APRIL, ED2 (a Proliferation Inducing Ligand, TALL-2, TNF and ApoL-related Leukocyte-expressed Ligand 2, TRDL-1a, TNF-related Death Ligand 1a, TNFSF13)

  • Catalog number
    MBS612868
  • Price
    Please ask
  • Size
    5x0.1 mg
  • Products_type
    Antibody
  • Products_short_name
    [APRIL, ED2]
  • Products_name_syn
    [Anti -APRIL, ED2 (a Proliferation Inducing Ligand, TALL-2, TNF and ApoL-related Leukocyte-expressed Ligand 2, TRDL-1a, TNF-related Death Ligand 1a, TNFSF13)]
  • Clonality
    Polyclonal
  • Reactivity
    Human, Mouse, Rat
  • Specificity
    Recognizes APRIL at ~27kD. Species Crossreactivity: mouse, rat
  • Purity
    Affinity Purified Purified by immunoaffinity chromatography.
  • Form
    Supplied as a liquid in PBS, pH 7.2, 0.02% sodium azide.
  • Storage_stability
    May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
  • Tested_application
    ELISA (EL/EIA), Western Blot (WB), Immunohistochemistry (IHC)
  • Description
    FAS ligand and other ligands are binding to the receptor for signaling pathways for example in apoptosis or JNK signaling. Receptor agonists are often tested for drug development.
  • Gene
    Tumor necrosis factor (TNFa, tumor necrosis factor alpha, TNFα, cachexin, or cachectin) is a cell signaling protein (cytokine) involved in systemic inflammation and is one of the cytokines that make up the acute phase reaction. It is produced chiefly by activated macrophages, although it can be produced by many other cell types such as CD4+ lymphocytes, NK cells, neutrophils, mast cells, eosinophils, and neurons. TNFb or TNF beta also bin on TNF receptors for Th1 activation.
  • Gene target
    APRIL   ED2   Proliferation   Ligand   TALL-2   TNF   ApoL-related   Leukocyte-expressed   Ligand   TRDL-1a   TNF-related   Death   Ligand   TNFSF13  
  • Gene symbol
    TNF, TNFRSF1A, TNFRSF1B, TNFSF13, LTBR, ANP32B, TNFSF12-TNFSF13, GJB6, TNFSF13B, MIR7-2
  • Short name
    APRIL, ED2 (a Proliferation Ligand, TALL-2, TNF ApoL- Leukocyte-expressed Ligand 2, TRDL-1a, TNF- Death Ligand 1a, TNFSF13)
  • Host
    Rabbit
  • Isotype
    IgG
  • Alternative name
    APRIL, ED2 (a expantion Inducing Ligand, TALL-2, tumor necrosis factor and ApoL-related Leukocyte-expressed Ligand 2, TRDL-1a, tumor necrosis factor-related Death Ligand 1a, tumor necrosis factor (ligand) superfamily, member 13)
  • Alternative to gene target
    tumor necrosis factor (ligand) superfamily, member 13, APRIL and CD256 and TALL-2 and TALL2 and TRDL-1 and ZTNF2, TNFSF13 and IDBG-25388 and ENSG00000161955 and 8741, protein binding, nuclei, Tnfsf13 and IDBG-488114 and ENSMUSG00000089669 and 69583, TNFSF13 and IDBG-635008 and ENSBTAG00000000130 and 100551513,538567
Gene info
Gene info
Gene info
Gene info
  • Identity
    HGNC:11928
  • Gene
    TNFSF13
  • Long gene name
    TNF superfamily member 13
  • Synonyms gene name
    • tumor necrosis factor (ligand) superfamily, member 13
  • Synonyms
  • GenBank acession
  • Locus
    17p13.1
  • Discovery year
    1998-12-04
  • Entrez gene record
    8741
  • Pubmed identfication
  • RefSeq identity
  • Classification
    • Tumor necrosis factor superfamily
    • CD molecules
  • VEGA ID
    OTTHUMG00000108145
Gene info
Gene info
Gene info
Gene info
Gene info
Gene info
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APRIL ED2 a Proliferation Ligand TALL 2 TNF ApoL Leukocyte e
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