CD137, Human IgG1 Fc Fusion Protein (FITC) (4-1BB, 4-1BB Ligand Receptor, CD137 Antigen, CDw137, ILA, T cell Antigen 4-1BB Homolog, T cell Antigen ILA, Tumor Necrosis Factor Receptor Superfamily Member 9, TNFRSF9)
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Catalog number
MBS635140
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Price
Please ask
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Size
50 Tests
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Other size
please contact us to order other different size
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Description
Antigens are peptides or recombinant or native dependent on the production method. For cells, cell lines and tissues in culture till half confluency. Aplha, transcription related growth factors and stimulating factors or repressing nuclear factors are complex subunits of proteins involved in cell differentiation. Complex subunit associated factors are involved in hybridoma growth, Eosinohils, eritroid proliferation and derived from promotor binding stimulating subunits on the DNA binding complex. NFKB 105 subunit for example is a polypetide gene enhancer of genes in B cells. Fusion proteins or chimeric proteins are proteins created through the joining of two or more genes that originally coded for separate proteins. A GFP gene is often used as tag to a reporter gene. Fusion lentiverctors can be used as viral particles to produce proteins that carry for example a GFP tag. Antigen purification of recombinant fusion tag proteins is a frequent strategy using a Fralg tag. FAS ligand and other ligands are binding to the receptor for signaling pathways for example in apoptosis or JNK signaling. Receptor agonists are often tested for drug development. The receptors are ligand binding factors of type 1, 2 or 3 and protein-molecules that receive chemical-signals from outside a cell. When such chemical-signals couple or bind to a receptor, they cause some form of cellular/tissue-response, e.g. a change in the electrical-activity of a cell. In this sense, am olfactory receptor is a protein-molecule that recognizes and responds to endogenous-chemical signals, chemokinesor cytokines e.g. an acetylcholine-receptor recognizes and responds to its endogenous-ligand, acetylcholine. However, sometimes in pharmacology, the term is also used to include other proteins that are drug-targets, such as enzymes, transporters and ion-channels.
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Properties
This MyBioSource Fluorescein isothiocyanate (FITC) antibody is currently after some BD antibodies the most commonly used fluorescent dye for FACS. When excited at 488 nanometers, FITC has a green emission that's usually collected at 530 nanometers, the FL1 detector of a FACSCalibur or FACScan. FITC has a high quantum yield (efficiency of energy transfer from absorption to emission fluorescence) and approximately half of the absorbed photons are emitted as fluorescent light. For fluorescent microscopy applications, the 1 FITC is seldom used as it photo bleaches rather quickly though in flow cytometry applications, its photo bleaching effects are not observed due to a very brief interaction at the laser intercept. MyBioSource FITC is highly sensitive to pH extremes. Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
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Conjugation
Anti-FITC Antibody
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Gene target
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Gene symbol
TNFRSF9, TNFSF9, MIR1302-4, PIRC18, PIRC16, SNORD114-4, MIR941-4, IGKV2OR2-4
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Short name
CD137, IgG1 Fc Protein (FITC) (4-1BB, 4-1BB Ligand Receptor, CD137 Antigen, CDw137, ILA, T Antigen 4-1BB Homolog, T Antigen ILA, Tumor Necrosis Factor Receptor Superfamily Member 9, TNFRSF9)
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Technique
antigen, FITC, FC, antigenes, Fluorescein
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Isotype
IgG1
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Label
FITC
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Species
Human, Humans
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Alternative name
CD137, H. sapiens IgG1 fragment c Fusion Protein (fluorecein) (4-1BB, 4-1BB Ligand Receptor, CD137 protein, CDw137, ILA, T cellular protein 4-1BB Homolog, T cellular protein ILA, Tumor Necrosis Factor Receptor supergroup Member 9, tumor necrosis factor receptor superfamily, member 9)
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Alternative technique
antigenes, fluorescine
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Alternative to gene target
tumor necrosis factor receptor superfamily, member 9, 4-1BB and CD137 and CDw137 and ILA, TNFRSF9 and IDBG-88268 and ENSG00000049249 and 3604, cytokine binding, Extracellular, Tnfrsf9 and IDBG-205902 and ENSMUSG00000028965 and 21942, BT.49346 and IDBG-633668 and ENSBTAG00000003313 and 520341
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Tissue
cell, tumor
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Gene info
Gene info
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Identity
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Gene
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Long gene name
TNF superfamily member 9
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Synonyms gene name
- tumor necrosis factor (ligand) superfamily, member 9
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year
1998-12-04
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Tumor necrosis factor superfamily
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VEGA ID
Gene info
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Identity
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Gene
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Long gene name
microRNA 1302-4
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Synonyms gene
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Synonyms
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Locus
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Discovery year
2008-11-03
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Entrez gene record
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RefSeq identity
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Classification
Gene info
Gene info
Gene info
Gene info
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Identity
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Gene
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Long gene name
microRNA 941-4
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Synonyms gene
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Synonyms
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Locus
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Discovery year
2007-10-24
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Entrez gene record
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RefSeq identity
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Classification
Gene info
MeSH Data
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Name
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Concept
Scope note:
Test for tissue antigen using either a direct method, by conjugation of antibody with fluorescent dye (FLUORESCENT ANTIBODY TECHNIQUE, DIRECT) or an indirect method, by formation of antigen-antibody complex which is then labeled with fluorescein-conjugated anti-immunoglobulin antibody (FLUORESCENT ANTIBODY TECHNIQUE, INDIRECT). The tissue is then examined by fluorescence microscopy.
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Tree numbers
- E01.370.225.500.607.512.240
- E01.370.225.750.551.512.240
- E05.200.500.607.512.240
- E05.200.750.551.512.240
- E05.478.583.375
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Qualifiers
ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data
Product images
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