DR5, soluble Recombinant, Human (Apo2, Trail-R2, TRAIL Receptor2, Trick2, Killer, Death Receptor5, CD262, KILLER, KILLER/DR5, TNFRSF10B, TRANCE-R, TRICKB, Tumor Necrosis Factor Receptor Superfamily, Member 10b, ZTNFR9)
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Catalog number
MBS636139
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Price
Please ask
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Size
0.05 mg
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Products_type
Active Protein
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Products_short_name
[DR5, soluble Recombinant]
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Other_names
[DR5; Tumor necrosis factor receptor superfamily member 10B; tumor necrosis factor receptor superfamily member 10B; Fas-like protein; death receptor 5; cytotoxic TRAIL receptor-2; apoptosis inducing receptor TRAIL-R2; apoptosis inducing protein TRICK2A/2B; TNF-related apoptosis-inducing ligand receptor 2; death domain containing receptor for TRAIL/Apo-2L; tumor necrosis factor receptor-like protein ZTNFR9; p53-regulated DNA damage-inducible cell death receptor(killer); tumor necrosis factor receptor superfamily, member 10b; Death receptor 5; TNF-related apoptosis-inducing ligand receptor 2]
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Other_gene_names
[TNFRSF10B; TNFRSF10B; DR5; CD262; KILLER; TRICK2; TRICKB; ZTNFR9; TRAILR2; TRICK2A; TRICK2B; TRAIL-R2; KILLER/DR5; DR5; KILLER; TRAILR2; TRICK2; ZTNFR9; TRAIL receptor 2; TRAIL-R2]
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Purity
Highly Purified98% by SDS-PAGE and HPLC analyses. Endotoxin: 0.1ng/ug (1EU/ug)
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Form
Supplied as a lyophilized powder with no additives. Reconsitutie with ddH2O, carrier protein to 0.1-1mg/ml. This solution can then be diluted into other aqueous buffers.
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Storage_stability
Lyophilized powder may be stored at -20 degree C. Reconstitute to nominal volume by adding sterile ddH2O, carrier protein. Aliquot and store at -20 degree C. Reconstituted product is stable for 12 months at -20 degree C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
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Description
Aplha, transcription related growth factors and stimulating factors or repressing nuclear factors are complex subunits of proteins involved in cell differentiation. Complex subunit associated factors are involved in hybridoma growth, Eosinohils, eritroid proliferation and derived from promotor binding stimulating subunits on the DNA binding complex. NFKB 105 subunit for example is a polypetide gene enhancer of genes in B cells. The receptors are ligand binding factors of type 1, 2 or 3 and protein-molecules that receive chemical-signals from outside a cell. When such chemical-signals couple or bind to a receptor, they cause some form of cellular/tissue-response, e.g. a change in the electrical-activity of a cell. In this sense, am olfactory receptor is a protein-molecule that recognizes and responds to endogenous-chemical signals, chemokinesor cytokines e.g. an acetylcholine-receptor recognizes and responds to its endogenous-ligand, acetylcholine. However, sometimes in pharmacology, the term is also used to include other proteins that are drug-targets, such as enzymes, transporters and ion-channels.
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Properties
Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
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Source
Recombinants or rec. proteins
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Group
recombinants
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Gene target
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Gene symbol
TNFRSF10B, PCAT7, CD82, CLDN3, TNFRSF11A, RRAS, DAD1P1, HNRNPR, CLDN4, MC1R
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Short name
DR5, soluble Recombinant, (Apo2, Trail-R2, TRAIL Receptor2, Trick2, Killer, Death Receptor5, CD262, KILLER, KILLER/DR5, TNFRSF10B, TRANCE-R, TRICKB, Tumor Necrosis Factor Receptor Superfamily, Member 10b, ZTNFR9)
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Technique
Recombinant, E. coli recombinant proteins are genetic recombinations in Escherichia coli, supplied as white sterile powder lyopillized. MyBioSource advises they will be reconstituted in a buffer soluion or culture medium for cell culture.
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Host
E Coli
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Species
Human, Humans
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Alternative name
DR5, soluble Rec., H. sapiens (Apo2, Trail-R2, TRAIL Receptor2, Trick2, Killer, Death Receptor5, CD262, KILLER, KILLER/DR5, tumor necrosis factor receptor superfamily, member 10b, TRANCE-R, TRICKB, Tumor Necrosis Factor Receptor supergroup, Member 10b, ZTNFR9)
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Alternative technique
rec
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Alternative to gene target
tumor necrosis factor receptor superfamily, member 10b, CD262 and DR5 and KILLER and KILLER/DR5 and TRAIL-R2 and TRAILR2 and TRICK2 and TRICK2A and TRICK2B and TRICKB and ZTNFR9, TNFRSF10B and IDBG-11376 and ENSG00000120889 and 8795, TRAIL binding, Plasma membranes
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Tissue
tumor
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Gene info
Gene info
Gene info
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Identity
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Gene
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Long gene name
CD82 molecule
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Synonyms gene
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Synonyms gene name
- kangai 1 (suppression of tumorigenicity 6, prostate; CD82 antigen (R2 leukocyte antigen, antigen detected by monoclonal and antibody IA4))
- CD82 antigen
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year
1994-01-10
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Entrez gene record
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RefSeq identity
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Classification
- Tetraspanins
- CD molecules
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VEGA ID
Gene info
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Identity
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Gene
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Long gene name
claudin 3
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Synonyms gene
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year
1998-07-23
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
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VEGA ID
Gene info
Gene info
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Identity
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Gene
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Long gene name
RAS related
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Synonyms gene name
- related RAS viral (r-ras) oncogene homolog
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Synonyms
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Synonyms name
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Locus
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Discovery year
2001-06-22
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
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VEGA ID
Gene info
Gene info
Gene info
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Identity
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Gene
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Long gene name
claudin 4
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Synonyms gene
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year
1998-04-22
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
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VEGA ID
Gene info
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Identity
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Gene
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Long gene name
melanocortin 1 receptor
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Synonyms gene name
- melanocortin 1 receptor (alpha melanocyte stimulating hormone receptor)
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Synonyms
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Synonyms name
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Locus
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Discovery year
1993-07-27
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
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VEGA ID
MeSH Data
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Name
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Concept
Scope note:
The initial culturing of cells derived directly from fresh TISSUES.
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Tree numbers
- E01.370.225.500.223.500
- E05.200.500.265.500
- E05.242.223.500
- E05.481.500.249.500
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Qualifiers
ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data
Product images
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