Desmoglein-1 (DSG1)
-
Catalog numberMBS439914
-
PricePlease ask
-
Size0.02 mg (With BSA & Azide at 0.2mg/mL)
-
-
Products_typeAntibody
-
Products_short_name[Desmoglein-1 (DSG1)]
-
Products_name_syn[Cadherin family member 4; CDHF4; Desmoglein-1; Desmosomal glycoprotein 1; DG1; DSG1; EPKHE; EPKHIA; Pemphigus foliaceus antigen; PPKS1; SPPK1]
-
Other_names[desmoglein-1 preproprotein; Desmoglein-1; desmoglein-1; desmoglein 1; Cadherin family member 4; Desmosomal glycoprotein 1; DG1; DGI; Pemphigus foliaceus antigen]
-
Products_gene_name[DSG1]
-
Other_gene_names[DSG1; DSG1; DG1; DSG; CDHF4; EPKHE; PPKS1; SPPK1; EPKHIA; CDHF4; DG1; DGI]
-
ClonalityMonoclonal
-
Clone[DSG1/1733]
-
ReactivityHuman. Others not known.
-
SpecificityRecognizes a protein of ~150kDa, identified as Desmoglein-1 (DSG1). Desmoglein-1 is a member of the desmosomal cadherin family. Desmosomes are intercellular adhering junctions that represent cell surface attachment sites for intermediate filament. Desmocollins and desmogleins are the main desmosomal transmembrane proteins. Desmogleins consist of Dsg1, Dsg2, Dsg3, and Dsg4 isoforms. Within the desmosome, the extracellular domain of desmoglein is essential for calcium dependent heterophilic binding to the desmocollins, whereas the intracellular domain is essential for binding to the desmosomal plaque protein, plakoglobin. Desmoglein 1 is synthesized exclusively in the suprabasal layers. Intact and functionally active desmoglein 1 is essential to epidermal integrity.
-
Form200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.
-
Storage_stabilityAntibody with azide - store at 2 to 8 degree C. Antibody without azide - store at -20 to -80 degree C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
-
Tested_applicationFlow Cytometry (FC/FACS), Immunofluorescence (IF), Immunohistochemistry (IHC) Formalin
-
Gene target
-
Gene symbolDSG1-AS1, DSG1
-
Short nameDesmoglein-1 (DSG1)
-
HostMouse
-
IsotypeIgG1, kappa
-
Alternative nameDesmoglein-1 (desmoglein 1)
-
Alternative to gene targetdesmoglein 1, CDHF4 and DG1 and DSG and EPKHE and EPKHIA and PPKS1 and SPPK1, DSG1 and IDBG-2020 and ENSG00000134760 and 1828, gamma-catenin binding, Cell surfaces, DSG1 and IDBG-643764 and ENSBTAG00000013831 and 281131
-
Gene info
-
Identity
-
Gene
-
Long gene nameDSG1 antisense RNA 1
-
Locus
-
Discovery year2014-07-30
-
Entrez gene record
-
Classification
- Antisense RNAs
-
VEGA ID
Gene info
-
Identity
-
Gene
-
Long gene namedesmoglein 1
-
Synonyms gene
-
Synonyms
-
GenBank acession
-
Locus
-
Discovery year1991-03-04
-
Entrez gene record
-
Pubmed identfication
-
RefSeq identity
-
Classification
- Desmosomal cadherins
-
VEGA ID