CXCR7 (C-X-C Chemokine Receptor 7, Chemokine Orphan Receptor 1, RDC-1) (PE)

• Catalog number
  MBS601840
• Price
  Please ask
• Size
  5x100 Tests

• Products_type
  Antibody
• Products_short_name
  [CXCR7]
• Products_name_syn
  [Anti -CXCR7 (C-X-C Chemokine Receptor 7, Chemokine Orphan Receptor 1, RDC-1) (PE)]
• Other_names
  [C-X-C chemokine receptor type 7; C-X-C chemokine receptor type 7; C-X-C chemokine receptor type 7; RDC-1; CXC-R7; CXCR-7; OTTHUMP00000164411; G protein-coupled receptor; chemokine orphan receptor 1; G-protein coupled receptor 159; G-protein coupled receptor RDC1 homolog; chemokine (C-X-C motif) receptor 7; Chemokine orphan receptor 1; G-protein coupled receptor 159; G-protein coupled receptor RDC1 homolog]
• Other_gene_names
  [CXCR7; CXCR7; RDC1; CMKOR1; GPR159; CMKOR1; GPR159; RDC1]
• Clonality
  Monoclonal
• Clone
  [7H134]
• Reactivity
  Human
• Specificity
  Recognizes human CXCR7. Reacts specifically as detected by Flow Cytometry with five distinct human CXCR7 transfectants, but not their respective parental lines. Also reacts with monocytes expression of CXCR7. Does not react with MCF-7 cells by Flow Cytometry, which have been reported to have surface-expressing CXCR7 using C8376-26. Due to the conflicting reports published, use of monoclonal C8376-25 may result in an underestimation of CXCR7 expression on certain cell types.
• Purity
  Affinity Purified Purified by Protein G affinity chromatography.
• Form
  Supplied as a liquid in PBS, 0.5% BSA, 0.1% sodium azide. Labeled with R-Phycoerythrin (PE).
• Storage_stability
  May be stored at 4 degree C before opening. DO NOT FREEZE! Stable at 4 degree C as an undiluted liquid. Stable for at least 12 months at 4 degree C. Freezing R-Phycoerythrin (PE) conjugates will result in a substantial loss of activity. PE conjugates are sensitive to light.
• Tested_application
  Flow Cytometry (FC/FACS)
• Description
  Chemokines, chemokine receptors, ligands , motif chemokines and cytokines are supplied by MyBioSource in 1. The receptors are ligand binding factors of type 1, 2 or 3 and protein-molecules that receive chemical-signals from outside a cell. When such chemical-signals couple or bind to a receptor, they cause some form of cellular/tissue-response, e.g. a change in the electrical-activity of a cell. In this sense, am olfactory receptor is a protein-molecule that recognizes and responds to endogenous-chemical signals, chemokinesor cytokines e.g. an acetylcholine-receptor recognizes and responds to its endogenous-ligand, acetylcholine. However, sometimes in pharmacology, the term is also used to include other proteins that are drug-targets, such as enzymes, transporters and ion-channels.

• Gene target
  CXCR7   C-X-C   Chemokine   Receptor   Chemokine   Orphan   Receptor   RDC-1  
• Gene symbol
  ACKR3, SMC4, PFDN4, FOS, JUN, TAC4, MYB, PCK1, ROS1
• Short name
  CXCR7 (C-X-C Chemokine Receptor 7, Chemokine Orphan Receptor 1, RDC-1) (PE)
• Host
  Mouse
• Isotype
  IgG2a
• Label
  PE
• Alternative name
  chemokine (C-X-C motif) receptor 7 (C-X-C Chemokine Receptor 7, Chemokine Orphan Receptor 1, RDC-1) (peroxidase)
• Alternative to gene target
  chemokine (C-X-C motif) receptor 7, CXCR7 and IDBG-84146 and ENSG00000144476 and 57007, C-X-C chemokine binding, Cell surfaces, Cxcr7 and IDBG-179969 and ENSMUSG00000044337 and 12778, CXCR7 and IDBG-642053 and ENSBTAG00000018424 and 509585

Gene info

• Identity
  HGNC:23692
• Gene
  ACKR3
• Long gene name
  atypical chemokine receptor 3
• Synonyms gene
  • CMKOR1
  • CXCR7
• Synonyms gene name
  • chemokine orphan receptor 1
  • chemokine (C-X-C motif) receptor 7
• Synonyms
  • RDC1
  • GPR159
• GenBank acession
  • BC008459
• Locus
  2q37.3
• Discovery year
  2003-12-01
• Entrez gene record
  57007
• Pubmed identfication
  • 16107333
  • 16148
• RefSeq identity
  • NM_020311
• Classification
  • Atypical chemokine receptors
• VEGA ID
  OTTHUMG00000133295

Gene info

• Identity
  HGNC:14013
• Gene
  SMC4
• Long gene name
  structural maintenance of chromosomes 4
• Synonyms gene
  • SMC4L1
• Synonyms gene name
  • SMC4 (structural maintenance of chromosomes 4, yeast)-like 1
  • SMC4 structural maintenance of chromosomes 4-like 1 (yeast)
• Synonyms
  • hCAP-C
  • CAP-C
• GenBank acession
  • AF092564
• Locus
  3q25.33
• Discovery year
  2001-02-22
• Entrez gene record
  10051
• Pubmed identfication
  • 9789013
  • 10319587
• Classification
  • Structural maintenance of chromosomes proteins
  • Condensin I subunits
  • Condensin II subunits
  • MicroRNA protein coding host genes
• VEGA ID
  OTTHUMG00000159006

Gene info

• Identity
  HGNC:8868
• Gene
  PFDN4
• Long gene name
  prefoldin subunit 4
• Synonyms gene name
  • prefoldin 4
• Synonyms
  • PFD4
  • C-1
  • C1
• GenBank acession
  • U41816
• Locus
  20q13.2
• Discovery year
  1998-08-06
• Entrez gene record
  5203
• Pubmed identfication
  • 9630229
  • 8744932
• RefSeq identity
  • NM_002623
• Classification
  • Prefoldin subunits
• VEGA ID
  OTTHUMG00000032775

Gene info

• Identity
  HGNC:3796
• Gene
  FOS
• Long gene name
  Fos proto-oncogene, AP-1 transcription factor subunit
• Synonyms gene name
  • v-fos FBJ murine osteosarcoma viral oncogene homolog
  • FBJ murine osteosarcoma viral oncogene homolog
• Synonyms
  • c-fos
  • AP-1
• GenBank acession
  • K00650
• Locus
  14q24.3
• Discovery year
  2001-06-22
• Entrez gene record
  2353
• Pubmed identfication
  • 16123044
  • 16055710
  • 15926923
• RefSeq identity
  • NM_005252
• Classification
  • Fos transcription factor family
  • Basic leucine zipper proteins
• VEGA ID
  OTTHUMG00000171774

Gene info

• Identity
  HGNC:6204
• Gene
  JUN
• Long gene name
  Jun proto-oncogene, AP-1 transcription factor subunit
• Synonyms gene name
  • v-jun avian sarcoma virus 17 oncogene homolog
  • jun oncogene
• Synonyms
  • c-Jun
  • AP-1
• GenBank acession
  • AY217548
• Locus
  1p32.1
• Discovery year
  1988-05-11
• Entrez gene record
  3725
• Pubmed identfication
  • 3194415
• RefSeq identity
  • NM_002228
• Classification
  • Basic leucine zipper proteins
  • Jun transcription factor family
• VEGA ID
  OTTHUMG00000008376

Gene info

• Identity
  HGNC:16641
• Gene
  TAC4
• Long gene name
  tachykinin precursor 4
• Synonyms gene name
  • tachykinin 4
• Synonyms
  • HK-1
  • Pptc
  • PPT-C
• Synonyms name
  • hemokinin
• GenBank acession
  • AF521560
• Locus
  17q21.33
• Discovery year
  2004-10-20
• Entrez gene record
  255061
• Pubmed identfication
  • 11062498
  • 12383518
• RefSeq identity
  • NM_170685
• Classification
  • Tachykinin precursors
• VEGA ID
  OTTHUMG00000161830

Gene info

• Identity
  HGNC:7545
• Gene
  MYB
• Long gene name
  MYB proto-oncogene, transcription factor
• Synonyms gene name
  • v-myb avian myeloblastosis viral oncogene homolog
• Synonyms
  • c-myb
• Locus
  6q23.3
• Discovery year
  2001-06-22
• Entrez gene record
  4602
• Pubmed identfication
  • 17599807
• Classification
  • Myb/SANT domain containing
• VEGA ID
  OTTHUMG00000015629
• Locus Specific Databases
  • The Globin Gene Server

Gene info

• Identity
  HGNC:8724
• Gene
  PCK1
• Long gene name
  phosphoenolpyruvate carboxykinase 1
• Synonyms gene name
  • phosphoenolpyruvate carboxykinase 1 (soluble)
• Synonyms
  • PEPCK-C
• Locus
  20q13.31
• Discovery year
  1990-09-10
• Entrez gene record
  5105
• Pubmed identfication
  • 1492743
• VEGA ID
  OTTHUMG00000032825

Gene info

• Identity
  HGNC:10261
• Gene
  ROS1
• Long gene name
  ROS proto-oncogene 1, receptor tyrosine kinase
• Synonyms gene name
  • v-ros avian UR2 sarcoma virus oncogene homolog 1
  • v-ros UR2 sarcoma virus oncogene homolog 1 (avian)
  • c-ros oncogene 1 , receptor tyrosine kinase
• Synonyms
  • MCF3
  • ROS
  • c-ros-1
• GenBank acession
  • M13599
• Locus
  6q22.1
• Discovery year
  1986-01-01
• Entrez gene record
  6098
• Pubmed identfication
  • 1611909
• Classification
  • Receptor tyrosine kinases
  • Fibronectin type III domain containing
• VEGA ID
  OTTHUMG00000016188
• Locus Specific Databases
  • LRG_997

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