DARC (Duffy Antigen, Fy Glycoprotein, GpFy, Cell Adhesion Molecule 3, CADM3) (APC)

• Catalog number
  MBS600023
• Price
  Please ask
• Size
  5x100 Tests

• Products_type
  Antibody
• Products_short_name
  [DARC]
• Products_name_syn
  [Anti -DARC (Duffy Antigen, Fy Glycoprotein, GpFy, Cell Adhesion Molecule 3, CADM3) (APC)]
• Other_names
  [Duffy antigen/chemokine receptor isoform a; Duffy antigen/chemokine receptor; Duffy antigen/chemokine receptor; glycoprotein D; Fy glycoprotein; Duffy blood group antigen; plasmodium vivax receptor; atypical chemokine receptor 1; Duffy blood group, chemokine receptor; Duffy blood group, atypical chemokine receptor; Fy glycoprotein; GpFy; Glycoprotein D; Plasmodium vivax receptor]
• Other_gene_names
  [DARC; DARC; FY; Dfy; GPD; GpFy; ACKR1; CCBP1; CD234; WBCQ1; FY; GPD; GpFy]
• Clonality
  Monoclonal
• Clone
  [7H31]
• Reactivity
  Human
• Specificity
  Recognizes human DARC.
• Purity
  Affinity Purified Purified by Protein G affinity chromatography.
• Form
  Supplied as a liquid in PBS, 0.1% sodium azide. Labeled with APC.
• Storage_stability
  May be stored at 4 degree C before opening. DO NOT FREEZE! Stable at 4 degree C as an undiluted liquid. Dilute only prior to immediate use. Stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer. Freezing APC conjugates will result in a substantial loss of activity. APC conjugates are sensitive to light.
• Tested_application
  Flow Cytometry (FC/FACS)
• Description
  cell adhesion molecules play a role in cell growth and activation and are often identified by WB or ELISA as in the DARC (Duffy Antigen, Fy Glycoprotein, GpFy, Adhesion Molecule 3, CADM3) (APC). Antigens are peptides or recombinant or native dependent on the production method. For cells, cell lines and tissues in culture till half confluency. Whole adhesion and interacting molecules are  present in lysates used as reference for ELISA quantification of these molecules and their subunits.

• Gene target
  DARC   Duffy   Glycoprotein   GpFy   Adhesion   Molecule   CADM3   APC  
• Gene symbol
  CADM3-AS1, APC, ACKR1, CADM3
• Short name
  DARC (Duffy Antigen, Fy Glycoprotein, GpFy, Adhesion Molecule 3, CADM3) (APC)
• Technique
  antigen, antigenes
• Host
  Mouse
• Isotype
  IgG2a
• Label
  APC
• Alternative name
  Duffy blood group, chemokine receptor (Duffy protein, Fy Glycoprotein, GpFy, cellular Adhesion Molecule 3, cellular adhesion molecule 3) (adenomatous polyposis coli)
• Alternative technique
  antigenes
• Alternative to gene target
  adenomatous polyposis coli, BTPS2 and DP2 and DP2.5 and DP3 and GS and PPP1R46, APC and IDBG-37007 and ENSG00000134982 and 324, microtubule plus-end binding, nuclei, Apc and IDBG-134573 and ENSMUSG00000005871 and 11789, BT.25770 and IDBG-644937 and ENSBTAG00000018852 and 533233
• Tissue
  cell

Gene info

• Identity
  HGNC:40812
• Gene
  CADM3-AS1
• Long gene name
  CADM3 antisense RNA 1
• Synonyms
  • CTA-134P22.2
• Locus
  1q23.2
• Discovery year
  2014-02-01
• Entrez gene record
  100131825
• Classification
  • Antisense RNAs
• VEGA ID
  OTTHUMG00000037178

Gene info

• Identity
  HGNC:583
• Gene
  APC
• Long gene name
  APC regulator of WNT signaling pathway
• Synonyms gene name
  • adenomatosis polyposis coli
  • adenomatous polyposis coli
  • APC, WNT signaling pathway regulator
• Synonyms
  • DP2
  • DP3
  • DP2.5
  • PPP1R46
• Synonyms name
  • protein phosphatase 1, regulatory subunit 46
• GenBank acession
  • M74088
• Locus
  5q22.2
• Discovery year
  1986-01-01
• Entrez gene record
  324
• Pubmed identfication
  • 1651563
• RefSeq identity
  • NM_000038
• Classification
  • Protein phosphatase 1 regulatory subunits
  • Armadillo repeat containing
• VEGA ID
  OTTHUMG00000128806
• Locus Specific Databases
  • Adenomatous polyposis coli mutation database
  • UMD Locus Specific Databases
  • Global Variome shared LOVD
  • APC database at LOVD-China
  • LOVD - Leiden Open Variation Database
  • LRG_130

Gene info

• Identity
  HGNC:4035
• Gene
  ACKR1
• Long gene name
  atypical chemokine receptor 1 (Duffy blood group)
• Synonyms gene
  • FY
  • DARC
• Synonyms gene name
  • Duffy blood group
  • Duffy blood group, chemokine receptor
  • Duffy blood group, atypical chemokine receptor
• Synonyms
  • CCBP1
  • GPD
  • Dfy
  • CD234
• Synonyms name
  • atypical chemokine receptor 1
  • glycoprotein D
• GenBank acession
  • U01839
• Locus
  1q23.2
• Discovery year
  2001-06-22
• Entrez gene record
  2532
• Pubmed identfication
  • 8248172
  • 7663520
  • 16148
• RefSeq identity
  • NM_002036
• Classification
  • Atypical chemokine receptors
  • Blood group antigens
  • CD molecules
• VEGA ID
  OTTHUMG00000037182
• Locus Specific Databases
  • LRG_801

Gene info

• Identity
  HGNC:17601
• Gene
  CADM3
• Long gene name
  cell adhesion molecule 3
• Synonyms gene
  • IGSF4B
• Synonyms gene name
  • immunoglobulin superfamily, member 4B
• Synonyms
  • BIgR
  • FLJ10698
  • TSLL1
  • NECL1
  • SynCAM3
  • Necl-1
• Synonyms name
  • nectin-like 1
• GenBank acession
  • AY046418
• Locus
  1q23.2
• Discovery year
  2004-02-24
• Entrez gene record
  57863
• Pubmed identfication
  • 11536053
• RefSeq identity
  • NM_021189
• Classification
  • Nectins and nectin-like molecules
  • C2-set domain containing
  • V-set domain containing
• VEGA ID
  OTTHUMG00000037177

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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