Epidermal Growth Factor Receptor, mixed clones (erbB, EGFR) (BSA & Azide Free)
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Catalog number
MBS601844
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Price
Please ask
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Size
0.1 mL
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Products_type
Antibody
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Products_short_name
[Epidermal Growth Factor Receptor, mixed clones]
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Products_name_syn
[Anti -Epidermal Growth Factor Receptor, mixed clones (erbB, EGFR) (BSA & Azide Free)]
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Other_names
[epidermal growth factor receptor; Epidermal growth factor receptor; epidermal growth factor receptor; OTTHUMP00000159661; OTTHUMP00000159662; OTTHUMP00000159663; OTTHUMP00000209210; OTTHUMP00000209211; proto-oncogene c-ErbB-1; cell growth inhibiting protein 40; cell proliferation-inducing protein 61; receptor tyrosine-protein kinase erbB-1; avian erythroblastic leukemia viral (v-erb-b) oncogene homolog; epidermal growth factor receptor; Proto-oncogene c-ErbB-1; Receptor tyrosine-protein kinase erbB-1]
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Other_gene_names
[EGFR; EGFR; ERBB; HER1; mENA; ERBB1; PIG61; ERBB1]
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Clonality
Monoclonal
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Clone
[3F157]
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Reactivity
Human
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Specificity
The cocktail recognizes two separate extracellular domains of EGFR (1st clone blocks the binding of EGF to EGFR while 2nd clone is non-inhibitory). It is specially designed for extremely sensitive detection of EGFR by immunoprecipitation. Species Crossreactivity: human. Does not react with mouse and rat.
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Purity
Affinity Purified Purified by Protein A affinity chromatography.
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Form
Supplied as a liquid in 10mM PBS, pH 7.4. Also available with BSA and azide. See E3375-06E
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Storage_stability
May be stored at 4 degree C for short-term only. For long-term storage and to avoid repeated freezing and thawing, aliquot and add glycerol (40-50%). Freeze at-20 degree C or colder. Aliquots are stable for at least 12 months at-20 degree C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
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Tested_application
Immunoprecipitation (IP)
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Description
Sodium azide NaN3 is often used to prevent antibody degradation in 0,02% W/V concentrations. MyBioSource supplies azide free antibodies on request. Recently MyBioSource made this Epidermal Growth Factor Receptor, mixed clones (erbB, EGFR) (BSA & ) available without azide. It will stick less and is more suitable for ELISA or in vivo studies. However you need to store the @VV@ frozen and ship on dry ice. Aplha, transcription related growth factors and stimulating factors or repressing nuclear factors are complex subunits of proteins involved in cell differentiation. Complex subunit associated factors are involved in hybridoma growth, Eosinohils, eritroid proliferation and derived from promotor binding stimulating subunits on the DNA binding complex. NFKB 105 subunit for example is a polypetide gene enhancer of genes in B cells. The receptors are ligand binding factors of type 1, 2 or 3 and protein-molecules that receive chemical-signals from outside a cell. When such chemical-signals couple or bind to a receptor, they cause some form of cellular/tissue-response, e.g. a change in the electrical-activity of a cell. In this sense, am olfactory receptor is a protein-molecule that recognizes and responds to endogenous-chemical signals, chemokinesor cytokines e.g. an acetylcholine-receptor recognizes and responds to its endogenous-ligand, acetylcholine. However, sometimes in pharmacology, the term is also used to include other proteins that are drug-targets, such as enzymes, transporters and ion-channels.
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Gene target
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Gene symbol
EGFR-AS1, EGILA, EGFR, RHBDF1
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Short name
Epidermal Growth Factor Receptor, mixed clones (erbB, EGFR) (BSA & )
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Host
Mouse
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Isotype
IgG2a
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Alternative name
Epidermal Growth Factor Receptor, mixed clones (erbB, epidermal growth factor receptor) (cow serum albumin & Azide Free)
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Alternative to gene target
epidermal growth factor receptor, ERBB and ERBB1 and HER1 and mENA and PIG61, EGFR and IDBG-16933 and ENSG00000146648 and 1956, transferase activity, nuclei, Egfr and IDBG-151194 and ENSMUSG00000020122 and 13649, EGFR and IDBG-644035 and ENSBTAG00000011628 and 407217
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Gene info
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Identity
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Gene
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Long gene name
EGFR antisense RNA 1
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Locus
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Discovery year
2012-11-06
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
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VEGA ID
Gene info
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Identity
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Gene
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Long gene name
EGFR interacting lncRNA
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Synonyms
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Locus
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Discovery year
2019-09-27
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Pubmed identfication
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Classification
- Long non-coding RNAs with non-systematic symbols
Gene info
Gene info
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Identity
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Gene
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Long gene name
rhomboid 5 homolog 1
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Synonyms gene
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Synonyms gene name
- chromosome 16 open reading frame 8
- rhomboid family 1 (Drosophila)
- rhomboid 5 homolog 1 (Drosophila)
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Synonyms
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GenBank acession
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Locus
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Discovery year
2003-04-07
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
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VEGA ID
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