ErbB3, phosphorylated (Tyr1222) (c-erbB3, HER3)

Products_type

Antibody
Products_short_name

[ErbB3]
Products_name_syn

[Anti -ErbB3, phosphorylated (Tyr1222) (c-erbB3, HER3)]
Other_names

[ERBB3 protein; ERBB3 protein; receptor tyrosine-protein kinase erbB-3; proto-oncogene-like protein c-ErbB-3; tyrosine kinase-type cell surface receptor HER3; v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian)]
Other_gene_names

[ERBB3; ERBB3; HER3; LCCS2; ErbB-3; c-erbB3; erbB3-S; MDA-BF-1; MGC88033; c-erbB-3; p180-ErbB3; p45-sErbB3; p85-sErbB3]
Clonality

Monoclonal
Clone

[7H10]
Reactivity

Human
Specificity

Recognizes endogenous human ErbB3 only when phosphorylated at tyrosine 1222. Does not crossreact with other tyrosine phosphorylated receptor tyrosine kinases. MW:185kD.
Purity

Supernatant Supernatant
Form

Supplied as a liquid in 10mM sodium HEPES, pH 7.5, 150mM sodium chloride, 0.1mg/ml BSA,
Storage_stability

May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Tested_application

ELISA (EL/EIA), Western Blot (WB)

Gene target

ErbB3 phosphorylated Tyr1222 c-erbB3 HER3
Gene symbol

ERBB3
Short name

ErbB3, phosphorylated (Tyr1222) (c-erbB3, HER3)
Host

Rabbit
Isotype

IgG
Alternative name

v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian), phosphorylated (Tyr1222) (c-v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian), HER3)
Alternative to gene target

v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian), c-erbB-3 and c-erbB3 and ErbB-3 and erbB3-S and HER3 and LCCS2 and MDA-BF-1 and p180-ErbB3 and p45-sErbB3 and p85-sErbB3, ERBB3 and IDBG-39824 and ENSG00000065361 and 2065, transferase activity, Extracellular, Erbb3 and IDBG-197943 and ENSMUSG00000018166 and 13867, ERBB3 and IDBG-636302 and ENSBTAG00000010444 and 785655

Identity

HGNC:3431
Gene

ERBB3
Long gene name

erb-b2 receptor tyrosine kinase 3
Synonyms gene
- LCCS2
Synonyms gene name
- lethal congenital contracture syndrome 2
- v-erb-b2 avian erythroblastic leukemia viral oncogene homolog 3
Synonyms
- HER3
Synonyms name
- human epidermal growth factor receptor 3
GenBank acession
- M34309
Locus

12q13.2
Discovery year

1990-07-15
Entrez gene record

2065
RefSeq identity
- NM_001982
Classification
- Erb-b2 receptor tyrosine kinases
VEGA ID

OTTHUMG00000170140
Locus Specific Databases
- LRG_996