Cyclooxygenase 1 (COX-1)

Products_type

Antibody
Products_short_name

[PGHS-1]
Products_name_syn

[Anti-PGH Synthase-1 [cyo-5]]
Other_names

[prostaglandin G/H synthase 1 isoform 2; Prostaglandin G/H synthase 1; prostaglandin G/H synthase 1; PGH synthase 1; cyclooxygenase-1; prostaglandin H2 synthase 1; prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase); Cyclooxygenase-1; COX-1; Prostaglandin H2 synthase 1; PGH synthase 1; PGHS-1; PHS 1; Prostaglandin-endoperoxide synthase 1]
Products_gene_name

[PGHS-1]
Other_gene_names

[PTGS1; PTGS1; COX1; COX3; PHS1; PCOX1; PES-1; PGHS1; PTGHS; PGG/HS; PGHS-1; COX1; COX-1; PGH synthase 1; PGHS-1; PHS 1]
Clonality

Monoclonal
Reactivity

Reacts with sheep, bovine, guinea pig, rabbit and human PGH Synthase. Does not react with rat, mouse or dog PGH Synthase.
Concentration

Approximately 50 mug IgG/mL.
Storage_stability

Stable for several weeks at 4 degree C, several months at -20 degree C, and indefinitely at -70 degree C. Avoid repeated freezing and thawing.
Tested_application

Immunoassay or immunohistochemical localization of Prostaglandin H Synthase.

Gene target

Cyclooxygenase COX-1
Gene symbol

PTGS1, MT-CO1, COX8A, IGHVII-1-1, MIR1-1, TRUND-NNN8-1, TRUND-NNN7-1, IGKV1OR2-1, MIR1289-1, MIR101-1
Short name

Cyclooxygenase 1 (COX-1)
Isotype

Mouse IgG2b.
Alternative name

Cyclooxygenase 1 (COX-1)

Identity

HGNC:9604
Gene

PTGS1
Long gene name

prostaglandin-endoperoxide synthase 1
Synonyms gene name
- prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase)
Synonyms
- COX1
- PGHS-1
- PTGHS
Synonyms name
- cyclooxygenase-1
GenBank acession
- M59979
Locus

9q33.2
Discovery year

1992-10-27
Entrez gene record

5742
Pubmed identfication
- 2512924
- 1907252
VEGA ID

OTTHUMG00000020605
Locus Specific Databases
- LRG_639

Identity

HGNC:7419
Gene

MT-CO1
Long gene name

mitochondrially encoded cytochrome c oxidase I
Synonyms gene
- MTCO1
Synonyms gene name
- cytochrome c oxidase I
Synonyms
- COX1
- COI
Locus

mitochondria
Discovery year

1989-10-12
Entrez gene record

4512
Pubmed identfication
- 7219534
RefSeq identity
- YP_003024028
Classification
- Mitochondrially encoded protein coding genes
- Mitochondrial complex IV: cytochrome c oxidase subunits

Identity

HGNC:2294
Gene

COX8A
Long gene name

cytochrome c oxidase subunit 8A
Synonyms gene
- COX8
Synonyms gene name
- cytochrome c oxidase subunit VIII
- cytochrome c oxidase subunit VIIIA (ubiquitous)
Synonyms
- COX8-2
- COX8L
- VIII-L
- COX
- VIII
GenBank acession
- J04823
Locus

11q13.1
Discovery year

1989-06-30
Entrez gene record

1351
Pubmed identfication
- 2543673
- 2847943
- 26685157
RefSeq identity
- NM_004074
Classification
- Mitochondrial complex IV: cytochrome c oxidase subunits
VEGA ID

OTTHUMG00000167785

Identity

HGNC:5670
Gene

IGHVII-1-1
Long gene name

immunoglobulin heavy variable (II)-1-1 (pseudogene)
Synonyms gene name
- immunoglobulin heavy variable (II)-1-1
- immunoglobulin heavy variable (II)-1-1 pseudogene
Synonyms
- IGHV(II)-1-1
GenBank acession
- AB019441
Locus

14q32.33
Discovery year

2000-04-17
Entrez gene record

28377
RefSeq identity
- NG_001019
Classification
- Immunoglobulin heavy locus at 14q32.33
VEGA ID

OTTHUMG00000152325

Identity

HGNC:5760
Gene

IGKV1OR2-1
Long gene name

immunoglobulin kappa variable 1/OR2-1 (pseudogene)
Synonyms gene
- IGKVPZ1
- IGKV1OR-1
Synonyms gene name
- immunoglobulin kappa variable 1/OR-1
- immunoglobulin kappa variable 1/OR-1 pseudogene
- immunoglobulin kappa variable 1/OR-1 (pseudogene)
Synonyms
- IGKV1/OR-1
- IGKV1/OR2-1
GenBank acession
- Z12367
Locus

2p11.1
Discovery year

2000-04-18
Entrez gene record

3531
Pubmed identfication
- 2853098
Classification
- Immunoglobulin kappa (IGK) orphons
VEGA ID

OTTHUMG00000155081