ERCC8, ID (ERCC8, CKN1, CSA, DNA excision repair protein ERCC-8, Cockayne syndrome WD repeat protein CSA)

• Catalog number
  MBS643191
• Price
  Please ask
• Size
  5x0.2 mL

• Products_type
  Antibody
• Products_short_name
  [ERCC8]
• Products_name_syn
  [Anti -ERCC8, ID (ERCC8, CKN1, CSA, DNA excision repair protein ERCC-8, Cockayne syndrome WD repeat protein CSA)]
• Other_names
  [Ercc8 protein; DNA excision repair protein ERCC-8; excision repair cross-complementing rodent repair deficiency, complementation group 8]
• Other_gene_names
  [ercc8; zgc:103550]
• Clonality
  Polyclonal
• Reactivity
  Human, Mouse
• Specificity
  Human, mouse
• Purity
  Affinity Purified Purified by Protein A affinity chromatography.
• Form
  Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.
• Storage_stability
  May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
• Tested_application
  ELISA (EL/EIA), Western Blot (WB), Immunohistochemistry (IHC)

• Gene target
  ERCC8   ERCC8   CKN1   CSA   DNA   excision   repair   protein   ERCC-8   Cockayne   syndrome   repeat   protein   CSA  
• Gene symbol
  ERCC8, ERCC8-AS1, RPL10A, CSH1, SNORD114-8, RNU6-8, PRKDC, SNORD113-8, SNORD116-8, IGKV2OR2-8
• Short name
  ERCC8, ID (ERCC8, CKN1, CSA, DNA excision repair protein ERCC-8, Cockayne syndrome WD repeat protein CSA)
• Technique
  dna
• Host
  Rabbit
• Isotype
  IgG
• Alternative name
  excision repair cross-complementing rodent repair deficiency, complementation family 8, ID (excision repair cross-complementing rodent repair deficiency, complementation family 8, CKN1, CSA, Desoxyribonucleic acid excision repair protein ERCC-8, Cockayne syndrome WD repeat protein CSA)
• Alternative to gene target
  excision repair cross-complementing rodent repair deficiency, complementation group 8, CKN1 and CSA and UVSS2, ERCC8 and IDBG-22959 and ENSG00000049167 and 1161, protein complex binding, nuclei, Ercc8 and IDBG-181454 and ENSMUSG00000021694 and 71991, ERCC8 and IDBG-628902 and ENSBTAG00000021606 and 518857
• Disease
  syndrome

Gene info

• Identity
  HGNC:3439
• Gene
  ERCC8
• Long gene name
  ERCC excision repair 8, CSA ubiquitin ligase complex subunit
• Synonyms gene
  • CKN1
• Synonyms gene name
  • Cockayne syndrome 1 (classical)
  • excision repair cross-complementing rodent repair deficiency, complementation group 8
  • excision repair cross-complementation group 8
• Synonyms
  • CSA
• GenBank acession
  • U28413
• Locus
  5q12.1
• Discovery year
  1995-02-07
• Entrez gene record
  1161
• Pubmed identfication
  • 8596535
• RefSeq identity
  • NM_000082
• Classification
  • WD repeat domain containing
  • ERCC excision repair associated
• VEGA ID
  OTTHUMG00000097741
• Locus Specific Databases
  • LRG_466

Gene info

• Identity
  HGNC:40220
• Gene
  ERCC8-AS1
• Long gene name
  ERCC8 antisense RNA 1
• Locus
  5q12.1
• Discovery year
  2019-07-25
• Entrez gene record
  105378991
• Classification
  • Antisense RNAs

Gene info

• Identity
  HGNC:10299
• Gene
  RPL10A
• Long gene name
  ribosomal protein L10a
• Synonyms gene
  • NEDD6
• Synonyms
  • Csa-19
  • L10A
• GenBank acession
  • U12404
• Locus
  6p21.31
• Discovery year
  1994-01-21
• Entrez gene record
  4736
• Pubmed identfication
  • 7609734
  • 9647638
• RefSeq identity
  • NM_007104
• Classification
  • L ribosomal proteins
  • MicroRNA protein coding host genes
• VEGA ID
  OTTHUMG00000014566

Gene info

• Identity
  HGNC:2440
• Gene
  CSH1
• Long gene name
  chorionic somatomammotropin hormone 1
• Synonyms
  • hCS-A
  • CSA
  • PL
  • CSMT
  • FLJ75407
• Synonyms name
  • chorionic somatomammotropin A
  • placental lactogen
  • choriomammotropin
• GenBank acession
  • J00118
• Locus
  17q23.3
• Discovery year
  1986-01-01
• Entrez gene record
  1442
• Pubmed identfication
  • 6208192
• RefSeq identity
  • NM_001317
• Classification
  • Growth hormone family
• VEGA ID
  OTTHUMG00000171947

Gene info

• Identity
  HGNC:32996
• Gene
  SNORD114-8
• Long gene name
  small nucleolar RNA, C/D box 114-8
• Synonyms
  • 14q(II-8)
• Locus
  14q32.31
• Discovery year
  2006-09-26
• Entrez gene record
  767584
• Pubmed identfication
  • 12045206
• RefSeq identity
  • NR_003200.1
• Classification
  • Small nucleolar RNAs, C/D box

Gene info

• Identity
  HGNC:34285
• Gene
  RNU6-8
• Long gene name
  RNA, U6 small nuclear 8
• Synonyms
  • U6-8
• Locus
  14q12
• Discovery year
  2008-06-10
• Entrez gene record
  101954278
• Pubmed identfication
  • 12711679
• RefSeq identity
  • NR_104088
• Classification
  • Small nuclear RNAs

Gene info

• Identity
  HGNC:9413
• Gene
  PRKDC
• Long gene name
  protein kinase, DNA-activated, catalytic subunit
• Synonyms gene
  • HYRC
  • HYRC1
• Synonyms gene name
  • protein kinase, DNA-activated, catalytic polypeptide
• Synonyms
  • DNPK1
  • p350
  • DNAPK
  • XRCC7
  • DNA-PKcs
  • DNAPKc
  • DNA-PKC
  • p460
• Synonyms name
  • DNA-dependent protein kinase catalytic subunit
• Locus
  8q11.21
• Discovery year
  1993-11-09
• Entrez gene record
  5591
• Pubmed identfication
  • 7638222
• RefSeq identity
  • NM_001081640
• Classification
  • Armadillo like helical domain containing
• VEGA ID
  OTTHUMG00000164239
• Locus Specific Databases
  • LRG_162

Gene info

• Identity
  HGNC:32987
• Gene
  SNORD113-8
• Long gene name
  small nucleolar RNA, C/D box 113-8
• Synonyms
  • 14q(I-8)
• Locus
  14q32.31
• Discovery year
  2006-09-20
• Entrez gene record
  767568
• Pubmed identfication
  • 12045206
• RefSeq identity
  • NR_003236.1
• Classification
  • Small nucleolar RNAs, C/D box

Gene info

• Identity
  HGNC:33074
• Gene
  SNORD116-8
• Long gene name
  small nucleolar RNA, C/D box 116-8
• Synonyms
  • HBII-85-8
• GenBank acession
  • AF250841
• Locus
  15q11.2
• Discovery year
  2007-02-15
• Entrez gene record
  100033420
• Pubmed identfication
  • 11106375
  • 11726556
• RefSeq identity
  • NR_003323
• Classification
  • Small nucleolar RNAs, C/D box

Gene info

• Identity
  HGNC:5811
• Gene
  IGKV2OR2-8
• Long gene name
  immunoglobulin kappa variable 2/OR2-8 (pseudogene)
• Synonyms gene name
  • immunoglobulin kappa variable 2/OR2-8
  • immunoglobulin kappa variable 2/OR2-8 pseudogene
• Synonyms
  • IGKV2/OR2-8
• GenBank acession
  • X51880
• Locus
  2q11.2
• Discovery year
  2000-04-18
• Entrez gene record
  100996600
• RefSeq identity
  • NG_011662
• Classification
  • Immunoglobulin kappa (IGK) orphons

MeSH Data

• Name
  Targeted Gene Repair
• Concept
  Scope note: A technique which uses synthetic oligonucleotides to direct the cell's inherent DNA repair system to correct a mutation at a specific site in an episome or chromosome.
• Tree numbers
  • E02.095.301.500
  • E05.393.420.301.500
  • E05.393.420.601.575.500
• Qualifiers
  legislation & jurisprudence, ethics, mortality, psychology, trends, veterinary, history, classification, economics, instrumentation, methods, nursing, standards, adverse effects, statistics & numerical data

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