Desmoplakin 1,2 (Desmoplakin I, DP I, DPI, Desmoplakin II, DP II, DPII, DSP, 250/210kD Paraneoplastic Pemphigus Antigen)

• Catalog number
  MBS605616
• Price
  Please ask
• Size
  0.05 mg

• Products_type
  Antibody
• Products_short_name
  [Desmoplakin 1,2]
• Products_name_syn
  [Anti -Desmoplakin 1,2 (Desmoplakin I, DP I, DPI, Desmoplakin II, DP II, DPII, DSP, 250/210kD Paraneoplastic Pemphigus Antigen)]
• Other_names
  [desmoplakin isoform I; Desmoplakin; desmoplakin; desmoplakin I; desmoplakin II; OTTHUMP00000016001; OTTHUMP00000221297; 250/210 kDa paraneoplastic pemphigus antigen; desmoplakin; 250/210 kDa paraneoplastic pemphigus antigen]
• Other_gene_names
  [DSP; DSP; DP; DPI; DPII]
• Clonality
  Monoclonal
• Clone
  [10B2716]
• Reactivity
  Human
• Specificity
  Recognizes human desmoplakin 1 and 2 from stratified epithelia, simple epithelia including glands, urothelium, thymic reticular epithelium, hepatocytes, intercalated disks of myocardium and arachnoid cells of meninges. Can be used for the detection of primary and metastatic carcinomas. Species Crossreactivity: bovine, chicken, mouse, rat
• Purity
  Affinity Purified Purified by Protein A affinity chromatography.
• Form
  Supplied as a liquid in PBS, pH 7.4, 0.09% sodium azide.
• Storage_stability
  May be stored at 4 degree C for short-term only. For long-term storage and to avoid repeated freezing and thawing, aliquot and store at -20 degree C. Aliquots are stable for at least 12 months at -20 degree C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
• Tested_application
  Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
• Description
  Antigens are peptides or recombinant or native dependent on the production method.

• Gene target
  Desmoplakin   Desmoplakin   DPI   Desmoplakin   DPII   DSP   250/210kD   Paraneoplastic   Pemphigus  
• Gene symbol
  DSP
• Short name
  Desmoplakin 1 2 (Desmoplakin I, DP I, DPI, Desmoplakin II, DP II, DPII, DSP, 250/210kD Paraneoplastic Pemphigus Antigen)
• Technique
  antigen, antigenes
• Host
  Mouse
• Isotype
  IgG1
• Alternative name
  Desmoplakin 1,2 (Desmoplakin I, DP I, DPI, Desmoplakin II, DP II, DPII, desmoplakin, 250/210kD Paraneoplastic Pemphigus protein)
• Alternative technique
  antigenes
• Alternative to gene target
  desmoplakin, DP and DPI and DPII, DSP and IDBG-59899 and ENSG00000096696 and 1832, protein binding, nuclei, Dsp and IDBG-145817 and ENSMUSG00000054889 and 109620, DSP and IDBG-636412 and ENSBTAG00000015106 and 514360

Gene info

• Identity
  HGNC:3052
• Gene
  DSP
• Long gene name
  desmoplakin
• Synonyms gene name
  • desmoplakin (DPI, DPII)
• Synonyms
  • KPPS2
  • PPKS2
  • DPI
  • DPII
• GenBank acession
  • J05211
• Locus
  6p24.3
• Discovery year
  1991-03-04
• Entrez gene record
  1832
• Pubmed identfication
  • 1889810
• RefSeq identity
  • NM_004415
• Classification
  • Plakins
• VEGA ID
  OTTHUMG00000014212
• Locus Specific Databases
  • Global Variome shared LOVD
  • LRG_423

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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