BimS, EL, L (BOD, Bcl2l11, BCL2-like 11 Apoptosis Facilitator, Bcl2 Interacting Mediator of Cell Death)

• Catalog number
  MBS603522
• Price
  Please ask
• Size
  0.1 mg

• Products_type
  Antibody
• Products_short_name
  [BimS, EL, L]
• Products_name_syn
  [Anti -BimS, EL, L (BOD, Bcl2l11, BCL2-like 11 Apoptosis Facilitator, Bcl2 Interacting Mediator of Cell Death)]
• Other_names
  [Bcl-2-like protein 11; Bcl-2-like protein 11; bcl-2-like protein 11; bcl-2 interacting protein Bim; bcl-2-related ovarian death agonist; bcl-2 interacting mediator of cell death; BCL2-like 11 (apoptosis facilitator); Bcl2-interacting mediator of cell death]
• Other_gene_names
  [BCL2L11; BCL2L11; BAM; BIM; BOD; BIM; Bcl2-L-11]
• Clonality
  Monoclonal
• Clone
  [6D165]
• Reactivity
  Human, Monkey, Mouse
• Specificity
  Recognizes an epitope within aa 20-40 of human, mouse and monkey BimL, BimEL, and BimS. Also recognizes the six novel isoforms of human Bim, generated by alternative splicing and lacking the C-terminal hydrophobic region recently identified.
• Purity
  Affinity Purified Purified by Protein G affinity chromatography.
• Form
  Liquid. Protein G affinity purified antibody in PBS containing 0.02% sodium azide.
• Storage_stability
  May be stored at 4 degree C for short-term only. For long-term storage and to avoid repeated freezing and thawing, aliquot and store at -20 degree C. Aliquots are stable for at least 12 months at -20 degree C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
• Tested_application
  ELISA (EL/EIA), Western Blot (WB), Immunoprecipitation (IP), Immunohistochemistry (IHC), Immunocytochemistry (ICC), Flow Cytometry (FC/FACS)
• Description
  This 1 is suited for programmed cell-death studies. For cells, cell lines and tissues in culture till half confluency.

• Gene target
  BimS   BOD   Bcl2l11   BCL2-like   Facilitator   Bcl2   Interacting   Mediator   Death  
• Gene symbol
  BCL2, BCL2L11
• Short name
  BimS, EL, L (BOD, Bcl2l11, BCL2-like 11 Apoptosis Facilitator, Bcl2 Interacting Mediator of Death)
• Technique
  apoptosis, apoptosis pathway
• Host
  Rat
• Isotype
  IgG2a
• Alternative name
  BimS, EL, L (BOD, B-cellular CLL/lymphoma 2-like 11 (apoptosis facilitator), B-cellular CLL/lymphoma 2-like 11 programmed cellular destruction Facilitator, B-cellular CLL/lymphoma 2 Interacting Mediator on cellular Death)
• Alternative technique
  celldeath
• Alternative to gene target
  B-cell CLL/lymphoma 2, Bcl-2 and PPP1R50, BCL2 and IDBG-4354 and ENSG00000171791 and 596, protein phosphatase 2A binding, nuclei, Bcl2 and IDBG-185673 and ENSMUSG00000057329 and 12043, BCL2 and IDBG-645006 and ENSBTAG00000019302 and 281020
• Tissue
  cell

Gene info

• Identity
  HGNC:990
• Gene
  BCL2
• Long gene name
  BCL2 apoptosis regulator
• Synonyms gene name
  • B-cell CLL/lymphoma 2
  • BCL2, apoptosis regulator
• Synonyms
  • Bcl-2
  • PPP1R50
• Synonyms name
  • protein phosphatase 1, regulatory subunit 50
• GenBank acession
  • M14745
• Locus
  18q21.33
• Discovery year
  2001-06-22
• Entrez gene record
  596
• RefSeq identity
  • NM_000633
  • NM_000657
• Classification
  • BCL2 family
  • Protein phosphatase 1 regulatory subunits
• VEGA ID
  OTTHUMG00000132791
• Locus Specific Databases
  • LRG_1113

Gene info

• Identity
  HGNC:994
• Gene
  BCL2L11
• Long gene name
  BCL2 like 11
• Synonyms gene name
  • BCL2-like 11 (apoptosis facilitator)
• Synonyms
  • BOD
  • BimL
  • BimEL
  • BimS
  • BIM
• GenBank acession
  • AF032458
• Locus
  2q13
• Discovery year
  1999-12-10
• Entrez gene record
  10018
• Pubmed identfication
  • 9731710
  • 9430630
• Classification
  • BCL2 homology region 3 (BH3) only
• VEGA ID
  OTTHUMG00000131256
• Locus Specific Databases
  • LRG_620

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