CD178, Low Endotoxin (Apt1lg1, CD95 Ligand, CD95L, CD95-L, Fas Antigen Ligand, Fas Ligand, Faslg, Fasl, Fas-L, gld, Tumor Necrosis Factor Ligand Superfamily Member 6, Tnfsf6)

• Catalog number
  MBS6009772
• Price
  Please ask
• Size
  0,5 mg

• Other size
  please contact us to order other different size
• Description
  Antigens are peptides or recombinant or native dependent on the production method. Aplha, transcription related growth factors and stimulating factors or repressing nuclear factors are complex subunits of proteins involved in cell differentiation. Complex subunit associated factors are involved in hybridoma growth, Eosinohils, eritroid proliferation and derived from promotor binding stimulating subunits on the DNA binding complex. NFKB 105 subunit for example is a polypetide gene enhancer of genes in B cells. FAS ligand and other ligands are binding to the receptor for signaling pathways for example in apoptosis or JNK signaling. Receptor agonists are often tested for drug development.

• Gene target
  CD178   Endotoxin   Apt1lg1   CD95   Ligand   CD95L   CD95-L   Fas   Ligand   Fas   Ligand   Faslg   Fasl   Fas-L   gld   Tumor   Necrosis   Factor   Ligand   Superfamily   Member   Tnfsf6  
• Gene symbol
  FAS, FASLG, CPT1A, POM121L2, L3MBTL2, CLDN10, RPL32P1, FABP1, COX7A2, NFIA
• Short name
  CD178, Endotoxin (Apt1lg1, CD95 Ligand, CD95L, CD95-L, Fas Antigen Ligand, Fas Ligand, Faslg, Fasl, Fas-L, gld, Tumor Necrosis Factor Ligand Superfamily Member 6, Tnfsf6)
• Technique
  antigen, antigenes
• Alternative name
  CD178, Low Endotoxin (Apt1lg1, CD95 Ligand, CD95L, CD95-L, Fas (tumor necrosis factor receptor superfamily, member 6) protein Ligand, Fas (tumor necrosis factor receptor superfamily, member 6) Ligand, Fas (tumor necrosis factor receptor superfamily, member 6) ligand (tumor necrosis factor superfamily, member 6), Fasl, Fas (tumor necrosis factor receptor superfamily, member 6)-L, gld, Tumor Necrosis Factor Ligand supergroup Member 6, Tnfsf6)
• Alternative technique
  antigenes
• Alternative to gene target
  Fas (TNF receptor superfamily, member 6), ALPS1A and APO-1 and APT1 and CD95 and FAS1 and FASTM and TNFRSF6, FAS and IDBG-81669 and ENSG00000026103 and 355, identical protein binding, nuclei, Fas and IDBG-159577 and ENSMUSG00000024778 and 14102, FAS and IDBG-637356 and ENSBTAG00000010785 and 282488
• Tissue
  tumor

Gene info

• Identity
  HGNC:11920
• Gene
  FAS
• Long gene name
  Fas cell surface death receptor
• Synonyms gene
  • FAS1
  • APT1
  • TNFRSF6
• Synonyms gene name
  • tumor necrosis factor receptor superfamily, member 6
  • Fas (TNF receptor superfamily, member 6)
• Synonyms
  • CD95
  • APO-1
• Synonyms name
  • TNF receptor superfamily member 6
• GenBank acession
  • M67454
• Locus
  10q23.31
• Discovery year
  1992-06-25
• Entrez gene record
  355
• Pubmed identfication
  • 1385299
  • 1385309
• Classification
  • Tumor necrosis factor receptor superfamily
  • Death inducing signaling complex
  • CD molecules
• VEGA ID
  OTTHUMG00000018701
• Locus Specific Databases
  • Autoimmune Lymphoproliferative Syndrome Database (ALPSbase): Database of mutations causing human ALPS
  • LOVD at NCBI
  • LRG_134

Gene info

• Identity
  HGNC:11936
• Gene
  FASLG
• Long gene name
  Fas ligand
• Synonyms gene
  • APT1LG1
  • TNFSF6
• Synonyms gene name
  • tumor necrosis factor (ligand) superfamily, member 6
  • Fas ligand (TNF superfamily, member 6)
• Synonyms
  • FasL
  • CD178
• GenBank acession
  • U11821
• Locus
  1q24.3
• Discovery year
  1994-12-09
• Entrez gene record
  356
• Pubmed identfication
  • 7826947
  • 9022072
• Classification
  • Tumor necrosis factor superfamily
  • Death inducing signaling complex
  • CD molecules
• VEGA ID
  OTTHUMG00000034841
• Locus Specific Databases
  • FASLGbase: Mutation registry for Autoimmune lymphoproliferative syndrome, type 1B (ALPS1B) (previously known as TNFSF6base)
  • LRG_58

Gene info

• Identity
  HGNC:2328
• Gene
  CPT1A
• Long gene name
  carnitine palmitoyltransferase 1A
• Synonyms gene
  • CPT1
• Synonyms gene name
  • carnitine palmitoyltransferase 1A (liver)
• Synonyms
  • CPT1-L
  • L-CPT1
• GenBank acession
  • L39211
• Locus
  11q13.3
• Discovery year
  1995-05-30
• Entrez gene record
  1374
• Pubmed identfication
  • 7892212
  • 9070950
• RefSeq identity
  • NM_001876
• VEGA ID
  OTTHUMG00000167892

Gene info

• Identity
  HGNC:13973
• Gene
  POM121L2
• Long gene name
  POM121 transmembrane nucleoporin like 2
• Synonyms gene name
  • POM121 membrane glycoprotein-like 2 (rat)
  • POM121 membrane glycoprotein-like 2
  • POM121 transmembrane nucleoporin-like 2
• Synonyms
  • POM121-L
• GenBank acession
  • AL021808
• Locus
  6p22.1
• Discovery year
  2001-07-20
• Entrez gene record
  94026
• RefSeq identity
  • NM_033482
• VEGA ID
  OTTHUMG00000014475

Gene info

• Identity
  HGNC:18594
• Gene
  L3MBTL2
• Long gene name
  L3MBTL histone methyl-lysine binding protein 2
• Synonyms gene name
  • l(3)mbt-like 2 (Drosophila)
  • L3MBTL2, polycomb repressive complex 1 subunit
• Synonyms
  • H-l(3)mbt-l
  • DKFZP761I141
  • dJ756G23.3
• GenBank acession
  • AJ305226
• Locus
  22q13.2
• Discovery year
  2002-04-29
• Entrez gene record
  83746
• Pubmed identfication
  • 11682070
  • 21596310
• RefSeq identity
  • NM_031488
• Classification
  • MBT domain containing
• VEGA ID
  OTTHUMG00000150942

Gene info

• Identity
  HGNC:2033
• Gene
  CLDN10
• Long gene name
  claudin 10
• Synonyms
  • OSP-L
  • CPETRL3
• GenBank acession
  • U89916
• Locus
  13q32.1
• Discovery year
  1999-01-22
• Entrez gene record
  9071
• Pubmed identfication
  • 18025272
• RefSeq identity
  • NM_006984
• Classification
  • Claudins
• VEGA ID
  OTTHUMG00000017217

Gene info

• Identity
  HGNC:10339
• Gene
  RPL32P1
• Long gene name
  ribosomal protein L32 pseudogene 1
• Synonyms gene
  • RPL32P
• Synonyms gene name
  • ribosomal protein L32 pseudogene
• Synonyms
  • RPL32-L
• GenBank acession
  • X02228
• Locus
  6p21.32
• Discovery year
  2009-03-01
• Entrez gene record
  6163
• Pubmed identfication
  • 3866218
  • 19123937
• RefSeq identity
  • NG_000869
• VEGA ID
  OTTHUMG00000031191

Gene info

• Identity
  HGNC:3555
• Gene
  FABP1
• Long gene name
  fatty acid binding protein 1
• Synonyms gene name
  • fatty acid binding protein 1, liver
• Synonyms
  • L-FABP
• GenBank acession
  • M10617
• Locus
  2p11.2
• Discovery year
  2001-06-22
• Entrez gene record
  2168
• Pubmed identfication
  • 3012800
  • 17698986
• RefSeq identity
  • NM_001443
• Classification
  • Fatty acid binding protein family
• VEGA ID
  OTTHUMG00000130312

Gene info

• Identity
  HGNC:2288
• Gene
  COX7A2
• Long gene name
  cytochrome c oxidase subunit 7A2
• Synonyms gene name
  • cytochrome c oxidase subunit VIIa polypeptide 2 (liver)
• Synonyms
  • COXVIIa-L
  • COX7AL
• GenBank acession
  • X15822
• Locus
  6q14.1
• Discovery year
  1992-11-25
• Entrez gene record
  1347
• Pubmed identfication
  • 1327965
  • 9202412
• RefSeq identity
  • NM_001865
• Classification
  • Mitochondrial complex IV: cytochrome c oxidase subunits
• VEGA ID
  OTTHUMG00000015049

Gene info

• Identity
  HGNC:7784
• Gene
  NFIA
• Long gene name
  nuclear factor I A
• Synonyms gene name
  • nuclear factor I/A
• Synonyms
  • NFI-L
  • KIAA1439
• GenBank acession
  • U07809
• Locus
  1p31.3
• Discovery year
  1995-03-09
• Entrez gene record
  4774
• Pubmed identfication
  • 7590749
• RefSeq identity
  • NM_005595
• Classification
  • Nuclear factor I family
• VEGA ID
  OTTHUMG00000008618

MeSH Data

• Name
  Tumor Stem Cell Assay
• Concept
  Scope note: A cytologic technique for measuring the functional capacity of tumor stem cells by assaying their activity. It is used primarily for the in vitro testing of antineoplastic agents.
• Tree numbers
  • E01.370.225.500.383.910
  • E01.370.225.500.388.930
  • E05.200.500.383.910
  • E05.200.500.388.930
  • E05.242.383.910
  • E05.242.417.500
  • E05.337.550.200.800
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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