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Products_type
Antibody
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Products_short_name
[EphB4 Receptor Tyrosine Kinase]
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Products_name_syn
[Anti -EphB4 Receptor Tyrosine Kinase]
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Other_names
[ephrin type-B receptor 4; Ephrin type-B receptor 4; ephrin type-B receptor 4; OTTHUMP00000211367; OTTHUMP00000211368; ephrin receptor EphB4; soluble EPHB4 variant 1; soluble EPHB4 variant 2; soluble EPHB4 variant 3; hepatoma transmembrane kinase; tyrosine-protein kinase TYRO11; tyrosine-protein kinase receptor HTK; EPH receptor B4; Tyrosine-protein kinase TYRO11; Tyrosine-protein kinase receptor HTK]
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Other_gene_names
[EPHB4; EPHB4; HTK; MYK1; TYRO11; HTK; TYRO11]
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Clonality
Monoclonal
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Clone
[6A76]
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Reactivity
Human
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Specificity
Recognizes endogenous human EphB4 receptor at ~110-120kD, with weak crossreactivity with the EphB2 receptor.
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Purity
Affinity Purified Purified by Protein A affinity chromatography.
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Form
Supplied as a liquid in PBS, pH 7.4, 0.1% sodium azide.
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Storage_stability
May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
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Tested_application
ELISA (EL/EIA), Western Blot (WB), Immunoprecipitation (IP), Immunohistochemistry (IHC)
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Description
The receptors are ligand binding factors of type 1, 2 or 3 and protein-molecules that receive chemical-signals from outside a cell. When such chemical-signals couple or bind to a receptor, they cause some form of cellular/tissue-response, e.g. a change in the electrical-activity of a cell. In this sense, am olfactory receptor is a protein-molecule that recognizes and responds to endogenous-chemical signals, chemokinesor cytokines e.g. an acetylcholine-receptor recognizes and responds to its endogenous-ligand, acetylcholine. However, sometimes in pharmacology, the term is also used to include other proteins that are drug-targets, such as enzymes, transporters and ion-channels.
