Anti-TIGIT, Rabbit IgG, kappa Antibody
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Catalog numberMBS847835
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Price:
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Size5x0.2 mg
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Products_typeAntibody
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Products_short_name[TIGIT, IgG, kappa]
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Products_name_syn[T Cell Immunoreceptor With Ig And ITIM Domains; V-Set And Immunoglobulin Domain Containing Protein 9; V-Set And Transmembrane Domain Containing Protein 3; VSIG9; VSTM3; T Cell Immunoreceptor With Ig And ITIM Domains; Washington University Cell Adhesion Molecule; WUCAM]
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Other_names[T-cell immunoreceptor with Ig and ITIM domains; T-cell immunoreceptor with Ig and ITIM domains; T-cell immunoreceptor with Ig and ITIM domains; T cell immunoreceptor with Ig and ITIM domains; V-set and transmembrane domain-containing protein 3]
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Products_gene_name[TIGIT]
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Other_gene_names[Tigit; Tigit; Vstm3]
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ClonalityMonoclonal
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Clone[4D4]
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ReactivityMouse
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SpecificityRecombinant monoclonal antibody manufactured using Recombinant Platform with variable regions from the hybridoma 4D4 to detect TIGIT expression in mouse. 4D4 is an agonistic anti-TIGIT antibody, and addition of anti-CD3/anti-CD28 stimulated T cells to plate bound 4D4 is known to inhibit their proliferation. Further, 4D4 has been used in order to identify genes that are downstream of TIGIT signaling in Tregs, as TIGIT engagement might modulate the Treg phenotype in tumor tissue.
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PurityProtein A purification
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FormColorless liquid. In PBS with 0.02% Proclin 300
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Concentration1mg/ml
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Storage_stabilityStore at -20 degree C The antibody solution should be gently mixed before use. Shelf life: ~12 months
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Tested_applicationAgonist, Flow Cytometry (FC/FACS)
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DescriptionThis antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Antibody for research use.
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PropertiesIf you buy Antibodies supplied by MyBioSource they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
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AboutImmunoglobulin gamma, IgG, mouse monoclonal H&L chain clones or rabbit, goat polyclonal antibodies have 4 parts. There are 2 heavy chains, 2 light chains. The IgG antibody has 2 antigen binding sites. They represent 70% or more of serum antibodies. This antibody can be antigen purified or protein A or G purified. For storage sodium azide is added or you can call us to request azide free antibody preparations. These will need colder storage temperatures. Rabbits are used for polyclonal antibody production by MyBioSource. Rabbit antibodies are very stable and can be stored for several days at room temperature. MyBioSource adds sodium azide and glycerol to enhance the stability of the rabbit polyclonal antibodies. Anti-human, anti mouse antibodies to highly immunogenic selected peptide sequences are" monoclonal like" since the epitope to which they are directed is less than 35 amino acids long.
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Latin nameOryctolagus cuniculus
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French translationanticorps
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Gene target
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Gene symbolTIGIT
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Short nameAnti-TIGIT, Rabbit IgG, kappa Antibody
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TechniqueAntibody, Rabbit, anti-, anti, IgG, antibody to, antibodies, antibodies against human proteins, antibodies for, IgGs
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HostRabbit, Rabbits
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IsotypeRabbit IgG, kappa, IgG
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Alternative nameAntibody toTIGIT, production species: rabbit Immunoglobulin G, kappa (antibody to-)
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Alternative techniqueantibodies, rabbit-anti, immunoglobulins
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Alternative to gene targetT cell immunoreceptor with Ig and ITIM domains, TIGIT and IDBG-50851 and ENSG00000181847 and 201633, protein binding, Cell surfaces, Tigit and IDBG-161101 and ENSMUSG00000071552 and 100043314, TIGIT and IDBG-632631 and ENSBTAG00000011921 and 100140801
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Gene info
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Identity
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Gene
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Long gene nameT cell immunoreceptor with Ig and ITIM domains
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Synonyms gene
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Synonyms gene name
- VSIG9, VSTM3
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Synonyms
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GenBank acession
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Locus
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Discovery year2006-02-07
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- V-set domain containing
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VEGA ID
MeSH Data
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Name
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ConceptScope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
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Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
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Qualifiersethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data