Chromogranin A / CHGA (Neuroendocrine Marker) Mouse Monoclonal Antibody

• Catalog number
  MBS439534
• Price
  Please ask
• Size
  5x0.1 mg (Without BSA & Azide at 1mg/mL)

• Products_type
  Antibody
• Products_short_name
  [Chromogranin A / CHGA]
• Products_name_syn
  [Beta-Granin; CGA; CHGA; Chromogranin A Parathyroid Secretory Protein 1; ER-37; Pancreastatin; Parastatin; Parathyroid Secretory Protein 1; Pituitary Secretory Protein I; SP-I; Vasostatin I or II]
• Other_names
  [chromogranin-A isoform 1 preproprotein; Chromogranin-A; chromogranin-A; chromogranin A; SL21]
• Products_gene_name
  [CHGA]
• Other_gene_names
  [CHGA; CHGA; CGA; CgA; SP-I]
• Clonality
  Monoclonal
• Clone
  [CGA/413 + CHGA/777 + CHGA/798]
• Reactivity
  Human, Monkey, Pig, Mouse, Rat
• Specificity
  Chromogranin A is present in neuroendocrine cells throughout the body, including the neuroendocrine cells of the large and small intestine, adrenal medulla and pancreatic islets. It is an excellent marker for carcinoid tumors, pheochromocytomas, paragangliomas, and other neuroendocrine tumors. Co-expression of chromogranin A and neuron specific enolase (NSE) is common in neuroendocrine neoplasms. Reportedly, co-expression of certain keratins and chromogranin indicates neuroendocrine lineage. The presence of strong anti-chromogranin staining and absence of anti-keratin staining should raise the possibility of paraganglioma. The co-expression of chromogranin and NSE is typical of neuroendocrine neoplasms. Most pituitary adenomas and prolactinomas readily express chromogranin.
• Form
  200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.
• Storage_stability
  Antibody with azide - store at 2 to 8 degree C. Antibody without azide - store at -20 to -80 degree C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
• Tested_application
  Flow Cytometry (FC/FACS), Immunofluorescence (IF), Immunohistochemistry (IHC) Formalin
• Properties
  If you buy Antibodies supplied by MyBioSource they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• About
  Monoclonals of this antigen are available in different clones. Each murine monoclonal anibody has his own affinity specific for the clone. Mouse monoclonal antibodies are purified protein A or G and can be conjugated to FITC for flow cytometry or FACS and can be of different isotypes.
• Test
  Mouse or mice from the Mus musculus species are used for production of mouse monoclonal antibodies or mabs and as research model for humans in your lab. Mouse are mature after 40 days for females and 55 days for males. The female mice are pregnant only 20 days and can give birth to 10 litters of 6-8 mice a year. Transgenic, knock-out, congenic and inbread strains are known for C57BL/6, A/J, BALB/c, SCID while the CD-1 is outbred as strain.
• Latin name
  Mus musculus
• French translation
  anticorps

• Gene target
  Chromogranin   CHGA   Neuroendocrine   Monoclonal  
• Gene symbol
  CHGA
• Short name
  Chromogranin A / CHGA (Neuroendocrine ) Mouse Monoclonal Antibody
• Technique
  Mouse monoclonal, Antibody, Mouse, antibodies against human proteins, antibodies for, Component cell markers and DNA bp. markers are genetic markers er genes or DNA sequences with a known location on a chromosome that can be used to identify individuals or species. Protein markers in kDA. Monoclonals or monoclonal antibodies, mouses, mouse monoclonals
• Host
  Mouse, Murine monoclonal antibodies or Mabs are often conjugated and the isotype is IgG.
• Isotype
  IgG
• Species
  Mouse, Mouses
• Alternative name
  Chromogranin A / CHGA (Neuroendocrine detection labelled) Mouse monoclonal (antibody to-)
• Alternative technique
  antibodies, murine

Gene info

• Identity
  HGNC:1929
• Gene
  CHGA
• Long gene name
  chromogranin A
• Synonyms name
  • vasostatin
  • pancreastatin
  • parastatin
  • parathyroid secretory protein 1
• Locus
  14q32.12
• Discovery year
  2001-06-22
• Entrez gene record
  1113
• Pubmed identfication
  • 3403545
• RefSeq identity
  • NM_001275
• Classification
  • Neuropeptides
  • Granins
• VEGA ID
  OTTHUMG00000171225

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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