DR6 (Death Receptor 6, BM-018, MGC31965, TNFR Related Death Receptor 6, Tumor Necrosis Factor Receptor Superfamily Member 21, Tumor Necrosis Factor Receptor Superfamily Member 21 Precursor, TNFRSF21)
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Catalog numberMBS605627
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PricePlease ask
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Size5x0.2 mg
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Products_typeAntibody
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Products_short_name[DR6]
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Products_name_syn[Anti -DR6 (Death Receptor 6, BM-018, MGC31965, TNFR Related Death Receptor 6, Tumor Necrosis Factor Receptor Superfamily Member 21, Tumor Necrosis Factor Receptor Superfamily Member 21 Precursor, TNFRSF21)]
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Other_names[DR6; Uncharacterized protein DR6; protein DR6]
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Other_gene_names[DR6; DR6L]
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ClonalityMonoclonal
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Clone[10C17]
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ReactivityHuman
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SpecificityRecognizes human death receptor 6 (DR6) expressed in most human tissues, including heart, placenta, pancreas, thymus, and several non-lymphoid cancer cell lines.
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PurityAffinity Purified Purified by Protein A affinity chromatography.
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FormSupplied as a liquid in PBS, pH 7.4, 0.09% sodium azide.
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Storage_stabilityMay be stored at 4 degree C for short-term only. For long-term storage and to avoid repeated freezing and thawing, add sterile 40-50% glycerol, aliquot and store at -20 degree C. Aliquots are stable for at least 12 months at -20 degree C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
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Tested_applicationImmunoprecipitation (IP), Flow Cytometry (FC/FACS)
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DescriptionAplha, transcription related growth factors and stimulating factors or repressing nuclear factors are complex subunits of proteins involved in cell differentiation. Complex subunit associated factors are involved in hybridoma growth, Eosinohils, eritroid proliferation and derived from promotor binding stimulating subunits on the DNA binding complex. NFKB 105 subunit for example is a polypetide gene enhancer of genes in B cells. Precursor cell, also called a blast cell or simply blast, is a type of partially differentiated, usually unipotent cell that has lost most or all of the stem cell multipotency. The receptors are ligand binding factors of type 1, 2 or 3 and protein-molecules that receive chemical-signals from outside a cell. When such chemical-signals couple or bind to a receptor, they cause some form of cellular/tissue-response, e.g. a change in the electrical-activity of a cell. In this sense, am olfactory receptor is a protein-molecule that recognizes and responds to endogenous-chemical signals, chemokinesor cytokines e.g. an acetylcholine-receptor recognizes and responds to its endogenous-ligand, acetylcholine. However, sometimes in pharmacology, the term is also used to include other proteins that are drug-targets, such as enzymes, transporters and ion-channels.
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Gene target
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Gene symbolTNFRSF21, PHF21A, SPARC, ZNF644, EIF4A2, EXOC1, RSRC1, SPG21, CYRIB, WAC
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Short nameDR6 (Death Receptor 6, BM-018, MGC31965, TNFR Death Receptor 6, Tumor Necrosis Factor Receptor Superfamily Member 21, Tumor Necrosis Factor Receptor Superfamily Member 21 , TNFRSF21)
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HostMouse
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IsotypeIgG1
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Alternative nameDR6 (Death Receptor 6, BM-018, MGC31965, TNFR Related Death Receptor 6, Tumor Necrosis Factor Receptor supergroup Member 21, Tumor Necrosis Factor Receptor supergroup Member 21 Precursor, tumor necrosis factor receptor superfamily, member 21)
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Alternative to gene targettumor necrosis factor receptor superfamily, member 21, TNFRSF21 and IDBG-90063 and ENSG00000146072 and 27242, protein binding, Plasma membranes, Tnfrsf21 and IDBG-184035 and ENSMUSG00000023915 and 94185, TNFRSF21 and IDBG-632394 and ENSBTAG00000020054 and 537922
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Tissuetumor
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Gene info
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Identity
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Gene
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Long gene nameTNF receptor superfamily member 21
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Synonyms gene name
- tumor necrosis factor receptor superfamily, member 21
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year2001-07-27
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Tumor necrosis factor receptor superfamily
- CD molecules
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VEGA ID
Gene info
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Identity
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Gene
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Long gene namePHD finger protein 21A
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Synonyms
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GenBank acession
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Locus
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Discovery year2005-02-07
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- PHD finger proteins
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VEGA ID
Gene info
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Identity
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Gene
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Long gene namesecreted protein acidic and cysteine rich
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Synonyms gene
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Synonyms gene name
- osteonectin
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Synonyms
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Synonyms name
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Locus
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Discovery year2001-06-22
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- SPARC family
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VEGA ID
Gene info
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Identity
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Gene
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Long gene namezinc finger protein 644
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Synonyms
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GenBank acession
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Locus
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Discovery year2004-11-08
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Zinc fingers C2H2-type
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VEGA ID
Gene info
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Identity
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Gene
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Long gene nameeukaryotic translation initiation factor 4A2
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Synonyms gene
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Synonyms gene name
- eukaryotic translation initiation factor 4A, isoform 2
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Synonyms
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GenBank acession
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Locus
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Discovery year1995-05-10
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- DEAD-box helicases
- Small nucleolar RNA protein coding host genes
- MicroRNA protein coding host genes
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VEGA ID
Gene info
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Identity
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Gene
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Long gene nameexocyst complex component 1
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Synonyms gene
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Synonyms gene name
- SEC3-like 1 (S. cerevisiae)
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Synonyms
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GenBank acession
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Locus
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Discovery year2004-01-08
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Exocyst complex
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VEGA ID
Gene info
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Identity
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Gene
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Long gene namearginine and serine rich coiled-coil 1
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Synonyms gene name
- arginine/serine-rich coiled-coil 1
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year2005-02-25
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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VEGA ID
Gene info
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Identity
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Gene
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Long gene nameSPG21 abhydrolase domain containing, maspardin
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Synonyms gene name
- spastic paraplegia 21 (autosomal recessive, Mast syndrome)
- SPG21, maspardin
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Synonyms
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GenBank acession
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Locus
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Discovery year2004-04-30
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Abhydrolase domain containing
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VEGA ID
Gene info
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Identity
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Gene
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Long gene nameCYFIP related Rac1 interactor B
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Synonyms gene
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Synonyms gene name
- family with sequence similarity 49, member B
- family with sequence similarity 49 member B
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Synonyms
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GenBank acession
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Locus
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Discovery year2004-08-20
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- MicroRNA protein coding host genes
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VEGA ID
Gene info
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Identity
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Gene
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Long gene nameWW domain containing adaptor with coiled-coil
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Synonyms gene name
- WW domain-containing adaptor with coiled coil
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Synonyms
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GenBank acession
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Locus
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Discovery year2004-01-22
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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VEGA ID
MeSH Data
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Name
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ConceptScope note: A cytologic technique for measuring the functional capacity of tumor stem cells by assaying their activity. It is used primarily for the in vitro testing of antineoplastic agents.
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Tree numbers
- E01.370.225.500.383.910
- E01.370.225.500.388.930
- E05.200.500.383.910
- E05.200.500.388.930
- E05.242.383.910
- E05.242.417.500
- E05.337.550.200.800
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Qualifiersethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data