Cholinergic Receptor, Nicotinic, alpha 7, Exons 5-10 (CHRFAM7A, CHRNA7 and FAM7A Family with Sequence Similarity 7A, Exons A-E Fusion, CHRNA7, CHRNA7-DR1, CHRNA7-FAM7A Fusion Protein, D-10, MGC120482, MGC120483)

• Catalog number
  MBS629073
• Price
  Please ask
• Size
  0.1 mg

• Products_type
  Antibody
• Products_short_name
  [Cholinergic Receptor, Nicotinic, alpha 7, Exons 5-10]
• Products_name_syn
  [Anti -Cholinergic Receptor, Nicotinic, alpha 7, Exons 5-10 (CHRFAM7A, CHRNA7 and FAM7A Family with Sequence Similarity 7A, Exons A-E Fusion, CHRNA7, CHRNA7-DR1, CHRNA7-FAM7A Fusion Protein, D-10, MGC120482, MGC120483)]
• Other_names
  [cholinergic receptor, nicotinic, alpha polypeptide 7; Neuronal acetylcholine receptor subunit alpha-7; neuronal acetylcholine receptor subunit alpha-7; OTTHUMP00000159615; a7 nicotinic acetylcholine receptor; alpha-7 nicotinic cholinergic receptor subunit; alpha 7 neuronal nicotinic acetylcholine receptor; cholinergic receptor, nicotinic, alpha polypeptide 7; neuronal acetylcholine receptor protein, alpha-7 chain; cholinergic receptor, nicotinic, alpha 7]
• Other_gene_names
  [CHRNA7; CHRNA7; NACHRA7; CHRNA7-2; NACHRA7]
• Clonality
  Polyclonal
• Reactivity
  Human
• Specificity
  Recognizes human CHRFAM7A.
• Purity
  Affinity Purified Purified by immunoaffinity chromatography.
• Form
  Supplied as a liquid in Tris, pH 7.3, 0.5% BSA, 0.02% sodium azide.
• Storage_stability
  May be stored at 4 degree C for short-term only. For long-term storage and to avoid repeated freezing and thawing, aliquot and store at -20 degree C. Aliquots are stable for at least 12 monthsat -20 degree C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
• Tested_application
  ELISA (EL/EIA)
• Description
  The Cholinergic Receptor, Nicotinic, alpha 7, Exons 5-10 (CHRFAM7A, CHRNA7 FAM7A Family with Sequence Similarity 7A, Exons A-E , CHRNA7, CHRNA7-DR1, CHRNA7-FAM7A Protein, D-10, MGC120482, MGC120483) is a α- or alpha protein sometimes glycoprotein present in blood. Fusion proteins or chimeric proteins are proteins created through the joining of two or more genes that originally coded for separate proteins. A GFP gene is often used as tag to a reporter gene. Fusion lentiverctors can be used as viral particles to produce proteins that carry for example a GFP tag. Antigen purification of recombinant fusion tag proteins is a frequent strategy using a Fralg tag. The receptors are ligand binding factors of type 1, 2 or 3 and protein-molecules that receive chemical-signals from outside a cell. When such chemical-signals couple or bind to a receptor, they cause some form of cellular/tissue-response, e.g. a change in the electrical-activity of a cell. In this sense, am olfactory receptor is a protein-molecule that recognizes and responds to endogenous-chemical signals, chemokinesor cytokines e.g. an acetylcholine-receptor recognizes and responds to its endogenous-ligand, acetylcholine. However, sometimes in pharmacology, the term is also used to include other proteins that are drug-targets, such as enzymes, transporters and ion-channels.

• Gene target
  Cholinergic   Receptor   Nicotinic   alpha   Exons   5-10   CHRFAM7A   CHRNA7   FAM7A   Family   with   Similarity   Exons   A-E   CHRNA7   CHRNA7-DR1   CHRNA7-FAM7A   Protein   D-10   MGC120482   MGC120483  
• Gene symbol
  CHRFAM7A, CHRNA7, IGHV5-10-1, PIRC49, SNORD115-10, SNORD116-10, IGHV3OR16-10, IGKV2OR2-10
• Short name
  Cholinergic Receptor, Nicotinic, alpha 7, Exons 5-10 (CHRFAM7A, CHRNA7 FAM7A Family with Sequence Similarity 7A, Exons A-E , CHRNA7, CHRNA7-DR1, CHRNA7-FAM7A Protein, D-10, MGC120482, MGC120483)
• Host
  Goat
• Isotype
  IgG
• Alternative name
  Cholinergic Receptor, Nicotinic, a 7, Exons 5-10 (CHRFAM7A, cholinergic receptor, nicotinic, a 7 (neuronal) and FAM7A family including Sequence Similarity 7A, Exons A-E Fusion, cholinergic receptor, nicotinic, a 7 (neuronal), cholinergic receptor, nicotinic, a 7 (neuronal)-DR1, cholinergic receptor, nicotinic, a 7 (neuronal)-FAM7A Fusion Protein, D-10, MGC120482, MGC120483)
• Alternative to gene target
  cholinergic receptor, nicotinic, alpha 7 (neuronal), CHRNA7-2 and NACHRA7, CHRNA7 and IDBG-5070 and ENSG00000175344 and 1139,89832, protein homodimerization activity, Cell surfaces, Chrna7 and IDBG-190675 and ENSMUSG00000030525 and 11441, CHRNA7 and IDBG-630821 and ENSBTAG00000015775 and 282178

Gene info

• Identity
  HGNC:15781
• Gene
  CHRFAM7A
• Long gene name
  CHRNA7 (exons 5-10) and FAM7A (exons A-E) fusion
• Synonyms gene name
  • CHRNA7 (cholinergic receptor, nicotinic, alpha 7, exons 5-10) and FAM7A (family with sequence similarity 7A, exons A-E) fusion
• Synonyms
  • D-10
  • CHRNA7-DR1
• GenBank acession
  • AF029838
• Locus
  15q13.2
• Discovery year
  2001-06-29
• Entrez gene record
  89832
• Pubmed identfication
  • 11829490
• RefSeq identity
  • NM_148911
• VEGA ID
  OTTHUMG00000175645

Gene info

• Identity
  HGNC:1960
• Gene
  CHRNA7
• Long gene name
  cholinergic receptor nicotinic alpha 7 subunit
• Synonyms gene name
  • cholinergic receptor, nicotinic, alpha polypeptide 7
  • cholinergic receptor, nicotinic, alpha 7 (neuronal)
  • cholinergic receptor, nicotinic alpha 7
• Synonyms name
  • acetylcholine receptor, nicotinic, alpha 7 (neuronal)
• GenBank acession
  • Z23141
• Locus
  15q13.3
• Discovery year
  1993-05-25
• Entrez gene record
  1139
• Pubmed identfication
  • 8188270
• Classification
  • Cholinergic receptors nicotinic subunits
• VEGA ID
  OTTHUMG00000129285

Gene info

• Identity
  HGNC:5661
• Gene
  IGHV5-10-1
• Long gene name
  immunoglobulin heavy variable 5-10-1
• Synonyms gene
  • IGHV5-A
• Synonyms gene name
  • immunoglobulin heavy variable 5-A (provisional, gene/pseudogene)
  • immunoglobulin heavy variable 5-A (provisional)
• Synonyms
  • IGHV5-a
• GenBank acession
  • X92227
• Locus
  14q32.33
• Discovery year
  2000-04-04
• Entrez gene record
  28386
• RefSeq identity
  • NG_001019
• Classification
  • Immunoglobulin heavy locus at 14q32.33
• VEGA ID
  OTTHUMG00000191143

Gene info

• Identity
  HGNC:37553
• Gene
  PIRC49
• Long gene name
  piwi-interacting RNA cluster 49
• Locus
  10
• Discovery year
  2009-11-05
• Entrez gene record
  100313929
• Pubmed identfication
  • 17881367
• Classification
  • Piwi-interacting RNA clusters

Gene info

• Identity
  HGNC:33029
• Gene
  SNORD115-10
• Long gene name
  small nucleolar RNA, C/D box 115-10
• Synonyms
  • HBII-52-10
• GenBank acession
  • AF250841
• Locus
  15q11.2
• Discovery year
  2007-02-15
• Entrez gene record
  100033447
• Pubmed identfication
  • 11106375
  • 11726556
• RefSeq identity
  • NR_003302.1
• Classification
  • Small nucleolar RNAs, C/D box

Gene info

• Identity
  HGNC:33076
• Gene
  SNORD116-10
• Long gene name
  small nucleolar RNA, C/D box 116-10
• Synonyms
  • HBII-85-10
• GenBank acession
  • AF250841
• Locus
  15q11.2
• Discovery year
  2007-02-15
• Entrez gene record
  100033422
• Pubmed identfication
  • 11106375
  • 11726556
• RefSeq identity
  • NR_003325
• Classification
  • Small nucleolar RNAs, C/D box

Gene info

• Identity
  HGNC:5634
• Gene
  IGHV3OR16-10
• Long gene name
  immunoglobulin heavy variable 3/OR16-10 (non-functional)
• Synonyms gene name
  • immunoglobulin heavy variable 3/OR16-10
• Synonyms
  • IGHV3/OR16-10
• GenBank acession
  • Z29607
• Locus
  16p11.2
• Discovery year
  2000-04-17
• Entrez gene record
  28306
• Classification
  • Immunoglobulin heavy (IGH) orphons
• VEGA ID
  OTTHUMG00000176446

Gene info

• Identity
  HGNC:5806
• Gene
  IGKV2OR2-10
• Long gene name
  immunoglobulin kappa variable 2/OR2-10 (pseudogene)
• Synonyms gene name
  • immunoglobulin kappa variable 2/OR2-10
  • immunoglobulin kappa variable 2/OR2-10 pseudogene
• Synonyms
  • IGKV2/OR2-10
• GenBank acession
  • X51886
• Locus
  2q11.2
• Discovery year
  2000-04-18
• Entrez gene record
  28855
• RefSeq identity
  • NG_011661
• Classification
  • Immunoglobulin kappa (IGK) orphons

MeSH Data

• Name
  Sequence Analysis, DNA
• Concept
  Scope note: A multistage process that includes cloning, physical mapping, subcloning, determination of the DNA SEQUENCE, and information analysis.
• Tree numbers
  • E05.393.760.700
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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