Anti-Phospho-Thr52 Activating Transcription Factor 2 (ATF2)
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Catalog number
MBS502185
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Price
Please ask
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Size
0.1 mL
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Products_type
Antibody
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Products_short_name
[ATF2 (Thr52)]
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Other_names
[cyclic AMP-dependent transcription factor ATF-2 isoform 1; Cyclic AMP-dependent transcription factor ATF-2; cyclic AMP-dependent transcription factor ATF-2; histone acetyltransferase ATF2; cAMP-dependent transcription factor ATF-2; cAMP-responsive element-binding protein 2; cAMP response element-binding protein CRE-BP1; cyclic AMP-responsive element-binding protein 2; cAMP responsive element binding protein 2, formerly; activating transcription factor 2 splice variant ATF2-var2; activating transcription factor 2; Activating transcription factor 2; Cyclic AMP-responsive element-binding protein 2; CREB-2; cAMP-responsive element-binding protein 2; HB16; Histone acetyltransferase ATF2; cAMP response element-binding protein CRE-BP1]
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Products_gene_name
[ATF2]
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Other_gene_names
[ATF2; ATF2; HB16; CREB2; TREB7; CREB-2; CRE-BP1; CREB2; CREBP1; cAMP-dependent transcription factor ATF-2; CREB-2]
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Clonality
Polyclonal
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Reactivity
Human
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Specificity
Specific for the ~72k ATF2 protein phosphorylated at Thr52. Immunolabeling of the ATF2 band is reduced by treatment of the cells with the PKC catalytic inhibitor Gö6850.
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Purity
Affinity Purified (Prepared from rabbit serum by affinity purification via sequential chromatography on phospho and dephosphopeptide affinity columns.)
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Form
100 ul in 10 mM HEPES (pH 7.5), 150 mM NaCl, 100 ug per ml BSA and 50% glycerol.
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Storage_stability
Store at -20 degree C; stable for at least one year.
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Tested_application
Western Blot (WB)
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Description
This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Antibody for research use. Aplha, transcription related growth factors and stimulating factors or repressing nuclear factors are complex subunits of proteins involved in cell differentiation. Complex subunit associated factors are involved in hybridoma growth, Eosinohils, eritroid proliferation and derived from promotor binding stimulating subunits on the DNA binding complex. NFKB 105 subunit for example is a polypetide gene enhancer of genes in B cells. The activation of transcription factor subunits is the first step of gene expression, in which a particular segment of DNA is copied into RNA (mRNA) by the enzyme RNA polymerases. Transcription factors, unites and elongations can be RNA and DNA nucleic acids, base pairs of nucleotides . Converting from DNA to RNA is made by enzymatic reactions. During transcription, a DNA sequence is read by an RNA polymerase, which produces a complementary, anti-parallel RNA strand called a primary transcript. Transcriptions are key functions in signal transduction pathways. Signaling ligand binding transcription factors play an important role in transduction cascades.
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Gene target
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Gene symbol
GDNF, ATF2
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Short name
Anti-Phospho-Thr52 Activating Transcription Factor 2 (ATF2)
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Technique
anti-, anti, antibody to, antibodies
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Host
Rabbit
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Alternative name
Antibody tophosphorilated-Thr52 Activating Transcription Factor 2 (ATF2)
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Alternative technique
antibodies
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Gene info
Gene info
MeSH Data
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Name
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Concept
Scope note:
Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
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Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
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Qualifiers
ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data
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