DCC, ID (DCC, IGDCC1, Netrin receptor DCC, Colorectal cancer suppressor, Immunoglobulin superfamily DCC subclass member 1, Tumor suppressor protein DCC)

• Catalog number
  MBS6000986
• Price
  Please ask
• Size
  0,2 mL

• Other size
  please contact us to order other different size
• Description
  The receptors are ligand binding factors of type 1, 2 or 3 and protein-molecules that receive chemical-signals from outside a cell. When such chemical-signals couple or bind to a receptor, they cause some form of cellular/tissue-response, e.g. a change in the electrical-activity of a cell. In this sense, am olfactory receptor is a protein-molecule that recognizes and responds to endogenous-chemical signals, chemokinesor cytokines e.g. an acetylcholine-receptor recognizes and responds to its endogenous-ligand, acetylcholine. However, sometimes in pharmacology, the term is also used to include other proteins that are drug-targets, such as enzymes, transporters and ion-channels. Kinase, breast cancer tumor, HRAS like - suppressor protein make genetic suppression restoring the phenotype seen prior to the original background in biological pathways.

• Gene target
  DCC   DCC   IGDCC1   Netrin   receptor   DCC   Colorectal   cancer   suppressor   Immunoglobulin   superfamily   DCC   subclass   member   Tumor   suppressor   protein   DCC  
• Gene symbol
  DCC
• Short name
  DCC, ID (DCC, IGDCC1, Netrin receptor DCC, Colorectal cancer suppressor, Immunoglobulin superfamily DCC subclass member 1, Tumor suppressor protein DCC)
• Alternative name
  deleted in colorectal carcinoma, ID (deleted in colorectal carcinoma, IGDCC1, Netrin receptor deleted in colorectal carcinoma, Colorectal cancer suppressor, Immunoglobulin supergroup deleted in colorectal carcinoma subclass member 1, Tumor suppressor protein deleted in colorectal carcinoma)
• Alternative to gene target
  deleted in colorectal carcinoma, CRC18 and CRCR1 and IGDCC1 and MRMV1 and NTN1R1, DCC and IDBG-3511 and ENSG00000187323 and 1630, identical protein binding, Plasma membranes, Dcc and IDBG-157336 and ENSMUSG00000060534 and 13176
• Tissue
  tumor
• Disease
  cancer

Gene info

• Identity
  HGNC:2701
• Gene
  DCC
• Long gene name
  DCC netrin 1 receptor
• Synonyms gene name
  • deleted in colorectal carcinoma
• Synonyms
  • IGDCC1
  • NTN1R1
• Synonyms name
  • immunoglobulin superfamily, DCC subclass, member 1
• GenBank acession
  • X76132
• Locus
  18q21.2
• Discovery year
  1990-05-25
• Entrez gene record
  1630
• Pubmed identfication
  • 2294591
  • 24400119
• RefSeq identity
  • NM_005215
• Classification
  • Fibronectin type III domain containing
  • MicroRNA protein coding host genes
  • I-set domain containing
• VEGA ID
  OTTHUMG00000132698
• Locus Specific Databases
  • LRG_1107

MeSH Data

• Name
  Tumor Stem Cell Assay
• Concept
  Scope note: A cytologic technique for measuring the functional capacity of tumor stem cells by assaying their activity. It is used primarily for the in vitro testing of antineoplastic agents.
• Tree numbers
  • E01.370.225.500.383.910
  • E01.370.225.500.388.930
  • E05.200.500.383.910
  • E05.200.500.388.930
  • E05.242.383.910
  • E05.242.417.500
  • E05.337.550.200.800
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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