Eosinophil Major Basic Protein

• Catalog number
  MBS605399
• Price
  Please ask
• Size
  0.1 mg

• Products_type
  Antibody
• Products_short_name
  [Eosinophil Major Basic Protein]
• Products_name_syn
  [Anti -Eosinophil Major Basic Protein]
• Other_names
  [eosinophil major basic protein; Bone marrow proteoglycan; bone marrow proteoglycan; OTTHUMP00000234774; OTTHUMP00000234775; OTTHUMP00000234776; bone-marrow proteoglycan; proteoglycan 2 preproprotein; natural killer cell activator; eosinophil major basic protein; eosinophil granule major basic protein; proteoglycan 2, bone marrow (natural killer cell activator, eosinophil granule major basic protein); Proteoglycan 2Cleaved into the following chain:Eosinophil granule major basic protein; EMBP; MBP; Alternative name(s):; Pregnancy-associated major basic protein]
• Other_gene_names
  [PRG2; PRG2; MBP; BMPG; MBP1; MGC14537; MBP]
• Clonality
  Monoclonal
• Clone
  [1.B.787]
• Reactivity
  Human
• Specificity
  Recognizes human eosinophil major basic protein (14kD) irrespective of the stages of eosinophil activation and can be regarded as a "pan-eosinophil" marker. Recognizes the secreted pro-form of MBP (Pregnancy associated MBP, 23.8kD) and the mature form found in the matrix of the eosinophil large specific granule (13.8kD). Does not crossreact with equine, mouse or rat MBP.
• Purity
  Affinity Purified Purified by Protein A affinity chromatography.
• Form
  Supplied as a liquid in PBS, pH 7.2, 1mg/ml BSA, 10mM sodium azide.
• Storage_stability
  May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
• Tested_application
  ELISA (EL/EIA), Western Blot (WB), Immunohistochemistry (IHC)
• Description
  Basic proteins pH>7 are often produced recombinant and shouldn’t be precipitated by formic acid buffer.

• Gene target
  Eosinophil   Major   Protein  
• Gene symbol
  PRG2, PRG3
• Short name
  Eosinophil Major Protein
• Host
  Mouse
• Isotype
  IgG1
• Alternative name
  Eosinophil Major Basic Protein

Gene info

• Identity
  HGNC:9362
• Gene
  PRG2
• Long gene name
  proteoglycan 2, pro eosinophil major basic protein
• Synonyms gene name
  • proteoglycan 2, bone marrow (natural killer cell activator, eosinophil granule major basic protein)
• Synonyms
  • MBP
  • BMPG
  • proMBP
• Synonyms name
  • eosinophil major basic protein
• GenBank acession
  • BC005929
• Locus
  11q12.1
• Discovery year
  1993-09-29
• Entrez gene record
  5553
• Pubmed identfication
  • 1565101
• RefSeq identity
  • NM_002728
• Classification
  • C-type lectin domain containing
• VEGA ID
  OTTHUMG00000167027

Gene info

• Identity
  HGNC:9363
• Gene
  PRG3
• Long gene name
  proteoglycan 3, pro eosinophil major basic protein 2
• Synonyms gene name
  • proteoglycan 3
• Synonyms
  • MBPH
  • MBP2
• GenBank acession
  • AF132209
• Locus
  11q12.1
• Discovery year
  2000-05-02
• Entrez gene record
  10394
• Pubmed identfication
  • 10318872
  • 11170744
• RefSeq identity
  • NM_006093
• Classification
  • C-type lectin domain containing
• VEGA ID
  OTTHUMG00000167026

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