Connexin 32 (Gap Junction Protein)

• Catalog number
  MBS439991
• Price
  Please ask
• Size
  0.02 mg (With BSA & Azide at 0.2mg/mL)

• Products_type
  Antibody
• Products_short_name
  [Connexin 32]
• Products_name_syn
  [Charcot Marie Tooth neuropathy X linked; CMTX; CMTX1; Connexin-32; Cx32; GAP junction 28kDa liver protein; Gap junction beta-1 protein; Gap junction protein beta 1 32kD; GJB1]
• Other_names
  [gap junction beta-1 protein; Gap junction beta-1 protein; gap junction beta-1 protein; gap junction protein beta 1; Connexin-32; Cx32; GAP junction 28 kDa liver protein]
• Products_gene_name
  [GJB1]
• Other_gene_names
  [GJB1; GJB1; CMTX; CX32; CMTX1; CX32; Cx32]
• Clonality
  Monoclonal
• Clone
  [M12.13]
• Reactivity
  Human, Mouse, Rat. Others not known.
• Specificity
  This Ab recognizes a protein of 27-32kDa, identified as Connexin 32. The connexin family of proteins forms hexameric complexes called connexons that facilitate movement of low molecular weight proteins between cells via gap junctions. Connexin proteins share a common topology of four transmembrane alpha-helical domains, two extracellular loops, a cytoplasmic loop and cytoplasmic N- and C-termini. Many of the key functional differences arise from specific amino-acid substitutions in the most highly conserved domains, the transmembrane and extracellular regions. Each of the approximately 20-connexin isoforms produces channels with distinct permeability and electrical and chemical sensitivities; therefore, one connexin usually cannot fully substitute for another.
• Form
  200ug/ml of Ab purified from Bioreactor Concentrate by Protein G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.
• Storage_stability
  Antibody with azide - store at 2 to 8 degree C. Antibody without azide - store at -20 to -80 degree C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
• Tested_application
  Immunofluorescence (IF), Flow Cytometry (FC/FACS), Western Blot (WB), Immunohistochemistry (IHC) Formalin

• Gene target
  Connexin   Gap   Junction   Protein  
• Gene symbol
  GJB1
• Short name
  Connexin 32 (Gap Junction Protein)
• Host
  Mouse
• Isotype
  IgG
• Alternative name
  Connexin 32 (Gap Junction Protein)

Gene info

• Identity
  HGNC:4283
• Gene
  GJB1
• Long gene name
  gap junction protein beta 1
• Synonyms gene
  • CMTX1
  • CMTX
• Synonyms gene name
  • gap junction protein, beta 1, 32kD (connexin 32, Charcot-Marie-Tooth neuropathy, X-linked)
  • gap junction protein, beta 1, 32kDa (connexin 32, Charcot-Marie-Tooth neuropathy, X-linked)
  • gap junction protein, beta 1, 32kDa (connexin 32)
  • gap junction protein, beta 1, 32kDa
• Synonyms
  • CX32
• Synonyms name
  • Charcot-Marie-Tooth neuropathy, X-linked
  • connexin 32
• GenBank acession
  • X04325
• Locus
  Xq13.1
• Discovery year
  1990-02-12
• Entrez gene record
  2705
• Pubmed identfication
  • 1319395
• RefSeq identity
  • NM_000166
• Classification
  • Gap junction proteins
• VEGA ID
  OTTHUMG00000021797
• Locus Specific Databases
  • Inherited Peripheral Neuropathies Mutation Database
  • LOVD GJB1 homepage
  • LRG_245

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