Anti-TIGIT, Rabbit IgG, kappa Antibody

#

• Catalog number
  MBS847835
• Price:

  2944.14 USD

  Ask for price
• Size
  5x0.2 mg

# #

• Products_type
  Antibody
• Products_short_name
  [TIGIT, IgG, kappa]
• Products_name_syn
  [T Cell Immunoreceptor With Ig And ITIM Domains; V-Set And Immunoglobulin Domain Containing Protein 9; V-Set And Transmembrane Domain Containing Protein 3; VSIG9; VSTM3; T Cell Immunoreceptor With Ig And ITIM Domains; Washington University Cell Adhesion Molecule; WUCAM]
• Other_names
  [T-cell immunoreceptor with Ig and ITIM domains; T-cell immunoreceptor with Ig and ITIM domains; T-cell immunoreceptor with Ig and ITIM domains; T cell immunoreceptor with Ig and ITIM domains; V-set and transmembrane domain-containing protein 3]
• Products_gene_name
  [TIGIT]
• Other_gene_names
  [Tigit; Tigit; Vstm3]
• Clonality
  Monoclonal
• Clone
  [4D4]
• Reactivity
  Mouse
• Specificity
  Recombinant monoclonal antibody manufactured using Recombinant Platform with variable regions from the hybridoma 4D4 to detect TIGIT expression in mouse. 4D4 is an agonistic anti-TIGIT antibody, and addition of anti-CD3/anti-CD28 stimulated T cells to plate bound 4D4 is known to inhibit their proliferation. Further, 4D4 has been used in order to identify genes that are downstream of TIGIT signaling in Tregs, as TIGIT engagement might modulate the Treg phenotype in tumor tissue.
• Purity
  Protein A purification
• Form
  Colorless liquid. In PBS with 0.02% Proclin 300
• Concentration
  1mg/ml
• Storage_stability
  Store at -20 degree C The antibody solution should be gently mixed before use. Shelf life: ~12 months
• Tested_application
  Agonist, Flow Cytometry (FC/FACS)
• Description
  This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Antibody for research use.
• Properties
  If you buy Antibodies supplied by MyBioSource they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• About
  Immunoglobulin gamma, IgG, mouse monoclonal H&L chain clones or rabbit, goat polyclonal antibodies have 4 parts. There are 2 heavy chains, 2 light chains. The IgG antibody has 2 antigen binding sites. They represent 70% or more of serum antibodies. This antibody can be antigen purified or protein A or G purified. For storage sodium azide is added or you can call us to request azide free antibody preparations. These will need colder storage temperatures. Rabbits are used for polyclonal antibody production by MyBioSource. Rabbit antibodies are very stable and can be stored for several days at room temperature. MyBioSource adds sodium azide and glycerol to enhance the stability of the rabbit polyclonal antibodies. Anti-human, anti mouse antibodies to highly immunogenic selected peptide sequences are" monoclonal like" since the epitope to which they are directed is less than 35 amino acids long.
• Latin name
  Oryctolagus cuniculus
• French translation
  anticorps

#

• Gene target
  TIGIT   kappa  
• Gene symbol
  TIGIT
• Short name
  Anti-TIGIT, Rabbit IgG, kappa Antibody
• Technique
  Antibody, Rabbit, anti-, anti, IgG, antibody to, antibodies, antibodies against human proteins, antibodies for, IgGs
• Host
  Rabbit, Rabbits
• Isotype
  Rabbit IgG, kappa, IgG
• Alternative name
  Antibody toTIGIT, production species: rabbit Immunoglobulin G, kappa (antibody to-)
• Alternative technique
  antibodies, rabbit-anti, immunoglobulins
• Alternative to gene target
  T cell immunoreceptor with Ig and ITIM domains, TIGIT and IDBG-50851 and ENSG00000181847 and 201633, protein binding, Cell surfaces, Tigit and IDBG-161101 and ENSMUSG00000071552 and 100043314, TIGIT and IDBG-632631 and ENSBTAG00000011921 and 100140801

Gene info

• Identity
  HGNC:26838
• Gene
  TIGIT
• Long gene name
  T cell immunoreceptor with Ig and ITIM domains
• Synonyms gene
  • VSIG9
  • VSTM3
• Synonyms gene name
  • VSIG9, VSTM3
• Synonyms
  • FLJ39873
  • DKFZp667A205
• GenBank acession
  • AK097192
• Locus
  3q13.31
• Discovery year
  2006-02-07
• Entrez gene record
  201633
• Pubmed identfication
  • 19011627
• RefSeq identity
  • NM_173799
• Classification
  • V-set domain containing
• VEGA ID
  OTTHUMG00000159331

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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