EGFR

• Catalog number
  MBS438019
• Price
  Please ask
• Size
  5x0.1 mg (With BSA & Azide at 0.2mg/mL)

• Products_type
  Antibody
• Products_short_name
  [EGFR]
• Products_name_syn
  [Erbb1; ERBB1; Errp; HER1; mENA; PIG61; Proto-oncogene c-ErbB-1; Receptor Tyrosine Protein Kinase; ErbB1; Urogastrone; wa2; Wa5]
• Other_names
  [epidermal growth factor receptor isoform a; Epidermal growth factor receptor; epidermal growth factor receptor; proto-oncogene c-ErbB-1; cell growth inhibiting protein 40; cell proliferation-inducing protein 61; receptor tyrosine-protein kinase erbB-1; avian erythroblastic leukemia viral (v-erb-b) oncogene homolog; epidermal growth factor receptor; Proto-oncogene c-ErbB-1; Receptor tyrosine-protein kinase erbB-1]
• Products_gene_name
  [EGFR]
• Other_gene_names
  [EGFR; EGFR; ERBB; HER1; mENA; ERBB1; PIG61; ERBB; ERBB1; HER1]
• Clonality
  Monoclonal
• Clone
  [GFR450]
• Reactivity
  Human.
• Specificity
  This MAb recognizes a protein of 170kDa, identified as EGFR. EGFR is type I receptor tyrosine kinase with sequence homology to erbB-1, -2, -3 -4 or HER-1, -2, -3 -4. It binds to Epidermal Growth Factor (EGF), Transforming Growth Factor-a (TGF-a), Heparin-binding EGF (HB-EGF), amphiregulin, betacellulin and epiregulin. EGFR is overexpressed in tumors of breast, brain, bladder, lung, gastric, head & neck, esophagus, cervix, vulva, ovary, and endometrium. It is predominantly present in squamous cell carcinomas.
• Form
  200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1mg/ml.
• Storage_stability
  Store at 2 to 8 degree C. Antibody is stable for 24 months.
• Tested_application
  Flow Cytometry (FC), Immunofluorescence (IF) Optimal dilution for a specific application should be determined.

• Gene target
  EGFR  
• Gene symbol
  EGFR-AS1, EGILA, EGFR, RHBDF1
• Short name
  EGFR
• Host
  Mouse
• Isotype
  IgG2a, kappa
• Alternative name
  epidermal growth factor receptor
• Alternative to gene target
  epidermal growth factor receptor, ERBB and ERBB1 and HER1 and mENA and PIG61, EGFR and IDBG-16933 and ENSG00000146648 and 1956, transferase activity, nuclei, Egfr and IDBG-151194 and ENSMUSG00000020122 and 13649, EGFR and IDBG-644035 and ENSBTAG00000011628 and 407217

Gene info

• Identity
  HGNC:40207
• Gene
  EGFR-AS1
• Long gene name
  EGFR antisense RNA 1
• Locus
  7p11.2
• Discovery year
  2012-11-06
• Entrez gene record
  100507500
• Pubmed identfication
  • 26271667
  • 28920960
• RefSeq identity
  • NR_047551
• Classification
  • Antisense RNAs
• VEGA ID
  OTTHUMG00000156126

Gene info

• Identity
  HGNC:54482
• Gene
  EGILA
• Long gene name
  EGFR interacting lncRNA
• Synonyms
  • Lnc-EGFR
• Locus
  14q11.2
• Discovery year
  2019-09-27
• Pubmed identfication
  • 28541302
• Classification
  • Long non-coding RNAs with non-systematic symbols

Gene info

• Identity
  HGNC:3236
• Gene
  EGFR
• Long gene name
  epidermal growth factor receptor
• Synonyms gene
  • ERBB
• Synonyms gene name
  • epidermal growth factor receptor (avian erythroblastic leukemia viral (v-erb-b) oncogene homolog)
• Synonyms
  • ERBB1
  • ERRP
• Synonyms name
  • erythroblastic leukemia viral (v-erb-b) oncogene homolog (avian)
  • erb-b2 receptor tyrosine kinase 1
• Locus
  7p11.2
• Discovery year
  1986-01-01
• Entrez gene record
  1956
• Pubmed identfication
  • 1505215
• RefSeq identity
  • NM_005228
• Classification
  • Erb-b2 receptor tyrosine kinases
• VEGA ID
  OTTHUMG00000023661
• Locus Specific Databases
  • LRG_304

Gene info

• Identity
  HGNC:20561
• Gene
  RHBDF1
• Long gene name
  rhomboid 5 homolog 1
• Synonyms gene
  • C16orf8
• Synonyms gene name
  • chromosome 16 open reading frame 8
  • rhomboid family 1 (Drosophila)
  • rhomboid 5 homolog 1 (Drosophila)
• Synonyms
  • EGFR-RS
  • FLJ2235
  • Dist1
  • iRhom1
• GenBank acession
  • BC014425
• Locus
  16p13.3
• Discovery year
  2003-04-07
• Entrez gene record
  64285
• Pubmed identfication
  • 8318735
  • 15965977
• RefSeq identity
  • NM_022450
• Classification
  • Rhomboid family
• VEGA ID
  OTTHUMG00000060719

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