Chromogranin A/CHGA (Neuroendocrine Marker)

• Catalog number
  MBS439871
• Price
  Please ask
• Size
  5x0.1 mg (Without BSA & Azide at 1mg/mL)

• Products_type
  Antibody
• Products_short_name
  [Chromogranin A/CHGA]
• Products_name_syn
  [Beta-Granin; CGA; CHGA; Chromogranin A Parathyroid Secretory Protein 1; ER-37; Pancreastatin; Parastatin; Parathyroid Secretory Protein 1; Pituitary Secretory Protein I; SP-I; Vasostatin I or II]
• Other_names
  [chromogranin-A isoform 1 preproprotein; Chromogranin-A; chromogranin-A; chromogranin A; SL21]
• Products_gene_name
  [CHGA]
• Other_gene_names
  [CHGA; CHGA; CGA; CgA; SP-I]
• Clonality
  Monoclonal
• Clone
  [CHGA/1773R]
• Reactivity
  Human. Does not react with rat. Others not known.
• Specificity
  Chromogranin A is present in neuroendocrine cells throughout the body, including the neuroendocrine cells of the large and small intestine, adrenal medulla and pancreatic islets. It is an excellent marker for carcinoid tumors, pheochromocytomas, paragangliomas, and other neuroendocrine tumors. Co-expression of chromogranin A and neuron specific enolase (NSE) is common in neuroendocrine neoplasms. Reportedly, co-expression of certain keratins and chromogranin indicates neuroendocrine lineage. The presence of strong anti-chromogranin staining and absence of anti-keratin staining should raise the possibility of paraganglioma. The co-expression of chromogranin and NSE is typical of neuroendocrine neoplasms. Most pituitary adenomas and prolactinomas readily express chromogranin.
• Form
  200ug/ml of Ab purified by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.
• Storage_stability
  Antibody with azide - store at 2 to 8 degree C. Antibody without azide - store at -20 to -80 degree C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
• Tested_application
  Flow Cytometry (FC/FACS), Immunofluorescence (IF), Immunohistochemistry (IHC) Formalin

• Gene target
  Chromogranin   A/CHGA   Neuroendocrine  
• Gene symbol
  CHGA
• Short name
  Chromogranin A/CHGA (Neuroendocrine )
• Technique
  Component cell markers and DNA bp. markers are genetic markers er genes or DNA sequences with a known location on a chromosome that can be used to identify individuals or species. Protein markers in kDA.
• Host
  Rabbit
• Isotype
  IgG
• Alternative name
  Chromogranin A/CHGA (Neuroendocrine detection labelled)

Gene info

• Identity
  HGNC:1929
• Gene
  CHGA
• Long gene name
  chromogranin A
• Synonyms name
  • vasostatin
  • pancreastatin
  • parastatin
  • parathyroid secretory protein 1
• Locus
  14q32.12
• Discovery year
  2001-06-22
• Entrez gene record
  1113
• Pubmed identfication
  • 3403545
• RefSeq identity
  • NM_001275
• Classification
  • Neuropeptides
  • Granins
• VEGA ID
  OTTHUMG00000171225

Similar products