CNOT3 (KIAA0691, LENG2, NOT3, CCR4-NOT Transcription Complex Subunit 3, CCR4-associated Factor 3, Leukocyte Receptor Cluster Member 2)
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Catalog number
MBS648321
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Price
Please ask
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Size
5x0.1 mg
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Products_type
Antibody
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Products_short_name
[CNOT3]
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Products_name_syn
[Anti -CNOT3 (KIAA0691, LENG2, NOT3, CCR4-NOT Transcription Complex Subunit 3, CCR4-associated Factor 3, Leukocyte Receptor Cluster Member 2)]
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Other_names
[CCR4-NOT transcription complex subunit 3; CCR4-NOT transcription complex subunit 3; CCR4-NOT transcription complex subunit 3; CCR4-associated factor 3; leukocyte receptor cluster member 2; NOT3 (negative regulator of transcription 3, yeast) homolog; CCR4-NOT transcription complex, subunit 3; CCR4-associated factor 3; Leukocyte receptor cluster member 2]
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Other_gene_names
[CNOT3; CNOT3; NOT3; LENG2; NOT3H; KIAA0691; LENG2; NOT3]
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Clonality
Monoclonal
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Clone
[4B8]
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Reactivity
Human
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Specificity
Recognizes human CNOT3.
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Purity
Affinity Purified Purified by Protein A affinity chromatography.
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Form
Supplied as a liquid in PBS, pH 7.2.
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Storage_stability
May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
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Tested_application
ELISA (EL/EIA), Western Blot (WB), Immunofluorescence (IF)
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Description
Aplha, transcription related growth factors and stimulating factors or repressing nuclear factors are complex subunits of proteins involved in cell differentiation. Complex subunit associated factors are involved in hybridoma growth, Eosinohils, eritroid proliferation and derived from promotor binding stimulating subunits on the DNA binding complex. NFKB 105 subunit for example is a polypetide gene enhancer of genes in B cells. The receptors are ligand binding factors of type 1, 2 or 3 and protein-molecules that receive chemical-signals from outside a cell. When such chemical-signals couple or bind to a receptor, they cause some form of cellular/tissue-response, e.g. a change in the electrical-activity of a cell. In this sense, am olfactory receptor is a protein-molecule that recognizes and responds to endogenous-chemical signals, chemokinesor cytokines e.g. an acetylcholine-receptor recognizes and responds to its endogenous-ligand, acetylcholine. However, sometimes in pharmacology, the term is also used to include other proteins that are drug-targets, such as enzymes, transporters and ion-channels. The activation of transcription factor subunits is the first step of gene expression, in which a particular segment of DNA is copied into RNA (mRNA) by the enzyme RNA polymerases. Transcription factors, unites and elongations can be RNA and DNA nucleic acids, base pairs of nucleotides . Converting from DNA to RNA is made by enzymatic reactions. During transcription, a DNA sequence is read by an RNA polymerase, which produces a complementary, anti-parallel RNA strand called a primary transcript. Transcriptions are key functions in signal transduction pathways. Signaling ligand binding transcription factors play an important role in transduction cascades.
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Gene target
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Gene symbol
CNOT3, CNOT6, CCR4, RNA28S1, DUX1, DUX3, DUX5, TAS2R36
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Short name
CNOT3 (KIAA0691, LENG2, NOT3, CCR4-NOT Transcription Complex Subunit 3, CCR4-associated Factor 3, Leukocyte Receptor Cluster Member 2)
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Host
Mouse
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Isotype
IgG1,k
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Alternative name
CNOT3 (KIAA0691, LENG2, NOT3, chemokine (C-C motif) receptor 4-NOT Transcription aggregate functionnal sequence 3, chemokine (C-C motif) receptor 4-associated Factor 3, Leukocyte Receptor Cluster Member 2)
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Alternative to gene target
chemokine (C-C motif) receptor 4, CC-CKR-4 and CD194 and ChemR13 and CKR4 and CMKBR4 and HGCN:14099 and K5-5, CCR4 and IDBG-23908 and ENSG00000183813 and 1233, C-C chemokine receptor activity, Cell surfaces, Ccr4 and IDBG-203512 and ENSMUSG00000047898 and 12773, CCR4 and IDBG-644121 and ENSBTAG00000034883 and 100851774,408019
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Gene info
Gene info
Gene info
Gene info
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Identity
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Gene
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Long gene name
RNA, 28S ribosomal 1
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Synonyms name
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Locus
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Discovery year
2012-08-07
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Entrez gene record
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Classification
Gene info
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Identity
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Gene
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Long gene name
double homeobox 1
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Synonyms gene name
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GenBank acession
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Locus
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Discovery year
1999-12-01
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Entrez gene record
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Pubmed identfication
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RefSeq identity
Gene info
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Identity
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Gene
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Long gene name
double homeobox 3
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GenBank acession
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Locus
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Discovery year
1999-12-01
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Entrez gene record
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Pubmed identfication
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RefSeq identity
Gene info
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Identity
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Gene
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Long gene name
double homeobox 5
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GenBank acession
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Locus
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Discovery year
1999-12-01
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Entrez gene record
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Pubmed identfication
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RefSeq identity
Gene info
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