ERBB2, Recombinant, Human (Receptor Tyrosine-protein Kinase erbB-2, Metastatic Lymph Node Gene 19 Protein, MLN 19, Proto-oncogene Neu, Proto-oncogene c-ErbB-2, Tyrosine Kinase-type Cell Surface Receptor HER2, p185erbB2, CD340, HER2, MLN19, NEU, NGL)

  • Catalog number
    MBS635816
  • Price
    Please ask
  • Size
    0.02 mg
  • Products_type
    Recombinant Protein
  • Products_short_name
    [ERBB2]
  • Other_names
    [ERBB2; Receptor tyrosine-protein kinase erbB-2; receptor tyrosine-protein kinase erbB-2; herstatin; p185erbB2; proto-oncogene Neu; c-erb B2/neu protein; proto-oncogene c-ErbB-2; metastatic lymph node gene 19 protein; neuro/glioblastoma derived oncogene homolog; tyrosine kinase-type cell surface receptor HER2; neuroblastoma/glioblastoma derived oncogene homolog; v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog; v-erb-b2 avian erythroblastic leukemia viral oncogene homolog 2; Metastatic lymph node gene 19 protein; MLN 19; Proto-oncogene Neu; Proto-oncogene c-ErbB-2; Tyrosine kinase-type cell surface receptor HER2; p185erbB2]
  • Other_gene_names
    [ERBB2; ERBB2; NEU; NGL; HER2; TKR1; CD340; HER-2; MLN 19; HER-2/neu; HER2; MLN19; NEU; NGL; MLN 19]
  • Purity
    PurifiedPurified (~95%)
  • Form
    Supplied as a lyophillized powder from 0.05mM Acetate buffer, pH 4. Reconstitute with 0.1M Acetate buffer, pH 4.0 at 10ug/ml. Further dilutions can be made in desired buffer.
  • Storage_stability
    Lyophilized powder may be stored at -20 degree C. Stable for 12 months at -20 degree C. Reconstitute with 0.1M Acetate buffer, pH 4.0. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
  • Tested_application
    ELISA (EL/EIA), Western Blot (WB)
  • Description
    For cells, cell lines and tissues in culture till half confluency. cDNA genes are a locus (or region) of DNA for functional transcript RNA or protein. An ELISA is used to detect the expressed protein in biological fluids, serum, saliva. The receptors are ligand binding factors of type 1, 2 or 3 and protein-molecules that receive chemical-signals from outside a cell. When such chemical-signals couple or bind to a receptor, they cause some form of cellular/tissue-response, e.g. a change in the electrical-activity of a cell. In this sense, am olfactory receptor is a protein-molecule that recognizes and responds to endogenous-chemical signals, chemokinesor cytokines e.g. an acetylcholine-receptor recognizes and responds to its endogenous-ligand, acetylcholine. However, sometimes in pharmacology, the term is also used to include other proteins that are drug-targets, such as enzymes, transporters and ion-channels.
  • Properties
    Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
  • Source
    Recombinants or rec. proteins
  • Group
    recombinants
  • Gene target
    ERBB2   Receptor   Tyrosine-protein   Kinase   erbB-2   Metastatic   Lymph   Node   Gene   Protein   MLN   Proto-oncogene   Neu   Proto-oncogene   c-ErbB-2   Tyrosine   Kinase   Surface   Receptor   HER2   p185erbB2   CD340   HER2   MLN19   NEU   NGL  
  • Gene symbol
    ERBB2, MLN, NEU1, NEURL1, LRRC4C, MRLN
  • Short name
    ERBB2, Recombinant, (Receptor Tyrosine-protein Kinase erbB-2, Metastatic Lymph Node 19 Protein, MLN 19, Proto-oncogene Neu, Proto-oncogene c-ErbB-2, Tyrosine Kinase- Surface Receptor HER2, p185erbB2, CD340, HER2, MLN19, NEU, NGL)
  • Technique
    Recombinant, E. coli recombinant proteins are genetic recombinations in Escherichia coli, supplied as white sterile powder lyopillized. MyBioSource advises they will be reconstituted in a buffer soluion or culture medium for cell culture.
  • Species
    Human, Humans
  • Alternative name
    v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian), Rec., H. sapiens (Receptor Tyrosine-protein phosphorylation catalyst erbB-2, Metastatic Lymph Node Gene 19 Protein, MLN 19, Proto-oncogene Neu, Proto-oncogene c-ErbB-2, Tyrosine phosphorylation catalyst-classification cellular Surface Receptor HER2, p185erbB2, CD340, HER2, MLN19, NEU, NGL)
  • Alternative technique
    rec
  • Alternative to gene target
    v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian), CD340 and HER-2 and HER-2/neu and HER2 and MLN 19 and NEU and NGL and TKR1, ERBB2 and IDBG-46068 and ENSG00000141736 and 2064, transferase activity, nuclei, Erbb2 and IDBG-210591 and ENSMUSG00000062312 and 13866, ERBB2 and IDBG-639410 and ENSBTAG00000021798 and 505709
  • Tissue
    cell, lymph, node
Gene info
Gene info
Gene info
  • Identity
    HGNC:7758
  • Gene
    NEU1
  • Long gene name
    neuraminidase 1
  • Synonyms gene
  • Synonyms gene name
    • sialidase 1 (lysosomal sialidase)
    • neuraminidase 1 (lysosomal sialidase)
  • GenBank acession
  • Locus
    6p21.33
  • Discovery year
    2001-06-22
  • Entrez gene record
    4758
  • Pubmed identfication
  • Classification
    • Neuraminidases
  • VEGA ID
    OTTHUMG00000031284
Gene info
  • Identity
    HGNC:7761
  • Gene
    NEURL1
  • Long gene name
    neuralized E3 ubiquitin protein ligase 1
  • Synonyms gene
  • Synonyms gene name
    • neuralized (Drosophila)-like
    • neuralized-like (Drosophila)
    • neuralized homolog (Drosophila)
  • Synonyms
  • GenBank acession
  • Locus
    10q24.33
  • Discovery year
    1999-02-09
  • Entrez gene record
    9148
  • Pubmed identfication
  • Classification
    • Ring finger proteins
  • VEGA ID
    OTTHUMG00000018995
Gene info
Gene info
MeSH Data
  • Name
    Tumor Stem Cell Assay
  • Concept
    Scope note: A cytologic technique for measuring the functional capacity of tumor stem cells by assaying their activity. It is used primarily for the in vitro testing of antineoplastic agents.
  • Tree numbers
    • E01.370.225.500.383.910
    • E01.370.225.500.388.930
    • E05.200.500.383.910
    • E05.200.500.388.930
    • E05.242.383.910
    • E05.242.417.500
    • E05.337.550.200.800
  • Qualifiers
    ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data
Product images
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