CA19-9/Sialyl Lewisa (GI Tumor Marker) Recombinant Rabbit Monoclonal Antibody [Clone CA19.9/1390R]
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Products_type
Antibody
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Products_short_name
[CA19-9/Sialyl Lewisa (GI Tumor Marker)]
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Products_name_syn
[CA19.9; Ovarian tumor antigen; Pancreatic tumor antigen; Sialyl Lewis a]
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Products_gene_name
[CA19-9]
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Clone
[CA19.9/1390R]
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Reactivity
Human
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Specificity
CA19-9, a carbohydrate epitope expressed on a high MW (>400kDa) mucin glycoprotein, is a sialyl Lewisa structure which is synthesized from type 1 blood group precursor chains and is present in individuals expressing the Lewisa and/or Lewisb blood group antigens. In normal tissues, sialyl Lewisa antigen is present in ductal epithelium of the breast, kidney, salivary gland, and sweat glands. Its expression is greatly enhanced in serum as well as in the majority of tumor cells in gastrointestinal (GI) carcinomas, including adenocarcinomas of the stomach, intestine, and pancreas. Preoperative elevated CA19-9 levels in patients with stage I pancreatic carcinoma decrease to normal values following surgery. When used serially, CA19-9 can predict recurrence of disease prior to radiographic or clinical findings. This MAb is excellent for staining of formalin-fixed, paraffin-embedded tissues.
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Form
200ug/ml of Ab purified by Protein A column. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA and Azide at 1.0mg/ml.
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Tested_application
Flow Cytometry (FC/FACS); Immunofluorescence (IF); Immunohistochemistry (IHC)
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Properties
If you buy Antibodies supplied by MyBioSource they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
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About
Monoclonals of this antigen are available in different clones. Each murine monoclonal anibody has his own affinity specific for the clone. Mouse monoclonal antibodies are purified protein A or G and can be conjugated to FITC for flow cytometry or FACS and can be of different isotypes. Rabbits are used for polyclonal antibody production by MyBioSource. Rabbit antibodies are very stable and can be stored for several days at room temperature. MyBioSource adds sodium azide and glycerol to enhance the stability of the rabbit polyclonal antibodies. Anti-human, anti mouse antibodies to highly immunogenic selected peptide sequences are" monoclonal like" since the epitope to which they are directed is less than 35 amino acids long.
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Latin name
Oryctolagus cuniculus
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Source
Recombinants or rec. proteins
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Group
recombinants
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French translation
anticorps
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Gene target
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Gene symbol
RNU6-9, PIRC45, PIRC47, PIRC38, PIRC43, PIRC37
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Short name
CA19-9/Sialyl Lewisa (GI Tumor ) Recombinant Rabbit Monoclonal Antibody [Clone CA19 9/1390R]
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Technique
Recombinant, Antibody, Rabbit, antibodies against human proteins, antibodies for, Component cell markers and DNA bp. markers are genetic markers er genes or DNA sequences with a known location on a chromosome that can be used to identify individuals or species. Protein markers in kDA. Monoclonals or monoclonal antibodies, E. coli recombinant proteins are genetic recombinations in Escherichia coli, supplied as white sterile powder lyopillized. MyBioSource advises they will be reconstituted in a buffer soluion or culture medium for cell culture.
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Host
Rabbit, Rabbits
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Isotype
IgG, kappa
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Alternative name
CA19-9/Sialyl Lewisa (GI Tumor detection labelled) Rec. production species: rabbit monoclonal (antibody to-) [clonality CA19.9/1390R]
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Alternative technique
rec, antibodies, rabbit-anti
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Clone name
CA19
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Tissue
tumor
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Gene info
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Identity
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Gene
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Long gene name
RNA, U6 small nuclear 9
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Synonyms
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Locus
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Discovery year
2008-06-10
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
Gene info
Gene info
Gene info
Gene info
Gene info
MeSH Data
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Name
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Concept
Scope note:
The initial culturing of cells derived directly from fresh TISSUES.
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Tree numbers
- E01.370.225.500.223.500
- E05.200.500.265.500
- E05.242.223.500
- E05.481.500.249.500
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Qualifiers
ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data
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