Defensin 1 (human) (Human Neutrophil Peptide-1, HNP-1)
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Catalog numberMBS659788
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PricePlease ask
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Size5x1 mg
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Products_typePeptide
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Products_short_name[Defensin 1]
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Other_names[defensin 1; Neutrophil defensin 1; neutrophil defensin 1; defensin, alpha 2; myeloid-related sequence; defensin, alpha 1, myeloid-related sequence; defensin, alpha 1; Defensin, alpha 1; HNP-1; HP-1; HP1Cleaved into the following 2 chains:HP 1-56Neutrophil defensin 2; Alternative name(s):; HNP-2]
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Other_gene_names[DEFA1; DEFA1; HP1; MRS; DEF1; HP-1; DEFA2; HNP-1; DEF1; DEFA2; MRS; HP-1; HP1; HP-2; HP2]
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ReactivityHuman
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PurityHighly Purified~95%. Purified by HPLC.
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FormSupplied as a lyophilized powder.
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Storage_stabilityLyophilized powder may be stored at 4 degree C for short-term only. Stable for 12 months at -20 degree C. Reconstitute to nominal volume (see reconstitution instructions for peptides) and store at -20 degree C. For maximum recovery of product, centrifuge the original vial prior to removing the cap. Further dilutions can be made in assay buffer._x000B_ _x000B_
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Descriptionhuman, mouse or other beta β- and alpha α- defensins are expressed by neutrophils ( α- ), lymphocytes and epithelial cells. DEFA DEFB genes defend the host against pathogens. GENTAUR supplies anti-defensins, monclonals, polyclonals antisera and recombinant DEFs or peptides of defensin. Peptides short amino acid chains or epitopes or blocking antagonists. The shortest peptides are dipeptides, consisting of 2 amino acids joined by a single peptide bond, followed by tripeptides, tetra peptides, ... till polypeptides that are long, continuous, and unbranched synthetic peptide chains. These biological oligomers and polymers can be Solid-phase peptide synthesis (SPPS), or in continue produced for custom peptide synthesis projects. The High-efficiency solid phase peptide synthesis (HE-SPPS) is give very low production costs.
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PropertiesHuman proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
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Gene target
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Gene symbolDEFA1, DEFA3, KLK8, IGHVII-1-1, MIR1-1, TRUND-NNN8-1, TRUND-NNN7-1, IGKV1OR2-1, MIR1289-1, MIR101-1
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Short nameDefensin 1 ( ) ( Neutrophil Peptide-1, HNP-1)
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Techniquepeptide, peptides
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HostSynthetic peptide
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SpeciesHuman, Humans
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Alternative nameDefensin 1 (H. sapiens) (H. sapiens Neutrophil short protein sequence-1, HNP-1)
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Alternative techniquepeptides
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Gene info
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Identity
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Gene
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Long gene namedefensin alpha 1
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Synonyms gene
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Synonyms gene name
- defensin, alpha 2
- defensin, alpha 1, myeloid-related sequence
- defensin, alpha 1
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Synonyms
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GenBank acession
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Locus
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Discovery year1988-06-27
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Defensins, alpha
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VEGA ID
Gene info
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Identity
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Gene
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Long gene namedefensin alpha 3
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Synonyms gene
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Synonyms gene name
- defensin, alpha 3, neutrophil-specific
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Synonyms
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GenBank acession
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Locus
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Discovery year1993-11-05
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Defensins, alpha
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VEGA ID
Gene info
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Identity
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Gene
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Long gene namekallikrein related peptidase 8
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Synonyms gene
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Synonyms gene name
- kallikrein 8 (neuropsin/ovasin)
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Synonyms
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GenBank acession
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Locus
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Discovery year1999-09-09
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Kallikreins
- Serine proteases
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VEGA ID
Gene info
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Identity
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Gene
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Long gene nameimmunoglobulin heavy variable (II)-1-1 (pseudogene)
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Synonyms gene name
- immunoglobulin heavy variable (II)-1-1
- immunoglobulin heavy variable (II)-1-1 pseudogene
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Synonyms
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GenBank acession
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Locus
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Discovery year2000-04-17
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Entrez gene record
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RefSeq identity
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Classification
- Immunoglobulin heavy locus at 14q32.33
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VEGA ID
Gene info
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Identity
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Gene
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Long gene namemicroRNA 1-1
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Synonyms gene
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Synonyms
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Locus
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Discovery year2004-04-23
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Entrez gene record
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RefSeq identity
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Classification
- MicroRNA MIR1/206 family
Gene info
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Identity
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Gene
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Long gene nametRNA-undetermined (NNN) 8-1
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Synonyms gene name
- transfer RNA-undetermined (NNN) 8-1
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GenBank acession
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Locus
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Discovery year2014-06-20
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Entrez gene record
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Pubmed identfication
Gene info
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Identity
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Gene
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Long gene nametRNA-undetermined (NNN) 7-1
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Synonyms gene name
- transfer RNA-undetermined (NNN) 7-1
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GenBank acession
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Locus
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Discovery year2014-06-20
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Entrez gene record
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Pubmed identfication
Gene info
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Identity
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Gene
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Long gene nameimmunoglobulin kappa variable 1/OR2-1 (pseudogene)
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Synonyms gene
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Synonyms gene name
- immunoglobulin kappa variable 1/OR-1
- immunoglobulin kappa variable 1/OR-1 pseudogene
- immunoglobulin kappa variable 1/OR-1 (pseudogene)
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Synonyms
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GenBank acession
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Locus
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Discovery year2000-04-18
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Entrez gene record
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Pubmed identfication
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Classification
- Immunoglobulin kappa (IGK) orphons
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VEGA ID
Gene info
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Identity
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Gene
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Long gene namemicroRNA 1289-1
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Synonyms gene
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Synonyms
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Locus
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Discovery year2008-11-03
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Entrez gene record
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RefSeq identity
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Classification
- MicroRNA MIR1289 family
Gene info
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Identity
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Gene
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Long gene namemicroRNA 101-1
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Synonyms gene
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Synonyms
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Locus
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Discovery year2004-04-23
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Entrez gene record
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RefSeq identity
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Classification
- MicroRNA MIR101 family
