CD89 (Fc alpha R, FCAR, Immunoglobulin alpha Fc Receptor, IgA Fc Receptor)

• Catalog number
  MBS605531
• Price
  Please ask
• Size
  5x0.2 mg

• Products_type
  Antibody
• Products_short_name
  [CD89]
• Products_name_syn
  [Anti -CD89 (Fc alpha R, FCAR, Immunoglobulin alpha Fc Receptor, IgA Fc Receptor)]
• Clonality
  Monoclonal
• Clone
  [10B2126]
• Reactivity
  Human
• Specificity
  Recognizes human CD89 cell surface antigen, a 50-75kD cell surface glycoprotein that is also known as the IgA receptor (Fc alpha R).
• Purity
  Purified Purified
• Form
  Supplied as a liquid in PBS, pH 7.4, 0.09% sodium azide.
• Storage_stability
  May be stored at 4 degree C for short-term only. For long-term storage and to avoid repeated freezing and thawing, add sterile 40-50% glycerol, aliquot and store at -20 degree C. Aliquots are stable for at least 12 months at -20 degree C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
• Tested_application
  ELISA (EL/EIA), Western Blot (WB), Immunoprecipitation (IP), Flow Cytometry (FC/FACS)
• Description
  The CD89 (Fc alpha R, FCAR, Immunoglobulin alpha Fc Receptor, IgA Fc Receptor) is a α- or alpha protein sometimes glycoprotein present in blood. The receptors are ligand binding factors of type 1, 2 or 3 and protein-molecules that receive chemical-signals from outside a cell. When such chemical-signals couple or bind to a receptor, they cause some form of cellular/tissue-response, e.g. a change in the electrical-activity of a cell. In this sense, am olfactory receptor is a protein-molecule that recognizes and responds to endogenous-chemical signals, chemokinesor cytokines e.g. an acetylcholine-receptor recognizes and responds to its endogenous-ligand, acetylcholine. However, sometimes in pharmacology, the term is also used to include other proteins that are drug-targets, such as enzymes, transporters and ion-channels.
• Properties
  Immunoglobulin A (IgA, also referred to as sIgA) is an antibody that plays a critical role in immune function in the mucous membranes. More IgA is produced in mucosal linings than all other types of antibody combined. Examples are EMA, ACA ELISA test kits and for diagnostic detection the IgA of Anti-Beta-2 Glycoprotein 1; β2-Glycoprotein 1 Antibodies; Beta 2GP1 Ab, Beta-2 Glycoprotein 1 Antibodies IgG, IgM, and IgAs.

• Gene target
  CD89   alpha   FCAR   Immunoglobulin   alpha   Receptor   Receptor  
• Gene symbol
  FCAR
• Short name
  CD89 (Fc alpha R, FCAR, Immunoglobulin alpha Fc Receptor, IgA Fc Receptor)
• Technique
  IgA, FC, IgAs
• Host
  Mouse
• Isotype
  IgG1, IgA
• Alternative name
  CD89 (fragment c a R, fragment c fragment on Immunoglobulin A, receptor to measure, Immunoglobulin a fragment c Receptor, Immunoglobulin A fragment c Receptor)
• Alternative technique
  immunoglobulin-a
• Alternative to gene target
  Fc fragment of IgA, receptor for, CD89, FCAR and IDBG-69662 and ENSG00000186431 and 2204, IgA binding, Extracellular, FCAR and IDBG-641994 and ENSBTAG00000021647 and 503555

Gene info

• Identity
  HGNC:3608
• Gene
  FCAR
• Long gene name
  Fc fragment of IgA receptor
• Synonyms gene name
  • Fc fragment of IgA, receptor for
• Synonyms
  • CD89
• GenBank acession
  • X54150
• Locus
  19q13.42
• Discovery year
  1991-06-06
• Entrez gene record
  2204
• Pubmed identfication
  • 1577457
• RefSeq identity
  • NM_002000
• Classification
  • Immunoglobulin like domain containing
  • CD molecules
• VEGA ID
  OTTHUMG00000065936

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