein   FAS-associating   Death   Domain   Protein   FAS-associated   Death   Domain   Protein   Mediator   rEceptor   Toxicity   Fadd   Mort1  
• Gene symbol
  FAS-AS1, FASN, FAS, FADD
• Short name
  FADD, phosphorylated (Ser191) (FADD Protein, FAS-associating Death Domain- Protein, FAS-associated Death Domain Protein, Mediator of rEceptor Toxicity, Fadd, Mort1)
• Host
  Rabbit
• Isotype
  IgG
• Alternative name
  Fas (tumor necrosis factor receptor superfamily, member 6) (TNFRSF6)-associated via death domain, phosphorylated (Ser191) (Fas (tumor necrosis factor receptor superfamily, member 6) (TNFRSF6)-associated via death domain Protein, Fas (tumor necrosis factor receptor superfamily, member 6)-associating Death Domain-containing Protein, Fas (tumor necrosis factor receptor superfamily, member 6)-associated Death Domain Protein, Mediator on rEceptor Induced Toxicity, Fas (tumor necrosis factor receptor superfamily, member 6) (TNFRSF6)-associated via death domain, Mort1)
• Alternative to gene target
  Fas (TNFRSF6)-associated via death domain, MORT1, FADD and IDBG-62144 and ENSG00000168040 and 8772, identical protein binding, Plasma membranes, Fadd and IDBG-212910 and ENSMUSG00000031077 and 14082, FADD and IDBG-645056 and ENSBTAG00000018274 and 493720

Gene info

• Identity
  HGNC:37128
• Gene
  FAS-AS1
• Long gene name
  FAS antisense RNA 1
• Synonyms gene
  • FASAS
  • FAS-AS
• Synonyms gene name
  • FAS antisense RNA (non-protein coding)
  • FAS antisense RNA 1 (non-protein coding)
• Synonyms
  • SAF
• Locus
  10q23.31
• Discovery year
  2009-07-16
• Entrez gene record
  100302740
• Pubmed identfication
  • 15829500
  • 24811343
  • 27141526
• RefSeq identity
  • NR_028371
• Classification
  • Antisense RNAs

Gene info

• Identity
  HGNC:3594
• Gene
  FASN
• Long gene name
  fatty acid synthase
• Synonyms
  • FAS
  • SDR27X1
• Synonyms name
  • short chain dehydrogenase/reductase family 27X, member 1
• GenBank acession
  • U26644
• Locus
  17q25.3
• Discovery year
  1994-05-17
• Entrez gene record
  2194
• Pubmed identfication
  • 7835891
  • 7567999
  • 19027726
• RefSeq identity
  • NM_004104
• Classification
  • Short chain dehydrogenase/reductase superfamily
  • 7BS orphan methyltransferases
• VEGA ID
  OTTHUMG00000178527

Gene info

• Identity
  HGNC:11920
• Gene
  FAS
• Long gene name
  Fas cell surface death receptor
• Synonyms gene
  • FAS1
  • APT1
  • TNFRSF6
• Synonyms gene name
  • tumor necrosis factor receptor superfamily, member 6
  • Fas (TNF receptor superfamily, member 6)
• Synonyms
  • CD95
  • APO-1
• Synonyms name
  • TNF receptor superfamily member 6
• GenBank acession
  • M67454
• Locus
  10q23.31
• Discovery year
  1992-06-25
• Entrez gene record
  355
• Pubmed identfication
  • 1385299
  • 1385309
• Classification
  • Tumor necrosis factor receptor superfamily
  • Death inducing signaling complex
  • CD molecules
• VEGA ID
  OTTHUMG00000018701
• Locus Specific Databases
  • Autoimmune Lymphoproliferative Syndrome Database (ALPSbase): Database of mutations causing human ALPS
  • LOVD at NCBI
  • LRG_134

Gene info

• Identity
  HGNC:3573
• Gene
  FADD
• Long gene name
  Fas associated via death domain
• Synonyms gene name
  • Fas (TNFRSF6)-associated via death domain
• Synonyms
  • MORT1
  • GIG3
• Synonyms name
  • Fas-associating protein with death domain
  • Fas-associating death domain-containing protein
  • mediator of receptor-induced toxicity
  • growth-inhibiting gene 3 protein
• GenBank acession
  • U24231
• Locus
  11q13.3
• Discovery year
  1999-05-07
• Entrez gene record
  8772
• Pubmed identfication
  • 7536190
  • 7538907
• RefSeq identity
  • NM_003824
• Classification
  • Death effector domain containing
  • Death inducing signaling complex
  • Ripoptosome
• VEGA ID
  OTTHUMG00000167264
• Locus Specific Databases
  • LRG_228

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