ERCC6 (Excision Repair Cross Complement Group 6, CSB)

Products_type

Antibody
Products_short_name

[ERCC6]
Products_name_syn

[Anti -ERCC6 (Excision Repair Cross Complement Group 6, CSB)]
Other_names

[excision repair protein; DNA excision repair protein ERCC-6; DNA excision repair protein ERCC-6; ATP-dependent helicase ERCC6; cockayne syndrome protein CSB; Cockayne syndrome group B protein; excision repair cross-complementing rodent repair deficiency, complementation group 6; ATP-dependent helicase ERCC6; Cockayne syndrome protein CSB]
Other_gene_names

[ERCC6; ERCC6; CSB; CKN2; COFS; ARMD5; COFS1; RAD26; UVSS1; CSB]
Clonality

Monoclonal
Clone

[2A6]
Reactivity

Human
Specificity

Recognizes the ERCC6/CSB protein
Purity

Affinity Purified Purified by Protein G affinity chromatography.
Form

Supplied as a liquid in 0.1M Tris-HCl, pH 7.5.
Storage_stability

May be stored at 4 degree C for short-term only. For long-term storage and to avoid repeated freezing and thawing, aliquot and add glycerol (40-50%). Freeze at -20 degree C. Aliquots are stable for at least 12 months at -20 degree C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Tested_application

ELISA (EL/EIA)

Gene target

ERCC6 Excision Repair Cross Complement Group CSB
Gene symbol

ERCC6, MT-CSB1, MT-CSB3, MT-CSB2, CSH2
Short name

ERCC6 (Excision Repair Cross Complement Group 6, CSB)
Host

Mouse
Isotype

IgG1
Alternative name

excision repair cross-complementing rodent repair deficiency, complementation family 6 (Excision Repair Cross Complement family 6, CSB)
Alternative to gene target

excision repair cross-complementing rodent repair deficiency, complementation group 6, ARMD5 and CKN2 and COFS and COFS1 and CSB and RAD26 and UVSS1, ERCC6 and IDBG-304121 and ENSG00000225830 and 2074, protein N-terminus binding, nuclei, Ercc6 and IDBG-147857 and ENSMUSG00000054051 and 319955, ERCC6 and IDBG-631777 and ENSBTAG00000032527 and 522908

Identity

HGNC:3438
Gene

ERCC6
Long gene name

ERCC excision repair 6, chromatin remodeling factor
Synonyms gene
- CKN2
Synonyms gene name
- excision repair cross-complementing rodent repair deficiency, complementation group 6
- excision repair cross-complementation group 6
Synonyms
- CSB
- RAD26
- ARMD5
Synonyms name
- Cockayne syndrome B protein
GenBank acession
- L04791
Locus

10q11.23
Discovery year

1989-06-30
Entrez gene record

2074
Pubmed identfication
- 1339317
- 19179336
RefSeq identity
- NM_000124
Classification
- ERCC excision repair associated
- B-WICH chromatin-remodelling complex subunits
VEGA ID

OTTHUMG00000018195
Locus Specific Databases
- LRG_465

Name

Targeted Gene Repair
Concept

Scope note: A technique which uses synthetic oligonucleotides to direct the cell's inherent DNA repair system to correct a mutation at a specific site in an episome or chromosome.
Tree numbers
- E02.095.301.500
- E05.393.420.301.500
- E05.393.420.601.575.500
Qualifiers

legislation & jurisprudence, ethics, mortality, psychology, trends, veterinary, history, classification, economics, instrumentation, methods, nursing, standards, adverse effects, statistics & numerical data