ErbB4 (c-erbB4, HER4)

Products_type

Antibody
Products_short_name

[ErbB4]
Products_name_syn

[Anti -ErbB4 (c-erbB4, HER4)]
Other_names

[erbB4; EGF-like growth factor receptor ErbB4 extracellular domain; receptor tyrosine-protein kinase erbB-4; OTTMUSP00000030425; OTTMUSP00000030426; OTTMUSP00000030427; avian erythroblastosis oncogene B 4; proto-oncogene-like protein c-ErbB-4; v-erb-a erythroblastic leukemia viral oncogene homolog 4 (avian)]
Other_gene_names

[Erbb4; Erbb4; Her4; c-erbB-4]
Clonality

Monoclonal
Clone

[3F167]
Reactivity

Human
Specificity

Recognizes human ErbB4 (c-erbB4, HER4) at 185kD. Inhibits the binding of heregulin (NDF) to c-erbB4. Does not effect tyrosine kinase activity or internalization of c-erbB4.
Purity

Affinity Purified Purified by Protein A affinity chromatography.
Form

Supplied as a liquid in PBS, pH 7.4, 0.2% BSA, 0.09% sodium azide, before the addition of glycerol to 40%. Also available without BSA and azide. See E3451-40BX.
Storage_stability

May be stored at 4 degree C for short-term only. For long-term storage, store at -20 degree C. Aliquots are stable for at least 12 months at -20 degree C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Tested_application

Immunoprecipitation (IP), Flow Cytometry (FC/FACS)

Gene target

ErbB4 c-erbB4 HER4
Gene symbol

ERBB4
Short name

ErbB4 (c-erbB4, HER4)
Host

Mouse
Isotype

IgG2a
Alternative name

v-erb-a erythroblastic leukemia viral oncogene homolog 4 (avian) (c-v-erb-a erythroblastic leukemia viral oncogene homolog 4 (avian), HER4)
Alternative to gene target

v-erb-a erythroblastic leukemia viral oncogene homolog 4 (avian), ALS19 and HER4 and p180erbB4, ERBB4 and IDBG-79992 and ENSG00000178568 and 2066, transferase activity, nuclei, Erbb4 and IDBG-164078 and ENSMUSG00000062209 and 13869, ERBB4 and IDBG-643612 and ENSBTAG00000012647 and

Identity

HGNC:3432
Gene

ERBB4
Long gene name

erb-b2 receptor tyrosine kinase 4
Synonyms gene name
- v-erb-a avian erythroblastic leukemia viral oncogene homolog-like 4
- v-erb-b2 avian erythroblastic leukemia viral oncogene homolog 4
Synonyms
- ALS19
- HER4
Synonyms name
- human epidermal growth factor receptor 4
GenBank acession
- L07868
Locus

2q34
Discovery year

1995-09-07
Entrez gene record

2066
Pubmed identfication
- 7700649
- 17018285
RefSeq identity
- NM_001042599
Classification
- Erb-b2 receptor tyrosine kinases
- MicroRNA protein coding host genes
VEGA ID

OTTHUMG00000133012