EZCyp Active Human Cytochrome P450 2D6

• Catalog number
  MBS845567
• Price
  Please ask
• Size
  5x50 mg

• Products_type
  Recombinant Protein
• Products_short_name
  [Cytochrome P450 2D6]
• Products_name_syn
  [Cytochrome P450 2D6; Cyt2D6; CYPIID6; P450-DB1; Debrisoquine 4-hydroxylase; Active CYP2D6; human cyp2d; recombinant CYP2D6; CYP2D6; CPD6; CYP2D; CYP2DL1; P450C2D; MGC120389; MGC120390; LKM1; liver/kidney microsomal antigen 1]
• Other_names
  [cytochrome P450 2D6 isoform 1; Cytochrome P450 2D6; cytochrome P450 2D6; cytochrome P450 family 2 subfamily D member 6; CYPIID6; Cholesterol 25-hydroxylase]
• Products_gene_name
  [CYP2D6]
• Other_gene_names
  [CYP2D6; CYP2D6; CPD6; CYP2D; CYP2DL1; CYPIID6; P450C2D; P450DB1; CYP2D7AP; CYP2D7BP; CYP2D7P2; CYP2D8P2; P450-DB1; CYP2DL1]
• Form
  Dry powder
• Storage_stability
  Stable for 1 year as supplied. Store dry powder at -20°C. Reconstitute in 100 mM Potassium Phosphate buffer; pH 7.7. Not recommended to be stored in solution. If storing as a solution, aliquot and store at -80°C. Avoid repeated freeze/thaw cycles and use aliquots within one month (the human CYP2D6 will lose approximately 10% activity per week when stored at -80°C). Thaw aliquots rapidly at 37°C and place on ice until use (thawed aliquots should be used within 4 hours).
• Properties
  Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.

• Gene target
  EZCyp   Active   Cytochrome   P450   2D6  
• Gene symbol
  CYP3A7, CYP24A1, CYP1A1, CYP51A1, CYP2D6
• Short name
  EZCyp Active Cytochrome P450 2D6
• Host
  Pichia pastoris co-expressing NADPH-Reuctase
• Species
  Human, Humans
• Alternative name
  EZCyp functionnal H. sapiens Cytochrome P450 2D6

Gene info

• Identity
  HGNC:2640
• Gene
  CYP3A7
• Long gene name
  cytochrome P450 family 3 subfamily A member 7
• Synonyms gene name
  • cytochrome P450, subfamily IIIA, polypeptide 7
  • cytochrome P450, family 3, subfamily A, polypeptide 7
• Synonyms
  • CP37
  • P450-HFLA
• GenBank acession
  • AF315325
• Locus
  7q22.1
• Discovery year
  1992-09-14
• Entrez gene record
  1551
• Pubmed identfication
  • 2722762
• Classification
  • Cytochrome P450 family 3
• VEGA ID
  OTTHUMG00000156726
• Locus Specific Databases
  • PharmVar Human Cytochrome P450 (CYP) Allele Nomenclature

Gene info

• Identity
  HGNC:2602
• Gene
  CYP24A1
• Long gene name
  cytochrome P450 family 24 subfamily A member 1
• Synonyms gene
  • CYP24
• Synonyms gene name
  • cytochrome P450, subfamily XXIV (vitamin D 24-hydroxylase)
  • cytochrome P450, family 24, subfamily A, polypeptide 1
• Synonyms
  • CP24
  • P450-CC24
• GenBank acession
  • U60669
• Locus
  20q13.2
• Discovery year
  1992-09-09
• Entrez gene record
  1591
• Classification
  • Cytochrome P450 family 24
• VEGA ID
  OTTHUMG00000032773

Gene info

• Identity
  HGNC:2595
• Gene
  CYP1A1
• Long gene name
  cytochrome P450 family 1 subfamily A member 1
• Synonyms gene
  • CYP1
• Synonyms gene name
  • cytochrome P450, subfamily I (aromatic compound-inducible), polypeptide 1
  • cytochrome P450, family 1, subfamily A, polypeptide 1
• Synonyms
  • P450DX
  • P1-450
  • P450-C
  • CP11
• GenBank acession
  • BC023019
• Locus
  15q24.1
• Discovery year
  1986-01-01
• Entrez gene record
  1543
• Pubmed identfication
  • 15128046
• RefSeq identity
  • NM_000499
• Classification
  • Cytochrome P450 family 1
• VEGA ID
  OTTHUMG00000142812
• Locus Specific Databases
  • PharmVar Human Cytochrome P450 (CYP) Allele Nomenclature
  • LRG_1262

Gene info

• Identity
  HGNC:2649
• Gene
  CYP51A1
• Long gene name
  cytochrome P450 family 51 subfamily A member 1
• Synonyms gene
  • CYP51
• Synonyms gene name
  • cytochrome P450, 51 (lanosterol 14-alpha-demethylase)
  • cytochrome P450, family 51, subfamily A, polypeptide 1
• Synonyms
  • CP51
  • CYPL1
  • P450L1
  • LDM
  • P450-14DM
• GenBank acession
  • U51685
• Locus
  7q21.2
• Discovery year
  1996-10-26
• Entrez gene record
  1595
• Pubmed identfication
  • 8975714
• Classification
  • Cytochrome P450 family 51
• VEGA ID
  OTTHUMG00000131131

Gene info

• Identity
  HGNC:2625
• Gene
  CYP2D6
• Long gene name
  cytochrome P450 family 2 subfamily D member 6
• Synonyms gene
  • CYP2DL1
  • CYP2D7P2
  • CYP2D7BP
  • CYP2D8P2
  • CYP2D7AP
• Synonyms gene name
  • cytochrome P450, subfamily IID (debrisoquine, sparteine, etc., -metabolizing), polypeptide 6
  • cytochrome P450, family 2, subfamily D, polypeptide 7 pseudogene 2
  • cytochrome P450, subfamily II (debrisoquine, sparteine, etc., -metabolising), polypeptide 7 pseudogene 2
  • cytochrome P450, family 2, subfamily D, polypeptide 8 pseudogene 2
  • cytochrome P450, subfamily IID (debrisoquine, sparteine, etc., -metabolising), polypeptide 8 pseudogene 2
  • cytochrome P450, family 2, subfamily D, polypeptide 6
• Synonyms
  • CPD6
  • P450-DB1
  • CYP2D
  • P450C2D
• GenBank acession
  • M20403
• Locus
  22q13.2
• Discovery year
  1992-04-07
• Entrez gene record
  1565
• Pubmed identfication
  • 8449513
• Classification
  • Cytochrome P450 family 2
• VEGA ID
  OTTHUMG00000150918
• Locus Specific Databases
  • PharmVar Human Cytochrome P450 (CYP) Allele Nomenclature
  • ALSOD, the Amyotrophic Lateral Sclerosis Online Genetic Database
  • LRG_303

MeSH Data

• Name
  Electrophoresis, Gel, Two-Dimensional
• Concept
  Scope note: Electrophoresis in which a second perpendicular electrophoretic transport is performed on the separate components resulting from the first electrophoresis. This technique is usually performed on polyacrylamide gels.
• Tree numbers
  • E05.196.401.250
  • E05.301.300.230
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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