CD2

• Catalog number
  MBS438496
• Price
  Please ask
• Size
  0.02 mg (With BSA & Azide at 0.2mg/mL)

• Products_type
  Antibody
• Products_short_name
  [CD2]
• Products_name_syn
  [Erythrocyte receptor; LFA-2; LFA-3 receptor; Ly-37; Lymphocyte function antigen 2; Rosette receptor; SRBC; T-cell surface antigen CD2; T-cell surface antigen T11/Leu-5; T11]
• Other_names
  [T-cell surface antigen CD2; T-cell surface antigen CD2; T-cell surface antigen CD2; LFA-3 receptor; rosette receptor; erythrocyte receptor; lymphocyte-function antigen-2; T-cell surface antigen T11/Leu-5; CD2 antigen (p50), sheep red blood cell receptor; CD2 molecule; Erythrocyte receptor; LFA-2; LFA-3 receptor; Rosette receptor; T-cell surface antigen T11/Leu-5; CD_antigen: CD2]
• Products_gene_name
  [CD2]
• Other_gene_names
  [CD2; CD2; T11; SRBC; LFA-2; SRBC]
• Clonality
  Monoclonal
• Clone
  [UMCD2]
• Reactivity
  Human.
• Specificity
  CD2 interacts through its amino-terminal domain with the extracellular domain of CD58 (also designated CD2 ligand) to mediate cell adhesion. CD2/CD58 binding can enhance antigen-specific T cell activation. CD2 is a transmembrane glycoprotein that is expressed on peripheral blood T lymphocytes, NK cells and thymocytes. CD58 is a heavily glycosylated protein with a broad tissue distribution in hematopoietic and other cells, including endothelium. Interaction between CD2 and its counter receptor LFA3 (CD58) on opposing cells optimizes immune system recognition, thereby facilitating communication between helper T lymphocytes and antigen-presenting cells, as well as between cytolytic effectors and target cells.
• Form
  200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.
• Storage_stability
  Store at 2 to 8 degree C. Antibody is stable for 24 months.
• Tested_application
  ELISA (EIA), Functional Studies, Flow Cytometry (FC/FACS), Immunofluorescence (IF), Western Blot (WB), Immunoprecipitation (IP), Immunohistology (IH)

• Gene target
  CD2  
• Gene symbol
  CD2
• Short name
  CD2
• Host
  Mouse
• Isotype
  IgG2a, kappa
• Alternative name
  CD2 molecule
• Alternative to gene target
  CD2 molecule, LFA-2 and SRBC and T11, CD2 and IDBG-101417 and ENSG00000116824 and 914, protein homodimerization activity, Extracellular, Cd2 and IDBG-179684 and ENSMUSG00000027863 and 12481, CD2 and IDBG-634458 and ENSBTAG00000017256 and 497022

Gene info

• Identity
  HGNC:1639
• Gene
  CD2
• Long gene name
  CD2 molecule
• Synonyms gene
  • SRBC
• Synonyms gene name
  • CD2 antigen (p50), sheep red blood cell receptor
• GenBank acession
  • BC033583
• Locus
  1p13.1
• Discovery year
  1986-01-01
• Entrez gene record
  914
• Pubmed identfication
  • 2437578
• RefSeq identity
  • NM_001767
• Classification
  • CD molecules
  • Ig-like cell adhesion molecule family
  • C2-set domain containing
  • V-set domain containing
• VEGA ID
  OTTHUMG00000022750

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