Anti-Phospho-Tyr1252 NMDA Receptor NR2B Subunit

• Catalog number
  MBS502089
• Price
  Please ask
• Size
  5x0.1 mL

• Products_type
  Antibody
• Products_short_name
  [NMDA NR2B Subunit (Tyr1252)]
• Other_names
  [glutamate receptor ionotropic, NMDA 2B; Glutamate receptor ionotropic, NMDA 2B; glutamate receptor ionotropic, NMDA 2B; NR2B; NMDAR2B; glutamate receptor, ionotropic, NMDA2B; N-methyl D-aspartate receptor subtype 2B; glutamate [NMDA] receptor subunit epsilon-2; glutamate receptor, ionotropic, N-methyl D-aspartate 2B; Glutamate [NMDA] receptor subunit epsilon-2; N-methyl D-aspartate receptor subtype 2B]
• Products_gene_name
  [GRIN2B]
• Other_gene_names
  [Grin2b; Grin2b; GluN2B; GluN2B; NMDAR2B; NR2B]
• Clonality
  Polyclonal
• Reactivity
  Rat
• Specificity
  Specific for ~180k NMDAR NR2B subunit protein phosphorylated at Tyr1252. Immunolabeling of the NMDA NR2B subunit band is blocked by the phosphopeptide used as the antigen but not by the corresponding dephosphopeptide. Immunolabeling is also blocked by lambda-phosphatase treatment. The antibody may also show some slight reactivity with Tyr1246 of NR2A.
• Purity
  Affinity Purified (Prepared from rabbit serum by affinity purification via sequential chromatography on phospho- and dephosphopeptide affinity columns.)
• Form
  100 ul in 10 mM HEPES (pH 7.5), 150 mM NaCl, 100 ug per ml BSA and 50% glycerol. Adequate amount of material to conduct 10-mini Western Blots.
• Storage_stability
  Store at -20 degree C; stable for at least one year
• Tested_application
  Western Blot (WB), Immunohistochemistry (IHC)
• Description
  This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Antibody for research use. The receptors are ligand binding factors of type 1, 2 or 3 and protein-molecules that receive chemical-signals from outside a cell. When such chemical-signals couple or bind to a receptor, they cause some form of cellular/tissue-response, e.g. a change in the electrical-activity of a cell. In this sense, am olfactory receptor is a protein-molecule that recognizes and responds to endogenous-chemical signals, chemokinesor cytokines e.g. an acetylcholine-receptor recognizes and responds to its endogenous-ligand, acetylcholine. However, sometimes in pharmacology, the term is also used to include other proteins that are drug-targets, such as enzymes, transporters and ion-channels.

• Gene target
  Phospho-Tyr1252   NMDA   Receptor   NR2B   Subunit  
• Short name
  Anti-Phospho-Tyr1252 NMDA Receptor NR2B Subunit
• Technique
  anti-, anti, antibody to, antibodies
• Host
  Rabbit
• Alternative name
  Antibody tophosphorilated-Tyr1252 NMDA Receptor NR2B functionnal sequence
• Alternative technique
  antibodies

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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