CD28
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Catalog numberMBS438024
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Price:
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Size0.02 mg (With BSA & Azide at 0.2mg/mL)
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Products_typeAntibody
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Products_short_name[CD28]
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Products_name_syn[T-cell-specific surface glycoprotein CD28; Tp44]
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Other_names[T-cell-specific surface glycoprotein CD28 isoform 2; T-cell-specific surface glycoprotein CD28; T-cell-specific surface glycoprotein CD28; CD28 antigen; CD28 molecule; TP44; CD_antigen: CD28]
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Products_gene_name[CD28]
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Other_gene_names[CD28; CD28; Tp44]
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ClonalityMonoclonal
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Clone[C28/77]
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ReactivityHuman.
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SpecificityRecognizes a glycoprotein of 44-88kDa, which is identified as CD28. It is the critical T-cell co-stimulatory receptor which provides to the cell the important second activation signal by binding CD80 and CD86 that are expressed by antigen presenting cells. Besides its co-stimulation role, CD28 functions in preventing T-cells from anergic hyporesponsive state or from undergoing premature apoptotic cell death. CD28 is also expressed on human fetal NK cells and some NK cell lines, whereas on murine NK cells the CD28 expression is much broader.
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Form200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.
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Storage_stabilityStore at 2 to 8 degree C. Antibody is stable for 24 months.
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Tested_applicationELISA (EIA), Flow Cytometry (FC/FACS), Immunofluorescence (IF), Functional Studies, Immunoprecipitation (IP), Immunohistology (IH)
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Gene target
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Gene symbolCD28
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Short nameCD28
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HostMouse
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IsotypeIgG1, kappa
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Alternative nameCD28 molecule
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Alternative to gene targetCD28 molecule, Tp44, CD28 and IDBG-79183 and ENSG00000178562 and 940, identical protein binding, Cell surfaces, Cd28 and IDBG-159608 and ENSMUSG00000026012 and 12487, CD28 and IDBG-643371 and ENSBTAG00000007445 and 281050
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Gene info
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Identity
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Gene
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Long gene nameCD28 molecule
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Synonyms gene name
- CD28 antigen (Tp44)
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Synonyms name
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GenBank acession
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Locus
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Discovery year1988-05-11
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- CD molecules
- Ig-like cell adhesion molecule family
- V-set domain containing
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VEGA ID