Factor VIII Inhibitor Plasma

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Description

Aplha, transcription related growth factors and stimulating factors or repressing nuclear factors are complex subunits of proteins involved in cell differentiation. Complex subunit associated factors are involved in hybridoma growth, Eosinohils, eritroid proliferation and derived from promotor binding stimulating subunits on the DNA binding complex. NFKB 105 subunit for example is a polypetide gene enhancer of genes in B cells. Tissue, pathway, proteinase, peptidase, protease ,acrosin, lipoprotein, activator, caspase, trypsin, papain, esterase inhibitors are proteins or receptor ligands or receptor antagonists that bind to an enzyme receptor and decreases its activity. Since blocking an enzyme's activity can kill a pathogen or correct a metabolic imbalance, many drugs are enzyme inhibitors. Not all receptor antagonist that bind to enzymes are inhibitors; enzyme activator ligands or agonists bind to enzymes and increase their enzymatic activity, while enzyme substrates bind and are converted to products in the normal catalytic cycle of the enzyme.

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Identity

HGNC:2294
Gene

COX8A
Long gene name

cytochrome c oxidase subunit 8A
Synonyms gene
- COX8
Synonyms gene name
- cytochrome c oxidase subunit VIII
- cytochrome c oxidase subunit VIIIA (ubiquitous)
Synonyms
- COX8-2
- COX8L
- VIII-L
- COX
- VIII
GenBank acession
- J04823
Locus

11q13.1
Discovery year

1989-06-30
Entrez gene record

1351
Pubmed identfication
- 2543673
- 2847943
- 26685157
RefSeq identity
- NM_004074
Classification
- Mitochondrial complex IV: cytochrome c oxidase subunits
VEGA ID

OTTHUMG00000167785

Identity

HGNC:30292
Gene

G3BP1
Long gene name

G3BP stress granule assembly factor 1
Synonyms gene name
- GTPase activating protein (SH3 domain) binding protein 1
Synonyms
- HDH-VIII
- G3BP
Synonyms name
- Ras-GTPase-activating protein SH3-domain-binding protein
- DNA helicase VIII
GenBank acession
- BC006997
Locus

5q33.1
Discovery year

2006-10-25
Entrez gene record

10146
Pubmed identfication
- 8649363
- 9889278
- 25229650
RefSeq identity
- NM_005754
Classification
- RNA binding motif containing
- Endoribonucleases
VEGA ID

OTTHUMG00000130123

Identity

HGNC:23356
Gene

MARCHF8
Long gene name

membrane associated ring-CH-type finger 8
Synonyms gene
- MIR
- MARCH8
Synonyms gene name
- c-mir, cellular modulator of immune recognition
- membrane-associated ring finger (C3HC4) 8
- membrane-associated ring finger (C3HC4) 8, E3 ubiquitin protein ligase
Synonyms
- c-MIR
- CMIR
- MARCH-VIII
- RNF178
GenBank acession
- AL833316
Locus

10q11.21-q11.22
Discovery year

2003-11-12
Entrez gene record

220972
Pubmed identfication
- 12582153
- 14722266
RefSeq identity
- NM_145021
Classification
- Ring finger proteins
- Membrane associated ring-CH-type fingers
VEGA ID

OTTHUMG00000019345