ERCC2 (Excision Repair Cross Complement Group 2, EM9, MAG, XPD)

• Catalog number
  MBS600742
• Price
  Please ask
• Size
  0.15 mg

• Products_type
  Antibody
• Products_short_name
  [ERCC2]
• Products_name_syn
  [Anti -ERCC2 (Excision Repair Cross Complement Group 2, EM9, MAG, XPD)]
• Other_names
  [ERCC2; TFIIH basal transcription factor complex helicase XPD subunit; TFIIH basal transcription factor complex helicase XPD subunit; CXPD; BTF2 p80; TFIIH p80; OTTHUMP00000045860; OTTHUMP00000045861; OTTHUMP00000045862; OTTHUMP00000045863; TFIIH 80 kDa subunit; DNA excision repair protein ERCC-2; DNA repair protein complementing XP-D cells; basic transcription factor 2 80 kDa subunit; xeroderma pigmentosum complementary group D; xeroderma pigmentosum group D-complementing protein; TFIIH basal transcription factor complex 80 kDa subunit; TFIIH basal transcription factor complex helicase subunit; excision repair cross-complementing rodent repair deficiency, complementation group 2; Basic transcription factor 2 80 kDa subunit; BTF2 p80; CXPD; DNA excision repair protein ERCC-2; DNA repair protein complementing XP-D cells; TFIIH basal transcription factor complex 80 kDa subunit; TFIIH 80 kDa subunit; TFIIH p80; Xeroderma pigmentosum group D-complementing protein]
• Other_gene_names
  [ERCC2; ERCC2; EM9; TTD; XPD; COFS2; MGC102762; MGC126218; MGC126219; XPD; XPDC]
• Clonality
  Monoclonal
• Clone
  [5i101]
• Specificity
  Recognizes ERCC2 subunit of TFIIH and it has no cross reaction with ERCC3 subunit.
• Purity
  Affinity Purified Purified by Protein G affinity chromatography.
• Form
  Supplied as a liquid in PBS, pH 7.2.
• Storage_stability
  May be stored at 4 degree C for short-term only. For long-term storage and to avoid repeated freezing and thawing, aliquot and add glycerol (40-50%). Freeze at -20 degree C. Aliquots are stable for at least 12 months at -20 degree C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
• Tested_application
  ELISA (EL/EIA)

• Gene target
  ERCC2   Excision   Repair   Cross   Complement   Group   EM9   MAG   XPD  
• Gene symbol
  ERCC2, MAG, RETREG2
• Short name
  ERCC2 (Excision Repair Cross Complement Group 2, EM9, MAG, XPD)
• Host
  Mouse
• Isotype
  IgG2b
• Alternative name
  excision repair cross-complementing rodent repair deficiency, complementation family 2 (Excision Repair Cross Complement family 2, EM9, myelin associated glycoprotein, XPD)
• Alternative to gene target
  myelin associated glycoprotein, GMA and S-MAG and SIGLEC-4A and SIGLEC4A, MAG and IDBG-43939 and ENSG00000105695 and 4099, protein binding, Plasma membranes, Mag and IDBG-171670 and ENSMUSG00000036634 and 17136, BT.96871 and IDBG-635591 and ENSBTAG00000017044 and 540576

Gene info

• Identity
  HGNC:3434
• Gene
  ERCC2
• Long gene name
  ERCC excision repair 2, TFIIH core complex helicase subunit
• Synonyms gene
  • XPD
• Synonyms gene name
  • xeroderma pigmentosum complementary group D
  • excision repair cross-complementing rodent repair deficiency, complementation group 2
  • excision repair cross-complementation group 2
• Synonyms
  • MAG
  • EM9
  • MGC102762
  • MGC126218
  • MGC126219
• Synonyms name
  • excision repair cross-complementing rodent repair deficiency, complementation group 2 protein
  • TFIIH basal transcription factor complex helicase XPB subunit
• Locus
  19q13.32
• Discovery year
  2001-06-22
• Entrez gene record
  2068
• Pubmed identfication
  • 8413672
  • 2184031
• RefSeq identity
  • NM_000400
• Classification
  • Xeroderma pigmentosum complementation groups
  • ERCC excision repair associated
  • DNA helicases
  • General transcription factor IIH complex subunits
• VEGA ID
  OTTHUMG00000048190
• Locus Specific Databases
  • The Globin Gene Server
  • LRG_461

Gene info

• Identity
  HGNC:6783
• Gene
  MAG
• Long gene name
  myelin associated glycoprotein
• Synonyms gene
  • GMA
• Synonyms
  • SIGLEC4A
  • SIGLEC-4A
  • S-MAG
• Synonyms name
  • sialic acid binding Ig-like lectin 4A
• GenBank acession
  • M29273
• Locus
  19q13.1
• Discovery year
  2001-06-22
• Entrez gene record
  4099
• Pubmed identfication
  • 2476987
  • 8432525
• RefSeq identity
  • NM_080600
• Classification
  • C2-set domain containing
  • I-set domain containing
  • Sialic acid binding Ig like lectins
• VEGA ID
  OTTHUMG00000183296

Gene info

• Identity
  HGNC:28450
• Gene
  RETREG2
• Long gene name
  reticulophagy regulator family member 2
• Synonyms gene
  • C2orf17
  • FAM134A
• Synonyms gene name
  • chromosome 2 open reading frame 17
  • family with sequence similarity 134, member A
  • family with sequence similarity 134 member A
• Synonyms
  • MGC3035
  • MAG-2
• GenBank acession
  • AK074983
• Locus
  2q35
• Discovery year
  2004-01-09
• Entrez gene record
  79137
• Pubmed identfication
  • 29097687
• RefSeq identity
  • NM_024293
• VEGA ID
  OTTHUMG00000154577

MeSH Data

• Name
  Targeted Gene Repair
• Concept
  Scope note: A technique which uses synthetic oligonucleotides to direct the cell's inherent DNA repair system to correct a mutation at a specific site in an episome or chromosome.
• Tree numbers
  • E02.095.301.500
  • E05.393.420.301.500
  • E05.393.420.601.575.500
• Qualifiers
  legislation & jurisprudence, ethics, mortality, psychology, trends, veterinary, history, classification, economics, instrumentation, methods, nursing, standards, adverse effects, statistics & numerical data

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